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Auteur Mohamed Bougrida |
Documents disponibles écrits par cet auteur (3)
Affiner la recherche Interroger des sources externesEffet du poids et de la distribution de la masse grasse sur la fertilité masculine / Mohamed Lahmadi
Titre : Effet du poids et de la distribution de la masse grasse sur la fertilité masculine Type de document : texte imprimé Auteurs : Mohamed Lahmadi, Auteur ; Univ. de Constantine, Éditeur scientifique ; Mohamed Bougrida, Directeur de thèse Année de publication : 2009 Importance : 88 p. Note générale : Magister
01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CDLangues : Français (fre) Catégories : Français - Anglais
BiologieTags : IMC Tour de taille Obésité Hypofertilité Qualité du sperme Index. décimale : 570 Sciences de la vie. Biologie En ligne : ../theses/biologie/LAH5503.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=1788 Effet du poids et de la distribution de la masse grasse sur la fertilité masculine [texte imprimé] / Mohamed Lahmadi, Auteur ; Univ. de Constantine, Éditeur scientifique ; Mohamed Bougrida, Directeur de thèse . - 2009 . - 88 p.
Magister
01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : IMC Tour de taille Obésité Hypofertilité Qualité du sperme Index. décimale : 570 Sciences de la vie. Biologie En ligne : ../theses/biologie/LAH5503.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=1788 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité LAH/5503 LAH/5503 Thèse Bibliothèque principale Thèses Disponible
Titre : Le profil génétique de l’asthme atopique Type de document : texte imprimé Auteurs : Dahbia ines Dahmani, Auteur ; Mohamed Bougrida, Directeur de thèse ; Karima Sifi, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 250 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Asthme Atopie polymorphisme FcεRIβ RsaI-in2 C-590 T IL-4 IgE Asthma Atopy polymorphism تأتب الربو تعدد الأشكالT الجلوبيولين Index. décimale : 570 Sciences de la vie. Biologie Résumé : Atopy is a common familial syndrome that is due to interacting genetic and environmental factors.
The atopic diseases include asthma, atopic dermatitis and allergic rhinitis. The aim of this study was to investigate the potential link between -590C/T and RsaI-in2 and, the levels of IgE and IL-4, atopic asthma in a young adult population. A total of 80 patients with atopic asthma and 80 non-atopic, nonallergic and non-asthmatic controls and 12 families in which at least one of their children was asthmatic were include. Atopic asthma status was confirmed by means of the skin prick test, The IgE levels were measured by Quantia IgE immunoturbidimetric assay, while, Interleukin (IL)-4 concentrations were determined by immunosorbent assay. IL-4 C-590T and RsaI-in2 polymorphisms were determined by the polymerase chain reaction-restriction fragment length polymorphism method
(RFLP-PCR) using the BsmF1 and RsaI enzymes. Our findings revealed that women are much more likely to develop asthma than men. Gene analyses reviled that, the IL-4 C-590T SNP shows a significant difference between asthmatic and controls when comparing the TT vs. CC (OR, 3.63; OR 95% CI, 1.16-11.63; p-value =0.01) and TT vs. CT (OR, 2.48; OR 95% CI, 0.91 -6.95; p-value =0.05) genotypes. We also demonstrated that patients with heterozygous CT (55%) and homozygous TT (23.75%) genotypes of the IL-4 C-590T polymorphism showed significantly higher of IgE levels (pvalue =0.0000) and serum levels of IL-4 (p-value =0.0000). Whereas, for the second polymorphism no statistically significant difference between the asthma and the expression of RsaI-in2 polymorphism it was found that AA vs. BB (OR, 0.89; IC à 95% de 0.31 à 2.49; p-value = 0.82), BB vs. AB (OR, 1.21; IC à 95% de 0.48 à 3.04; p-value =0.67), AA vs. AB+BB (OR, 0.76; IC à 95% de 0.37 à 1.57; p-value =0.46), and AA+AB vs. BB (OR, 1.10; IC à 95% de 0.45 à 2.68; p-value = 0.82).
By against, a highly significant association was observed between the IgE, IL-4 serum levels and AA, AB, BB genotypes when comparing the asthmatiques group and controls the results were as follows (p-value =0.0000) for IgE and (p-value =0.0000) for IL-4. While for the family study our data found that, the T allele is associated with atopic diseases and herited from the mothers. Whereas for the RsaI-in2 polymorphism our results show that, this polymorphism is associated with atopy and that the mutated allele B is not only maternally inherited, but rather inherited from both parents.
Diplôme : Doctorat En ligne : ../theses/biologie/BAH6974.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10372 Le profil génétique de l’asthme atopique [texte imprimé] / Dahbia ines Dahmani, Auteur ; Mohamed Bougrida, Directeur de thèse ; Karima Sifi, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 250 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Asthme Atopie polymorphisme FcεRIβ RsaI-in2 C-590 T IL-4 IgE Asthma Atopy polymorphism تأتب الربو تعدد الأشكالT الجلوبيولين Index. décimale : 570 Sciences de la vie. Biologie Résumé : Atopy is a common familial syndrome that is due to interacting genetic and environmental factors.
The atopic diseases include asthma, atopic dermatitis and allergic rhinitis. The aim of this study was to investigate the potential link between -590C/T and RsaI-in2 and, the levels of IgE and IL-4, atopic asthma in a young adult population. A total of 80 patients with atopic asthma and 80 non-atopic, nonallergic and non-asthmatic controls and 12 families in which at least one of their children was asthmatic were include. Atopic asthma status was confirmed by means of the skin prick test, The IgE levels were measured by Quantia IgE immunoturbidimetric assay, while, Interleukin (IL)-4 concentrations were determined by immunosorbent assay. IL-4 C-590T and RsaI-in2 polymorphisms were determined by the polymerase chain reaction-restriction fragment length polymorphism method
(RFLP-PCR) using the BsmF1 and RsaI enzymes. Our findings revealed that women are much more likely to develop asthma than men. Gene analyses reviled that, the IL-4 C-590T SNP shows a significant difference between asthmatic and controls when comparing the TT vs. CC (OR, 3.63; OR 95% CI, 1.16-11.63; p-value =0.01) and TT vs. CT (OR, 2.48; OR 95% CI, 0.91 -6.95; p-value =0.05) genotypes. We also demonstrated that patients with heterozygous CT (55%) and homozygous TT (23.75%) genotypes of the IL-4 C-590T polymorphism showed significantly higher of IgE levels (pvalue =0.0000) and serum levels of IL-4 (p-value =0.0000). Whereas, for the second polymorphism no statistically significant difference between the asthma and the expression of RsaI-in2 polymorphism it was found that AA vs. BB (OR, 0.89; IC à 95% de 0.31 à 2.49; p-value = 0.82), BB vs. AB (OR, 1.21; IC à 95% de 0.48 à 3.04; p-value =0.67), AA vs. AB+BB (OR, 0.76; IC à 95% de 0.37 à 1.57; p-value =0.46), and AA+AB vs. BB (OR, 1.10; IC à 95% de 0.45 à 2.68; p-value = 0.82).
By against, a highly significant association was observed between the IgE, IL-4 serum levels and AA, AB, BB genotypes when comparing the asthmatiques group and controls the results were as follows (p-value =0.0000) for IgE and (p-value =0.0000) for IL-4. While for the family study our data found that, the T allele is associated with atopic diseases and herited from the mothers. Whereas for the RsaI-in2 polymorphism our results show that, this polymorphism is associated with atopy and that the mutated allele B is not only maternally inherited, but rather inherited from both parents.
Diplôme : Doctorat En ligne : ../theses/biologie/BAH6974.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10372 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité DAH/6974 DAH/6974 Thèse Bibliothèque principale Thèses Disponible
Titre : Profil inflammatoire systémique des fumeurs atteints de bronchopneumopathie chronique obstructive comparés aux fumeurs indemnes de bronchopneumopathie chronique obstructive. Type de document : texte imprimé Auteurs : Yousra Mosrane, Auteur ; Mohamed Bougrida, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 130 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Biochimie et Biologie Cellulaire et Moléculaire:Biologie et Santé Tabac spirométrie BPCO inflammation systémique, VEMS, VEMS/CVF. Tobacco spirometry COPD systemic inflammation, FEV1, FEV1/FVC. تبغ قياس التنفس Index. décimale : 570 Sciences de la vie. Biologie Résumé : Studies comparing the systemic inflammatory profiles of smokers with and without COPD present discordant findings. The aim of our study is to compare the systemic inflammatory profile of smokers with and without COPD. This is a cross-sectional comparative study. Two groups of active smokers of more than 10 pack-years were included: 56 consecutives stable COPD (postbronchodilator FEV1/FVC < 0.70) and 32 consecutives non-COPD (postbronchodilator FEV1/FVC ≥ 0.70). Smoking and clinical, anthropometric and spirometric data were noted. The following blood biomarkers were identified: leukocytes, hemoglobin, tumor necrosis factor- (TNF-), nterleukin-6 (IL- 6), C reactive protein (CRP), erythrocyte sedimentation rate (ESR). According to the levels (normal/abnormal) of these markers, two groups of smokers were formed. Quantitative and qualitative data were expressed, respectively, as means±SD and percentages. Compared to the non-COPD group, the COPD group was older (56±12 vs. 65±8 years) and had a higher smoking consumption (30±18 vs. 52±31 pack-years). Compared to the nonCOPD group, the COPD group had higher values of CRP (2.06±1.24 vs. 11.32±11.03 mg/L), of ESR (9.59±8.29 vs. 15.96±11.56), of IL-6 (9.28±4.69 vs. 20.27±5.31 ng/L) and of TNF- (18.38±7.98 vs. 8.62±3.72 ng/L). Compared to the non-COPD group, the COPD group included higher percentages of smokers with elevated CRP (0 vs. 32%), with leukocytosis (6 vs. 16%), with higher levels of IL-6 (81 vs. 98%) or TNF-α (91 vs. 100%). Smokers with COPD, compared to smokers free from COPD, have a marked systemic inflammation. Note de contenu : Annexes. Diplôme : Doctorat En ligne : ../theses/biologie/MOS7483.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11315 Profil inflammatoire systémique des fumeurs atteints de bronchopneumopathie chronique obstructive comparés aux fumeurs indemnes de bronchopneumopathie chronique obstructive. [texte imprimé] / Yousra Mosrane, Auteur ; Mohamed Bougrida, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 130 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Biochimie et Biologie Cellulaire et Moléculaire:Biologie et Santé Tabac spirométrie BPCO inflammation systémique, VEMS, VEMS/CVF. Tobacco spirometry COPD systemic inflammation, FEV1, FEV1/FVC. تبغ قياس التنفس Index. décimale : 570 Sciences de la vie. Biologie Résumé : Studies comparing the systemic inflammatory profiles of smokers with and without COPD present discordant findings. The aim of our study is to compare the systemic inflammatory profile of smokers with and without COPD. This is a cross-sectional comparative study. Two groups of active smokers of more than 10 pack-years were included: 56 consecutives stable COPD (postbronchodilator FEV1/FVC < 0.70) and 32 consecutives non-COPD (postbronchodilator FEV1/FVC ≥ 0.70). Smoking and clinical, anthropometric and spirometric data were noted. The following blood biomarkers were identified: leukocytes, hemoglobin, tumor necrosis factor- (TNF-), nterleukin-6 (IL- 6), C reactive protein (CRP), erythrocyte sedimentation rate (ESR). According to the levels (normal/abnormal) of these markers, two groups of smokers were formed. Quantitative and qualitative data were expressed, respectively, as means±SD and percentages. Compared to the non-COPD group, the COPD group was older (56±12 vs. 65±8 years) and had a higher smoking consumption (30±18 vs. 52±31 pack-years). Compared to the nonCOPD group, the COPD group had higher values of CRP (2.06±1.24 vs. 11.32±11.03 mg/L), of ESR (9.59±8.29 vs. 15.96±11.56), of IL-6 (9.28±4.69 vs. 20.27±5.31 ng/L) and of TNF- (18.38±7.98 vs. 8.62±3.72 ng/L). Compared to the non-COPD group, the COPD group included higher percentages of smokers with elevated CRP (0 vs. 32%), with leukocytosis (6 vs. 16%), with higher levels of IL-6 (81 vs. 98%) or TNF-α (91 vs. 100%). Smokers with COPD, compared to smokers free from COPD, have a marked systemic inflammation. Note de contenu : Annexes. Diplôme : Doctorat En ligne : ../theses/biologie/MOS7483.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11315 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité MOS/7483 MOS/7483 Thèse Bibliothèque principale Thèses Disponible
