Removal of Pivaloyl and trityl groups from Tetrazoles and alcohols via Indium, lithium chloride and arene catalyzed lithiation / Aicha Chouti  

Public ISBD Titre : Removal of Pivaloyl and trityl groups from Tetrazoles and alcohols via Indium, lithium chloride and arene catalyzed lithiation Type de document : texte imprimé Auteurs : Aicha Chouti, Auteur ; Cherif Behloul, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 201 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Catégories : Français - Anglais Chimie Tags : Arganic synthesis  tetrazoles  alcohols  lithium  indium  lithium chloride  pivaloyl chloride  trityl ether  tétrazoles  alcools  chlorure de lithium  chlorure de pivaloyle  éther tritylé  لتیترزول  الكحولات  اللیثیوم  الإندیوم  كلورید اللیثیوم  كلورید البیفالویل  تریتیل الاثیر Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript encloses three principal parts: the first part, we have described the synthesis of tetrazoles which are a class of heterocycles with a wide range of applications in medicinal chemistry and in material sciences. We report herein a novel efficient process for transforming a wide variety of nitriles into the corresponding tetrazoles in high yield, using a simple and safe protocol. We have reported in the second part, the protection of tetrazoles using pivaloyl chloride, the same reaction is made to protect a wide range of alcohols with trityl chloride giving trityl ethers and pivaloyl tetrazoles in good yields. Finally, we have reported the use of lithium and a catalytic amount of naphthalene to remove the pivaloyl protecting group from tetrazoles under very mild condition we have reported successfully the use of a new catalyst for the detritylation of trityl ethers using indium and lithium chloride generally with very good yields. Diplôme : Doctorat En ligne : ../theses/chimie/CHO6838.pdf Format de la ressource électronique : pdf Permalink : index.php?lvl=notice_display&id=10113 Removal of Pivaloyl and trityl groups from Tetrazoles and alcohols via Indium, lithium chloride and arene catalyzed lithiation [texte imprimé] / Aicha Chouti, Auteur ; Cherif Behloul, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 201 f. ; 30 cm. 2 copies imprimées disponibles Langues : Français (fre) Catégories : Français - Anglais Chimie Tags : Arganic synthesis  tetrazoles  alcohols  lithium  indium  lithium chloride  pivaloyl chloride  trityl ether  tétrazoles  alcools  chlorure de lithium  chlorure de pivaloyle  éther tritylé  لتیترزول  الكحولات  اللیثیوم  الإندیوم  كلورید اللیثیوم  كلورید البیفالویل  تریتیل الاثیر Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript encloses three principal parts: the first part, we have described the synthesis of tetrazoles which are a class of heterocycles with a wide range of applications in medicinal chemistry and in material sciences. We report herein a novel efficient process for transforming a wide variety of nitriles into the corresponding tetrazoles in high yield, using a simple and safe protocol. We have reported in the second part, the protection of tetrazoles using pivaloyl chloride, the same reaction is made to protect a wide range of alcohols with trityl chloride giving trityl ethers and pivaloyl tetrazoles in good yields. Finally, we have reported the use of lithium and a catalytic amount of naphthalene to remove the pivaloyl protecting group from tetrazoles under very mild condition we have reported successfully the use of a new catalyst for the detritylation of trityl ethers using indium and lithium chloride generally with very good yields. Diplôme : Doctorat En ligne : ../theses/chimie/CHO6838.pdf Format de la ressource électronique : pdf Permalink : index.php?lvl=notice_display&id=10113

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
CHO/6838	CHO/6838	Thèse	Bibliothèque principale	Thèses	Disponible

---

1 (1 - 1 / 1)