Détail de l'auteur
Auteur Cherif Behloul |
Documents disponibles écrits par cet auteur (4)
Affiner la recherche Interroger des sources externesDébenzylation, détritylation des indoles et nouvelle méthode de synthèse de (Rs) N-Tert-Butanesulfinylimine. / Sofiane Ikhlef
Titre : Débenzylation, détritylation des indoles et nouvelle méthode de synthèse de (Rs) N-Tert-Butanesulfinylimine. Type de document : texte imprimé Auteurs : Sofiane Ikhlef, Auteur ; Cherif Behloul, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 213 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : indoles déprotection N-tert-Butanesulfinylimines deprotection أندول ايمين غير متناظر الحماية Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript describes the reductive removal of trityl and benzyl groups from N-protected indoles, using indium, magnesium, zinc and aluminum processes and new method for synthesis an N-tert-Butanesulfinylimines. In the main part: Chapters 1 and 2 we have reported the development of two efficient processes one for transforming a wide variety of indoles into the corresponding derivatives indoles in high yield, using a simple and soft protocol, and other to protect indoles which is our starting materials. Chapter 3 shows the deprotection of the trityl (triphenylmethyl) and benzyl groups, from tritylated and benzylated indoles using indium, magnesium, zinc and aluminum powder to give the corresponding free indoles. In the second main part: we have described anew method for the synthesis ofN-tertButanesulfinylimines with a moderate yield. Diplôme : Doctorat En ligne : ../theses/chimie/IKH7368.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11017 Débenzylation, détritylation des indoles et nouvelle méthode de synthèse de (Rs) N-Tert-Butanesulfinylimine. [texte imprimé] / Sofiane Ikhlef, Auteur ; Cherif Behloul, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 213 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : indoles déprotection N-tert-Butanesulfinylimines deprotection أندول ايمين غير متناظر الحماية Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript describes the reductive removal of trityl and benzyl groups from N-protected indoles, using indium, magnesium, zinc and aluminum processes and new method for synthesis an N-tert-Butanesulfinylimines. In the main part: Chapters 1 and 2 we have reported the development of two efficient processes one for transforming a wide variety of indoles into the corresponding derivatives indoles in high yield, using a simple and soft protocol, and other to protect indoles which is our starting materials. Chapter 3 shows the deprotection of the trityl (triphenylmethyl) and benzyl groups, from tritylated and benzylated indoles using indium, magnesium, zinc and aluminum powder to give the corresponding free indoles. In the second main part: we have described anew method for the synthesis ofN-tertButanesulfinylimines with a moderate yield. Diplôme : Doctorat En ligne : ../theses/chimie/IKH7368.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11017 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité IKH/7368 IKH/7368 Thèse Bibliothèque principale Thèses Disponible
Titre : Metals debenzylation of tetrazoles, and high convergent straightforward stereoselective synthesis of (+)-C(9a)-Epiepiquinamide. Type de document : texte imprimé Auteurs : Meriem Benlahrech, Auteur ; Cherif Behloul, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 131 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE.
2 copies imprimées disponibles
Langues : Anglais (eng) Catégories : Français - Anglais
ChimieTags : Organic chemistry :Organic synthesis Protégés (+)-C(9a)-epiepiquinamide alcaloide aza-Henry N-tert-butanesulfinyl imine Protected alkaloid N-tertbutanesulfinyl imine تيتراوزول المحمية )+( ايببكناميد ازاءهنري ترسيبوتيل سلفينيل ايمين Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript encloses two principal parts:
In the first part, We report the use of three metals for debenzylation of protected tetrazoles: indium, magnesium and zinc, comparing the process of using metals, and taking into account financial aspects, the use of zinc show to be the most effective for substrates non-sensitive to acidic conditions. For substrates sensitive to acid, magnesium or indium metal can be used, can we say that zinc being preferable considering reaction conditions and metal prices. In the second part, We have synthesis from commercially available compounds, the (+)-C(9a)- epiepiquinamide the reaction was carried out in six synthetic operations starting from a diastereoselective aza-Henry reaction of a chiral N-tert-butanesulfinyl imine and ethyl 4- nitrobutanoate, the configuration of the sulfur atom of the sulfinyl group determining the configuration of C(9a) stereocenter in this transformation.Note de contenu : Annexes. Diplôme : Doctorat En ligne : ../theses/chimie/BEN7441.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11219 Metals debenzylation of tetrazoles, and high convergent straightforward stereoselective synthesis of (+)-C(9a)-Epiepiquinamide. [texte imprimé] / Meriem Benlahrech, Auteur ; Cherif Behloul, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 131 f. ; 30 cm.
Doctorat 3éme CYCLE.
2 copies imprimées disponibles
Langues : Anglais (eng)
Catégories : Français - Anglais
ChimieTags : Organic chemistry :Organic synthesis Protégés (+)-C(9a)-epiepiquinamide alcaloide aza-Henry N-tert-butanesulfinyl imine Protected alkaloid N-tertbutanesulfinyl imine تيتراوزول المحمية )+( ايببكناميد ازاءهنري ترسيبوتيل سلفينيل ايمين Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript encloses two principal parts:
In the first part, We report the use of three metals for debenzylation of protected tetrazoles: indium, magnesium and zinc, comparing the process of using metals, and taking into account financial aspects, the use of zinc show to be the most effective for substrates non-sensitive to acidic conditions. For substrates sensitive to acid, magnesium or indium metal can be used, can we say that zinc being preferable considering reaction conditions and metal prices. In the second part, We have synthesis from commercially available compounds, the (+)-C(9a)- epiepiquinamide the reaction was carried out in six synthetic operations starting from a diastereoselective aza-Henry reaction of a chiral N-tert-butanesulfinyl imine and ethyl 4- nitrobutanoate, the configuration of the sulfur atom of the sulfinyl group determining the configuration of C(9a) stereocenter in this transformation.Note de contenu : Annexes. Diplôme : Doctorat En ligne : ../theses/chimie/BEN7441.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11219 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEN/7441 BEN/7441 Thèse Bibliothèque principale Thèses Disponible
Titre : Reductive removal of trityl group from tetrazoles via indium : Zinc and Arene catalyzed lithiation Type de document : texte imprimé Auteurs : Kenza Bouchelouche, Auteur ; Cherif Behloul, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 202 f. Format : 30 cm. Note générale : 2 copies imprimes disponibles Langues : Anglais (eng) Catégories : Français - Anglais
ChimieTags : chimie organique Tétrazoles protéction aréne lithiation cleavage zinc indium trityl Tetrazoles protection arene تيترازول ليثيوم حلقة ارينية حماية ازاحة زنك انديوم تريتيل Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript describes the reductive removal of trityl groups from N-protected
tetrazoles, using indium, zinc and arene-catalysed lithiation processes.
Chapters 1 and 2 report the development of two efficient processes one for transforming a
wide variety of nitriles into the corresponding tetrazoles in high yield, using a simple and sofe
protocole, and other to protect tetrazoles wich is our starting materials.
Chapter 3 shows the deprotection of the trityl (triphenylmethyl) group, from tritylated
tetrazoles using lithium powder and a catalytic amount of naphtalene to give corresponding free
tetrazoles without decomposition of the tetrazole ring.
Chapter 4 describes the reductive cleavage of the same group from the same protected Ntetrazoles using indium as a source of free electron transfer which can show you a good method
even in the presence of the air moister.
Chapter 5 In the latter case, deals with the deblocking of tetrazoles, protected with trityl
group, respectively. Using in this case zinc as a dissolving metal in Methanol/THF, in the
opposite of lithium; this methodology led to the removal of this group from different tetrazoles
even in the presence of the proton source.
Diplôme : Doctorat En ligne : ../theses/chimie/BOU6831.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10123 Reductive removal of trityl group from tetrazoles via indium : Zinc and Arene catalyzed lithiation [texte imprimé] / Kenza Bouchelouche, Auteur ; Cherif Behloul, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 202 f. ; 30 cm.
2 copies imprimes disponibles
Langues : Anglais (eng)
Catégories : Français - Anglais
ChimieTags : chimie organique Tétrazoles protéction aréne lithiation cleavage zinc indium trityl Tetrazoles protection arene تيترازول ليثيوم حلقة ارينية حماية ازاحة زنك انديوم تريتيل Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript describes the reductive removal of trityl groups from N-protected
tetrazoles, using indium, zinc and arene-catalysed lithiation processes.
Chapters 1 and 2 report the development of two efficient processes one for transforming a
wide variety of nitriles into the corresponding tetrazoles in high yield, using a simple and sofe
protocole, and other to protect tetrazoles wich is our starting materials.
Chapter 3 shows the deprotection of the trityl (triphenylmethyl) group, from tritylated
tetrazoles using lithium powder and a catalytic amount of naphtalene to give corresponding free
tetrazoles without decomposition of the tetrazole ring.
Chapter 4 describes the reductive cleavage of the same group from the same protected Ntetrazoles using indium as a source of free electron transfer which can show you a good method
even in the presence of the air moister.
Chapter 5 In the latter case, deals with the deblocking of tetrazoles, protected with trityl
group, respectively. Using in this case zinc as a dissolving metal in Methanol/THF, in the
opposite of lithium; this methodology led to the removal of this group from different tetrazoles
even in the presence of the proton source.
Diplôme : Doctorat En ligne : ../theses/chimie/BOU6831.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10123 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BOU/6831 BOU/6831 Thèse Bibliothèque principale Thèses Disponible
Titre : Removal of Pivaloyl and trityl groups from Tetrazoles and alcohols via Indium, lithium chloride and arene catalyzed lithiation Type de document : texte imprimé Auteurs : Aicha Chouti, Auteur ; Cherif Behloul, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 201 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Arganic synthesis tetrazoles alcohols lithium indium lithium chloride pivaloyl chloride trityl
ether tétrazoles alcools chlorure de lithium chlorure de pivaloyle éther tritylé لتیترزول الكحولات اللیثیوم الإندیوم كلورید اللیثیوم كلورید البیفالویل تریتیل
الاثیرIndex. décimale : 540 Chimie et sciences connexes Résumé : This manuscript encloses three principal parts: the first part, we have described the
synthesis of tetrazoles which are a class of heterocycles with a wide range of applications in
medicinal chemistry and in material sciences. We report herein a novel efficient process for
transforming a wide variety of nitriles into the corresponding tetrazoles in high yield, using a
simple and safe protocol.
We have reported in the second part, the protection of tetrazoles using pivaloyl chloride, the
same reaction is made to protect a wide range of alcohols with trityl chloride giving trityl
ethers and pivaloyl tetrazoles in good yields.
Finally, we have reported the use of lithium and a catalytic amount of naphthalene to remove
the pivaloyl protecting group from tetrazoles under very mild condition we have reported
successfully the use of a new catalyst for the detritylation of trityl ethers using indium and
lithium chloride generally with very good yields.Diplôme : Doctorat En ligne : ../theses/chimie/CHO6838.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10113 Removal of Pivaloyl and trityl groups from Tetrazoles and alcohols via Indium, lithium chloride and arene catalyzed lithiation [texte imprimé] / Aicha Chouti, Auteur ; Cherif Behloul, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 201 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Arganic synthesis tetrazoles alcohols lithium indium lithium chloride pivaloyl chloride trityl
ether tétrazoles alcools chlorure de lithium chlorure de pivaloyle éther tritylé لتیترزول الكحولات اللیثیوم الإندیوم كلورید اللیثیوم كلورید البیفالویل تریتیل
الاثیرIndex. décimale : 540 Chimie et sciences connexes Résumé : This manuscript encloses three principal parts: the first part, we have described the
synthesis of tetrazoles which are a class of heterocycles with a wide range of applications in
medicinal chemistry and in material sciences. We report herein a novel efficient process for
transforming a wide variety of nitriles into the corresponding tetrazoles in high yield, using a
simple and safe protocol.
We have reported in the second part, the protection of tetrazoles using pivaloyl chloride, the
same reaction is made to protect a wide range of alcohols with trityl chloride giving trityl
ethers and pivaloyl tetrazoles in good yields.
Finally, we have reported the use of lithium and a catalytic amount of naphthalene to remove
the pivaloyl protecting group from tetrazoles under very mild condition we have reported
successfully the use of a new catalyst for the detritylation of trityl ethers using indium and
lithium chloride generally with very good yields.Diplôme : Doctorat En ligne : ../theses/chimie/CHO6838.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10113 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité CHO/6838 CHO/6838 Thèse Bibliothèque principale Thèses Disponible
