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Effets de différentes doses de Dexaméthasone sur la fonction thyroïdienne chez le mouton Ouled Djellal / Narimane Kellali
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Titre : Effets de différentes doses de Dexaméthasone sur la fonction thyroïdienne chez le mouton Ouled Djellal Type de document : texte imprimé Auteurs : Narimane Kellali, Auteur ; Mustapha Kerrour, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 92 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
Sciences VétérinairesTags : Thyroïdienne Dexaméthasone Ovin fT4 fT3 Thyroid Dexamethasone Sheep Index. décimale : 636 Sciences Vétérinaires Résumé : Synthetic glucocorticosteroids are widely used in veterinary medicine for their antiinflammatory and immunosuppressive actions. However they are deemed to have
multiple side effects such as hypothyroidism.
The aim of this study was to define the effects of Dexamethasone (DEX) administered
parenterally (IM) at therapeutic doses conventionally used in the anti-inflammatory
and immunosuppressive treatments on the thyroid function in sheep.
Fifteen sheep of Ouled Djellal breeds were randomly divided into three groups of five
sheep each. The animals received an injection of Dexamethasone (DEXALONEND
solution) at a rate of 1.52 mg DEX / J for 6 days for group1 and 3.4 mg DEX / J for 6
days for group 2, the third group has served as control group and did not receive any
treatment. Blood samples taken over a period of 3 weeks were analyzed to define the
plasma levels of free thyroid hormones fT4 fT3.
It has been shown that Dexamethasone induced a significant decrease (P <0.05) of
serum fT4 and fT3 24 hours following the start of treatment. Hormone levels have
returned to their baseline values 24 hours after treatment withdrawal.
From these results, we can deduce that Dexamethasone antithyroid-effects are
transitory and therefore do not have a significant impact on the health of the animals.
Diplôme : Magistère En ligne : ../theses/veterinaire/KEL6953.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10329 Effets de différentes doses de Dexaméthasone sur la fonction thyroïdienne chez le mouton Ouled Djellal [texte imprimé] / Narimane Kellali, Auteur ; Mustapha Kerrour, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 92 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
Sciences VétérinairesTags : Thyroïdienne Dexaméthasone Ovin fT4 fT3 Thyroid Dexamethasone Sheep Index. décimale : 636 Sciences Vétérinaires Résumé : Synthetic glucocorticosteroids are widely used in veterinary medicine for their antiinflammatory and immunosuppressive actions. However they are deemed to have
multiple side effects such as hypothyroidism.
The aim of this study was to define the effects of Dexamethasone (DEX) administered
parenterally (IM) at therapeutic doses conventionally used in the anti-inflammatory
and immunosuppressive treatments on the thyroid function in sheep.
Fifteen sheep of Ouled Djellal breeds were randomly divided into three groups of five
sheep each. The animals received an injection of Dexamethasone (DEXALONEND
solution) at a rate of 1.52 mg DEX / J for 6 days for group1 and 3.4 mg DEX / J for 6
days for group 2, the third group has served as control group and did not receive any
treatment. Blood samples taken over a period of 3 weeks were analyzed to define the
plasma levels of free thyroid hormones fT4 fT3.
It has been shown that Dexamethasone induced a significant decrease (P <0.05) of
serum fT4 and fT3 24 hours following the start of treatment. Hormone levels have
returned to their baseline values 24 hours after treatment withdrawal.
From these results, we can deduce that Dexamethasone antithyroid-effects are
transitory and therefore do not have a significant impact on the health of the animals.
Diplôme : Magistère En ligne : ../theses/veterinaire/KEL6953.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10329 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEL/6953 KEL/6953 Thèse Bibliothèque principale Thèses Disponible