| Titre : |
Caractérisations physico-chimiques et cinétique de bioactivité des biomateriaux : hydroxyapatite & verre bioactif 54S4 élaboré par fusion et par voie sol-gel |
| Type de document : |
texte imprimé |
| Auteurs : |
Fatima-Zohra Mezahi ; Univ. de Constantine, Éditeur scientifique ; A. Harabi, Directeur de thèse |
| Année de publication : |
2009 |
| Importance : |
177 f. |
| Note générale : |
01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD |
| Langues : |
Français (fre) |
| Catégories : |
Français - Anglais
Physique
|
| Tags : |
Verre Hydroxyapatite Voie fusion Procédé sol-gel Bioactivité Solution physiologique Glass Melting process Sol gel process Bioactivity الهيدروكسيدأباتيت والزجاج طريقة الإنصهار سائل-هلام النشاط الحيوي السائل فيزيولوجي |
| Index. décimale : |
530 Physique |
| Résumé : |
This work has been devoted to study the bioactive materials:
- The natural and synthetic hydroxyapatite.
- Quaternary glass 52S4: 52% SiO2- 30% CaO -14% Na2O- 4% P2O5 (wt%).
Among the main techniques used for both physical and chemical characterizations of these biomaterials are: the Induced Coupled Plasma (ICP-OES), X- Ray Diffraction (XRD), Scanning Electron Microscopy (SEM-EDS), Infra-Red spectroscopy (IR) and Nuclear Magnetic
Resonance (NMR).
The obtained results show that the hydroxyapatite bioactivity is controlled by several factors such as the density, trace elements and the second phase formation. In addition, mechanical properties optimization by adding inert oxides (ZrO2, TiO2 and Al2O3) is not always
accompanied by HA bioactivity improvement. It has been found that the presence of certain foreign oxides in the HA matrix inhibits “bone-like apatite” formation at the immerged HA surface in a Simulated Body Fluid (SBF).
As far as glasses are concerned, two synthesis routes have been used: the melting and sol-gel processes, which allow to obtain a porous glass with a large specific area. The immersion of these glasses in SBF and Phosphor Buffered Solution (PBS) has allowed to conclude that:
- the glasses synthesised by melting and sol-gel processes are bioactive, - the bioactivity kinetic is very sensitive to several factors, such as porosity, the dissolution kinetics of glasses and the ion concentrations of the immersion solution.
These work results confirm that glasses are more reactive than hydroxyapatite by carbonated apatite formation on its surface, in a very short time. |
| Diplôme : |
Doctorat en sciences |
| En ligne : |
../theses/physique/MEZ5504.pdf |
| Permalink : |
index.php?lvl=notice_display&id=3430 |
Caractérisations physico-chimiques et cinétique de bioactivité des biomateriaux : hydroxyapatite & verre bioactif 54S4 élaboré par fusion et par voie sol-gel [texte imprimé] / Fatima-Zohra Mezahi ; Univ. de Constantine, Éditeur scientifique ; A. Harabi, Directeur de thèse . - 2009 . - 177 f. 01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD Langues : Français ( fre)
| Catégories : |
Français - Anglais
Physique
|
| Tags : |
Verre Hydroxyapatite Voie fusion Procédé sol-gel Bioactivité Solution physiologique Glass Melting process Sol gel process Bioactivity الهيدروكسيدأباتيت والزجاج طريقة الإنصهار سائل-هلام النشاط الحيوي السائل فيزيولوجي |
| Index. décimale : |
530 Physique |
| Résumé : |
This work has been devoted to study the bioactive materials:
- The natural and synthetic hydroxyapatite.
- Quaternary glass 52S4: 52% SiO2- 30% CaO -14% Na2O- 4% P2O5 (wt%).
Among the main techniques used for both physical and chemical characterizations of these biomaterials are: the Induced Coupled Plasma (ICP-OES), X- Ray Diffraction (XRD), Scanning Electron Microscopy (SEM-EDS), Infra-Red spectroscopy (IR) and Nuclear Magnetic
Resonance (NMR).
The obtained results show that the hydroxyapatite bioactivity is controlled by several factors such as the density, trace elements and the second phase formation. In addition, mechanical properties optimization by adding inert oxides (ZrO2, TiO2 and Al2O3) is not always
accompanied by HA bioactivity improvement. It has been found that the presence of certain foreign oxides in the HA matrix inhibits “bone-like apatite” formation at the immerged HA surface in a Simulated Body Fluid (SBF).
As far as glasses are concerned, two synthesis routes have been used: the melting and sol-gel processes, which allow to obtain a porous glass with a large specific area. The immersion of these glasses in SBF and Phosphor Buffered Solution (PBS) has allowed to conclude that:
- the glasses synthesised by melting and sol-gel processes are bioactive, - the bioactivity kinetic is very sensitive to several factors, such as porosity, the dissolution kinetics of glasses and the ion concentrations of the immersion solution.
These work results confirm that glasses are more reactive than hydroxyapatite by carbonated apatite formation on its surface, in a very short time. |
| Diplôme : |
Doctorat en sciences |
| En ligne : |
../theses/physique/MEZ5504.pdf |
| Permalink : |
index.php?lvl=notice_display&id=3430 |
|
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