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Titre : Phytochemical and biological studies of two Algerian medicinal plants : Cytisus villosus Pourr. (Fabaceae) and Hypericum afrum Lam. (Hypericaceae) Type de document : texte imprimé Auteurs : Farida Larit, Auteur ; Samira Benyahia, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 353 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Anglais (eng) Catégories : Français - Anglais
ChimieTags : Hypericum Cytisus Secondary metabolites Total phenolics Antioxidant Cytotoxicity Antifungal Antibacterial Antimalarial Antileishmanial Activity MAO-A and MAO-B Docking Simulation Métabolites secondaires Total phénoliques Cytotoxicité Antifongique Antibactérienne Antipaludique Antileishmanienne MAO-A et MAO-B "MAO-A MAO-B Cytisus Hypericum ?????? ????????? ???????? ???? ??????? ???? ????????? ???? ???????? ???? ?????????????" Index. décimale : 540 Chimie et sciences connexes Résumé : Natural products are important sources of novel therapeutic agents. Bioactive secondary metabolites
isolated from natural sources, can act as drugs or as lead compounds for synthetic drugs. In our work, two plants
have been studied; the endemic species of Hypericum afrum Lam.(Hypericaceae) and Cytisus villosus Pourr.
(Fabaceae). Fractions of the aerial parts of these two plants have been screened in vitro for several biological
assays including cannabinoid and opioid receptors agonist assays, antifungal, antibacterial, antimalarial,
antileishmanial, antiproliferative, antioxidant, anti-inflammatory and MAO inhibition.
The chloroform, ethyl acetate and n-butanol fractions of H. afrum showed significant antioxidant activity and
potent antitrypanosomal activity against T. brucei. The n-butanol fraction of C. villosus showed highly potent
antitrypanosomal activity against T. brucei. In addition, the ethyl acetate fractions of both plants showed potent
inhibition of recombinant human monoamine oxidases (MAO-A and -B).
A bioassay-guided fractionation paradigm has been used for the isolation of bioactive compounds of these plants
and hence the subfractions that showed significant activity were further purified.
This study led to the isolation and identification of 20 compounds, three of which belonging to phloroglucinols,
terpenoids and isoflavonoids are new. The structures of the isolated compounds were elucidated through various
spectroscopic methods, including high- resolution mass spectrometry, one and two-dimensional nuclear magnetic
resonance spectroscopy.
Computational study was carried out by conformational search and docking techniques to provide insight into the
binding mode of molecules on the active site of MAO’s isoenzymes.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/LAR7157.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10430 Phytochemical and biological studies of two Algerian medicinal plants : Cytisus villosus Pourr. (Fabaceae) and Hypericum afrum Lam. (Hypericaceae) [texte imprimé] / Farida Larit, Auteur ; Samira Benyahia, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2017 . - 353 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Anglais (eng)
Catégories : Français - Anglais
ChimieTags : Hypericum Cytisus Secondary metabolites Total phenolics Antioxidant Cytotoxicity Antifungal Antibacterial Antimalarial Antileishmanial Activity MAO-A and MAO-B Docking Simulation Métabolites secondaires Total phénoliques Cytotoxicité Antifongique Antibactérienne Antipaludique Antileishmanienne MAO-A et MAO-B "MAO-A MAO-B Cytisus Hypericum ?????? ????????? ???????? ???? ??????? ???? ????????? ???? ???????? ???? ?????????????" Index. décimale : 540 Chimie et sciences connexes Résumé : Natural products are important sources of novel therapeutic agents. Bioactive secondary metabolites
isolated from natural sources, can act as drugs or as lead compounds for synthetic drugs. In our work, two plants
have been studied; the endemic species of Hypericum afrum Lam.(Hypericaceae) and Cytisus villosus Pourr.
(Fabaceae). Fractions of the aerial parts of these two plants have been screened in vitro for several biological
assays including cannabinoid and opioid receptors agonist assays, antifungal, antibacterial, antimalarial,
antileishmanial, antiproliferative, antioxidant, anti-inflammatory and MAO inhibition.
The chloroform, ethyl acetate and n-butanol fractions of H. afrum showed significant antioxidant activity and
potent antitrypanosomal activity against T. brucei. The n-butanol fraction of C. villosus showed highly potent
antitrypanosomal activity against T. brucei. In addition, the ethyl acetate fractions of both plants showed potent
inhibition of recombinant human monoamine oxidases (MAO-A and -B).
A bioassay-guided fractionation paradigm has been used for the isolation of bioactive compounds of these plants
and hence the subfractions that showed significant activity were further purified.
This study led to the isolation and identification of 20 compounds, three of which belonging to phloroglucinols,
terpenoids and isoflavonoids are new. The structures of the isolated compounds were elucidated through various
spectroscopic methods, including high- resolution mass spectrometry, one and two-dimensional nuclear magnetic
resonance spectroscopy.
Computational study was carried out by conformational search and docking techniques to provide insight into the
binding mode of molecules on the active site of MAO’s isoenzymes.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/LAR7157.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10430 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité LAR/7157 LAR/7157 Thèse Bibliothèque principale Thèses Disponible
Titre : سلوك المستهلك إتجاه المنتجات المقلدة : - دراسة حالة الجزائر- Type de document : texte imprimé Auteurs : راضية لسود ; جامعة منتوري, Editeur scientifique ; عيسى بن ناصر, Directeur de thèse Année de publication : 2009 Importance : 199 ورقة Format : 30 سم Note générale : 1 نسخة موجودة في قاعة المطالعة 1 نسخة موجودة في مخزن المكتبة المركزية+01 قرص مضغوط Langues : Arabe (ara) Catégories : Arabe
6 علم الإقتصادTags : ???? ???????? ???????? ??????? Index. décimale : 330 علم الإقتصاد En ligne : ../theses/economie/ALSO2965.pdf Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6692 سلوك المستهلك إتجاه المنتجات المقلدة : - دراسة حالة الجزائر- [texte imprimé] / راضية لسود ; جامعة منتوري, Editeur scientifique ; عيسى بن ناصر, Directeur de thèse . - 2009 . - 199 ورقة ; 30 سم.
1 نسخة موجودة في قاعة المطالعة 1 نسخة موجودة في مخزن المكتبة المركزية+01 قرص مضغوط
Langues : Arabe (ara)
Catégories : Arabe
6 علم الإقتصادTags : ???? ???????? ???????? ??????? Index. décimale : 330 علم الإقتصاد En ligne : ../theses/economie/ALSO2965.pdf Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6692 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité لسو/2965 لسو/2965 Thèse Bibliothèque principale Thèses Disponible
Titre : منهج الألباني في تصحيح الحديث وتضعيفه Type de document : texte imprimé Auteurs : عائشة غرابلي ; سلمان نصر, Directeur de thèse ; جامعة الحاج الأخضر, Editeur scientifique Année de publication : 2008 Importance : 358و. Format : 30 سم Note générale : النسخة بمخزن المكتبة هدية من جامعة باتنة Langues : Arabe (ara) Catégories : Arabe
الديانـــاتTags : ?????? ????? ???? ???????? ?????? ???? ????? ?????? Index. décimale : 200 الديانـــات Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=7070 منهج الألباني في تصحيح الحديث وتضعيفه [texte imprimé] / عائشة غرابلي ; سلمان نصر, Directeur de thèse ; جامعة الحاج الأخضر, Editeur scientifique . - 2008 . - 358و. ; 30 سم.
النسخة بمخزن المكتبة هدية من جامعة باتنة
Langues : Arabe (ara)
Catégories : Arabe
الديانـــاتTags : ?????? ????? ???? ???????? ?????? ???? ????? ?????? Index. décimale : 200 الديانـــات Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=7070 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité غرا/2727 غرا/2727 Thèse Bibliothèque principale Thèses Disponible
Titre : شركة المضاربة وتطبيقاتها المعاصرة Type de document : texte imprimé Auteurs : يمينة سلماني ; محمد محدة, Directeur de thèse ; جامعة الحاج الأخضر, Editeur scientifique Année de publication : 30سم Importance : 381 و. Format : 30سم Note générale : نسخة بمخزن المكتبة هدية من جامعة باتنة Langues : Arabe (ara) Catégories : Arabe
الديانـــاتTags : ?????? ????????? ????? ???? ???????? ???????? ????? ????? ?????? ???????? ????????? Index. décimale : 200 الديانـــات Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=7072 شركة المضاربة وتطبيقاتها المعاصرة [texte imprimé] / يمينة سلماني ; محمد محدة, Directeur de thèse ; جامعة الحاج الأخضر, Editeur scientifique . - 30سم . - 381 و. ; 30سم.
نسخة بمخزن المكتبة هدية من جامعة باتنة
Langues : Arabe (ara)
Catégories : Arabe
الديانـــاتTags : ?????? ????????? ????? ???? ???????? ???????? ????? ????? ?????? ???????? ????????? Index. décimale : 200 الديانـــات Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=7072 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité سلم/2686 سلم/2686 Thèse Bibliothèque principale Thèses Disponible
Titre : تداخل الأنواع الأدبية والفنية في الكتابة الشعرية الجزائرية المعاصرة Type de document : texte imprimé Auteurs : منى دوزة, Auteur ; محمد الصالح خرفي, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 460 ورقة. Format : 30 سم. Note générale : 2نسخ موجودة مكتبة المركزية
Langues : Arabe (ara) Catégories : Arabe
الأدب العربيTags : ????? ??????? ??????? ??????? ??????? ??????? ????????? ???????? ???? ???????? ???? ??????? ??????? ???? ????????? ???? ?????? contemporary Algerian poetic writing overlapping literary and artistic genres formation art, theatrical art cinematic art narrative art chevauchement des genres littéraires et artistiques la poésie algérienne contemporaine l'art plastique l'art dramatique et théâtral l'art cinématographie l'art récit Index. décimale : 810 أدب عربي Résumé : Poetry is one of the most popular arts for the employment of other types of art as it enters into relationships with what is close to or away from the artistic and literary types borrowed from the various tools and techniques in response to the requirements of aesthetic estrangement that works in order to promote its energies. hence came the study entitled the overlap of literary and artistic types in the writing of contemporary Algerian poetry which breed to follow the phenomenon of overlapping poetry with different types of artistic and literary and then reveal the extent of to which it benefits the modern Algerian poetry in the constructions of various artistic formations in writing and reserving the poem .
In order to reveal the fact of the quabtating ouerlap we chose the product of twenty one poems of ten poets. These writings embody models of the interplay of poetry with the four arts, formation arts, theatrical arts, cinematic arts and the narrative art, whereas the presence of on art in another ome is a technical presence of a technique or a number of technique in its structural composition have been based on the raw backgrounds of each art from its means, patterns and characteristics of the original quality to reveal the impact of eache of these arts in poetry.
In order to deepen the awareness of the poetic experiences , dealing with the artistic flutter in the creation of contomporary algerien poetic text,and to show /revealing the impact that is caused by the interfere in the produce of high poetic intrpretation we have adapted a plan that consists of five chapters in the first chapter,the study sought to understand the theories of artistic types and literary types.in this chapter we dealt the problems, concepts, standards and distinguishing features through examining the critical Arabic and western blog. The old and the recent one withe its density .this chapter tries to explore its pratical chapters through examining,descrubing, analyzing and interpreting the issue of the overlap of literary, artistic, formative, play, cinematic and narrative within the modern algerian poetry.
Accordingly, the secend chapter wich is marcked by the overlap of poetry with the plastic art to combine the culture of word with its oral communication and the culture of image through its visual communication through tesctual composition and image formatoion in the search code .in the thired chapter which is marked by the interplay of poetry with dramatic art and the art of play we distinguished between the dual text/and the presentation with their different instruments and their multiple forms of dialogue, conflict and sinography.
The fourth chapter deals with the interplay of poetry with cinematic art in the technical aspect of the camera in the contemporary algerian poetic literature through the inspiration of the technique of chips and montage as applied in the art of cinema .the last chapter escamines the interaction of poetry withe narrative art in the position of the narrator and the perspective from which his vision is determined for the event which narrates as it shours the features and other narrative elements that have constructive role in promoting poetic writing which are the characters, time, place, the event, the narratine time and the nature of the language used in completing the narration program of the poetic text.
Through these main aces, the research sought to deepen the awareness of the poetic experience by revealing the tricks of the artistic speries with their elements, patterns and different types within the proetic text, which is esctented in vitality to absorb them in search of renewable artiste energies that can eXpress their energies more dynamically without losing poetic art.
Diplôme : Doctorat en sciences En ligne : ../theses/arabe/ADOU4339.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10945 تداخل الأنواع الأدبية والفنية في الكتابة الشعرية الجزائرية المعاصرة [texte imprimé] / منى دوزة, Auteur ; محمد الصالح خرفي, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2018 . - 460 ورقة. ; 30 سم.
2نسخ موجودة مكتبة المركزية
Langues : Arabe (ara)
Catégories : Arabe
الأدب العربيTags : ????? ??????? ??????? ??????? ??????? ??????? ????????? ???????? ???? ???????? ???? ??????? ??????? ???? ????????? ???? ?????? contemporary Algerian poetic writing overlapping literary and artistic genres formation art, theatrical art cinematic art narrative art chevauchement des genres littéraires et artistiques la poésie algérienne contemporaine l'art plastique l'art dramatique et théâtral l'art cinématographie l'art récit Index. décimale : 810 أدب عربي Résumé : Poetry is one of the most popular arts for the employment of other types of art as it enters into relationships with what is close to or away from the artistic and literary types borrowed from the various tools and techniques in response to the requirements of aesthetic estrangement that works in order to promote its energies. hence came the study entitled the overlap of literary and artistic types in the writing of contemporary Algerian poetry which breed to follow the phenomenon of overlapping poetry with different types of artistic and literary and then reveal the extent of to which it benefits the modern Algerian poetry in the constructions of various artistic formations in writing and reserving the poem .
In order to reveal the fact of the quabtating ouerlap we chose the product of twenty one poems of ten poets. These writings embody models of the interplay of poetry with the four arts, formation arts, theatrical arts, cinematic arts and the narrative art, whereas the presence of on art in another ome is a technical presence of a technique or a number of technique in its structural composition have been based on the raw backgrounds of each art from its means, patterns and characteristics of the original quality to reveal the impact of eache of these arts in poetry.
In order to deepen the awareness of the poetic experiences , dealing with the artistic flutter in the creation of contomporary algerien poetic text,and to show /revealing the impact that is caused by the interfere in the produce of high poetic intrpretation we have adapted a plan that consists of five chapters in the first chapter,the study sought to understand the theories of artistic types and literary types.in this chapter we dealt the problems, concepts, standards and distinguishing features through examining the critical Arabic and western blog. The old and the recent one withe its density .this chapter tries to explore its pratical chapters through examining,descrubing, analyzing and interpreting the issue of the overlap of literary, artistic, formative, play, cinematic and narrative within the modern algerian poetry.
Accordingly, the secend chapter wich is marcked by the overlap of poetry with the plastic art to combine the culture of word with its oral communication and the culture of image through its visual communication through tesctual composition and image formatoion in the search code .in the thired chapter which is marked by the interplay of poetry with dramatic art and the art of play we distinguished between the dual text/and the presentation with their different instruments and their multiple forms of dialogue, conflict and sinography.
The fourth chapter deals with the interplay of poetry with cinematic art in the technical aspect of the camera in the contemporary algerian poetic literature through the inspiration of the technique of chips and montage as applied in the art of cinema .the last chapter escamines the interaction of poetry withe narrative art in the position of the narrator and the perspective from which his vision is determined for the event which narrates as it shours the features and other narrative elements that have constructive role in promoting poetic writing which are the characters, time, place, the event, the narratine time and the nature of the language used in completing the narration program of the poetic text.
Through these main aces, the research sought to deepen the awareness of the poetic experience by revealing the tricks of the artistic speries with their elements, patterns and different types within the proetic text, which is esctented in vitality to absorb them in search of renewable artiste energies that can eXpress their energies more dynamically without losing poetic art.
Diplôme : Doctorat en sciences En ligne : ../theses/arabe/ADOU4339.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10945 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité دوز/4339 دوز/4339 Thèse Bibliothèque principale Thèses Disponible Etude phytochimique et valorisation biologique des deux plantes, Genista quadriflora Munby (Fabaceae) et Convolvulus tricolor L. (Convolvulaceae) / Nassira Kacem
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