Résultat de la recherche
31 résultat(s) recherche sur le tag 'flavonoids' 
Visionner les documents numériques
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Interroger des sources externesRecherche et détermination structurale de métabolites secondaires de Matricaria Chamomilla (Asteraceae) / Hanane Achoub
Titre : Recherche et détermination structurale de métabolites secondaires de Matricaria Chamomilla (Asteraceae) : Etude de la phase n- butanol. Type de document : texte imprimé Auteurs : Hanane Achoub, Auteur ; Lahcene Zaiter, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 115 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Tags : Flavonoïdes matricaria chamomilla composées flavonoids Asteraceae ??????? ??????? ???????????? Index. décimale : 540 Chimie et sciences connexes Résumé :
The main purpose in this work was, the isolation and the structural détermination of the secondary metabolites of the flavonoids type from the nbutanol phase of the aerial parts of Matricaria chamomilla species belonging to the Asteraceae family.
Our choice for this species is justified by the fact that several species of the geans Matricaria are used in folk medicine for their anti-inflammatory, antibacterial, anti-ulcerative , antipyretic ,antispasmodic activities, for treatment of gastrointestinal disorders and against uterine shrinkages…
This study relates to the phytochemical investigation of the n-butanol phase of the aqueous-alcoholic extracts of the leaves and the flowers of Matricaria chamomilla. This contribution led to the isolation of seven products in the pure state, from which, we have established the structure of to products.
- Luteolin-7-O-β-glucoside.
- 5, 6, 7,3’,4’-pentahydroxyflavone-4’-O-β-D-glucoside.
The isolation and structure determenation of isolated coumpounds were based on the different spectroscopic technics such as ultraviolet, 1H NMR, 13C NMR, 2D NMR experiments (COSY, HSQC, HMBC) and mass spectrometry.
It is important to note, that 5, 6, 7, 3’,4’-pentahydroxyflavone-4’-O-β-Dglucoside is new and then ,was not described elsewhere.Diplôme : Magistère En ligne : ../theses/chimie/ACH6327.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6294 Recherche et détermination structurale de métabolites secondaires de Matricaria Chamomilla (Asteraceae) : Etude de la phase n- butanol. [texte imprimé] / Hanane Achoub, Auteur ; Lahcene Zaiter, Directeur de thèse . - constantine (Route ain el bey, Algérie) : Université Constantine 1, 2013 . - 115 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Tags : Flavonoïdes matricaria chamomilla composées flavonoids Asteraceae ??????? ??????? ???????????? Index. décimale : 540 Chimie et sciences connexes Résumé :
The main purpose in this work was, the isolation and the structural détermination of the secondary metabolites of the flavonoids type from the nbutanol phase of the aerial parts of Matricaria chamomilla species belonging to the Asteraceae family.
Our choice for this species is justified by the fact that several species of the geans Matricaria are used in folk medicine for their anti-inflammatory, antibacterial, anti-ulcerative , antipyretic ,antispasmodic activities, for treatment of gastrointestinal disorders and against uterine shrinkages…
This study relates to the phytochemical investigation of the n-butanol phase of the aqueous-alcoholic extracts of the leaves and the flowers of Matricaria chamomilla. This contribution led to the isolation of seven products in the pure state, from which, we have established the structure of to products.
- Luteolin-7-O-β-glucoside.
- 5, 6, 7,3’,4’-pentahydroxyflavone-4’-O-β-D-glucoside.
The isolation and structure determenation of isolated coumpounds were based on the different spectroscopic technics such as ultraviolet, 1H NMR, 13C NMR, 2D NMR experiments (COSY, HSQC, HMBC) and mass spectrometry.
It is important to note, that 5, 6, 7, 3’,4’-pentahydroxyflavone-4’-O-β-Dglucoside is new and then ,was not described elsewhere.Diplôme : Magistère En ligne : ../theses/chimie/ACH6327.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6294 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire
Titre : Rechercherche et détermination structurale de métabolites secondaires D'Ononis angustissima (Fabaceae) : Etude de la phase chloroforme de l'extrait hvdroalcoolique Type de document : texte imprimé Auteurs : Wassila Benabderrahmane, Auteur ; Mohamed Bouheroum, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 127 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Tags : Ononis angustissima fabaceae Flavonoides chalcone aurone flavonoids Index. décimale : 540 Chimie et sciences connexes Résumé : This work is interesded to the phytochemical study of the species Ononis angustissima belonging to the Fabaceae family.The species of this genus ,showed their wealth of bioactive secondary metabolites.
Our study, which concerns the isolation and the structural determination of flavonoids from the chloroform soluble part of the aqueous-EtOH extract of aerial parts of Ononis angustissima, constitute a contribution in this field and supplement the results obtained in our laboratory from the ethyl acetate solublte part which led to the isolation and the sructural establishment of 8 flavonoids.
The chloroform extract was submitted to separation and purification by column and thin layer chromatography on silica gel (CCM).
The isolation and structure determination of isolated compounds were based on the different chromatographic methods(UV-Vis spectroscopy data, mass spectrometry,ID RMN (1H,13C)and 2D RMN experiments(COSY,HSQC,HMBC,HMQC and NOESY)
.
This work led to the isolation in the native state of 5 compounds which were :
2',4'-Dihydroxychalcone.
2'5,',6'Trihydroxychalcone.
6-Hydroxy -aurone.
5-Hydroxy,7Metxoy-flavone.
7Hydroxy,5Metoxy-flavone.
Diplôme : Magistère En ligne : ../theses/chimie/BEN6338.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6307 Rechercherche et détermination structurale de métabolites secondaires D'Ononis angustissima (Fabaceae) : Etude de la phase chloroforme de l'extrait hvdroalcoolique [texte imprimé] / Wassila Benabderrahmane, Auteur ; Mohamed Bouheroum, Directeur de thèse . - constantine (Route ain el bey, Algérie) : Université Constantine 1, 2013 . - 127 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Tags : Ononis angustissima fabaceae Flavonoides chalcone aurone flavonoids Index. décimale : 540 Chimie et sciences connexes Résumé : This work is interesded to the phytochemical study of the species Ononis angustissima belonging to the Fabaceae family.The species of this genus ,showed their wealth of bioactive secondary metabolites.
Our study, which concerns the isolation and the structural determination of flavonoids from the chloroform soluble part of the aqueous-EtOH extract of aerial parts of Ononis angustissima, constitute a contribution in this field and supplement the results obtained in our laboratory from the ethyl acetate solublte part which led to the isolation and the sructural establishment of 8 flavonoids.
The chloroform extract was submitted to separation and purification by column and thin layer chromatography on silica gel (CCM).
The isolation and structure determination of isolated compounds were based on the different chromatographic methods(UV-Vis spectroscopy data, mass spectrometry,ID RMN (1H,13C)and 2D RMN experiments(COSY,HSQC,HMBC,HMQC and NOESY)
.
This work led to the isolation in the native state of 5 compounds which were :
2',4'-Dihydroxychalcone.
2'5,',6'Trihydroxychalcone.
6-Hydroxy -aurone.
5-Hydroxy,7Metxoy-flavone.
7Hydroxy,5Metoxy-flavone.
Diplôme : Magistère En ligne : ../theses/chimie/BEN6338.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6307 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire
Titre : Etude phytochimique et activité antioxydante de la plante Centaurea melitensis L. Type de document : texte imprimé Auteurs : Radia Ayad, Auteur ; Kamel Medjroubi, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 209 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Tags : Astéracées Centaurea melitensis L. flavonoïdes sesquiterpènes lactones activité antioxydante Asteraceae flavonoids sesquiterpene lactones antioxidant activity ???????? ????????????? ??????? ??????? ???????????? ??????????????? ?????????? Index. décimale : 540 Chimie et sciences connexes Résumé :
In this work we have been interested by secondary metabolites of the Asteraceae family. Our interest has been on the sesquiterpene lactones and flavonoids descended from the genus Centaurea. Thus a deep biographic study has established a collection of familiar and new structures of these molecules.
This study from 2005 until the end of 2012 showed that 51 species have been investigated. These works mention 174 structures variously varied for both of these metabolites, with a predominance noticed for the sesquiterpene skeleton which the majorities are guainolides.
Our phytochemical and biological experimentation on the Algerian species Centaurea melitensis L. has on one hand highlight the isolation of fourteen (14) molecules (only eleven (11) have been identified): Three germacranolides in the pure state, a mixture of two elemanolides, another mixture of two elemanes, three flavonoid aglycones and a phenolic acid.
On the other hand the working up of the antioxidant of the methanolic extract of our plant.
The determination of structures has been realised by combining the results of spectrometric and spectroscopic methods ﴾EIMS, UV, NMR-1D, 2-D﴿.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/AYA6349.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6324 Etude phytochimique et activité antioxydante de la plante Centaurea melitensis L. [texte imprimé] / Radia Ayad, Auteur ; Kamel Medjroubi, Directeur de thèse . - constantine (Route ain el bey, Algérie) : Université Constantine 1, 2013 . - 209 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Tags : Astéracées Centaurea melitensis L. flavonoïdes sesquiterpènes lactones activité antioxydante Asteraceae flavonoids sesquiterpene lactones antioxidant activity ???????? ????????????? ??????? ??????? ???????????? ??????????????? ?????????? Index. décimale : 540 Chimie et sciences connexes Résumé :
In this work we have been interested by secondary metabolites of the Asteraceae family. Our interest has been on the sesquiterpene lactones and flavonoids descended from the genus Centaurea. Thus a deep biographic study has established a collection of familiar and new structures of these molecules.
This study from 2005 until the end of 2012 showed that 51 species have been investigated. These works mention 174 structures variously varied for both of these metabolites, with a predominance noticed for the sesquiterpene skeleton which the majorities are guainolides.
Our phytochemical and biological experimentation on the Algerian species Centaurea melitensis L. has on one hand highlight the isolation of fourteen (14) molecules (only eleven (11) have been identified): Three germacranolides in the pure state, a mixture of two elemanolides, another mixture of two elemanes, three flavonoid aglycones and a phenolic acid.
On the other hand the working up of the antioxidant of the methanolic extract of our plant.
The determination of structures has been realised by combining the results of spectrometric and spectroscopic methods ﴾EIMS, UV, NMR-1D, 2-D﴿.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/AYA6349.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6324 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire
Titre : Etude phytochimique et biologique de six plantes médicinales de l'est Algerien Type de document : texte imprimé Auteurs : Salih Chibani, Auteur ; Zahia Kabouche, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 203 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Tags : Asteraceae flavonoïdes Santolina rosmarinifolia L. antioxydant antibacterien Mentha Artemisia Ferula Senecio flavonoids antioxidant antibacterial ?? ??????? ?? ????????? Index. décimale : 540 Chimie et sciences connexes Résumé : The Asteraceae family is rich of flavonoids, particularly aglycones and methoxylated. In agreement with this characteristic, our works of extraction and isolation of flavonoids of Santolina rosmarinifolia L. specie (Asteraceae), collected from Batna, led to 3 methoxylated
aglycone flavones, eupatilin, jaceosidin and salvigenin together with luteolin and a flavonol, quercetin and 7-O-glugoside derivatives of the latters.
The butanolic extract showed an excellent antioxidant activity by the use of the DPPH.
In another hand, the essential oils obtained by hydrodistillation of Santolina rosmarinifolia L., Mentha piperita, Artemisia herba-alba, Ferula communis, F. lutea and Senecio giganteus species have been analyzed by GC and GC/MS.
The essential oil of Santolina rosmarinifolia L. showed the best antibacterial activity against Escherichia coli ATCC, Escherichia coli HS, and Enterobacter sp. strains. The essential oil of dry aerial part of Mentha piperita inhibited more strongly the growth of Escherichia coli ATCC and Streptococcus sp. strains.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/CHI6434.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9460 Etude phytochimique et biologique de six plantes médicinales de l'est Algerien [texte imprimé] / Salih Chibani, Auteur ; Zahia Kabouche, Directeur de thèse . - constantine (Route ain el bey, Algérie) : Université Constantine 1, 2013 . - 203 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Tags : Asteraceae flavonoïdes Santolina rosmarinifolia L. antioxydant antibacterien Mentha Artemisia Ferula Senecio flavonoids antioxidant antibacterial ?? ??????? ?? ????????? Index. décimale : 540 Chimie et sciences connexes Résumé : The Asteraceae family is rich of flavonoids, particularly aglycones and methoxylated. In agreement with this characteristic, our works of extraction and isolation of flavonoids of Santolina rosmarinifolia L. specie (Asteraceae), collected from Batna, led to 3 methoxylated
aglycone flavones, eupatilin, jaceosidin and salvigenin together with luteolin and a flavonol, quercetin and 7-O-glugoside derivatives of the latters.
The butanolic extract showed an excellent antioxidant activity by the use of the DPPH.
In another hand, the essential oils obtained by hydrodistillation of Santolina rosmarinifolia L., Mentha piperita, Artemisia herba-alba, Ferula communis, F. lutea and Senecio giganteus species have been analyzed by GC and GC/MS.
The essential oil of Santolina rosmarinifolia L. showed the best antibacterial activity against Escherichia coli ATCC, Escherichia coli HS, and Enterobacter sp. strains. The essential oil of dry aerial part of Mentha piperita inhibited more strongly the growth of Escherichia coli ATCC and Streptococcus sp. strains.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/CHI6434.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9460 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire 
Titre : تحدید مركبات الأیض الثانوي وَ الدراسة البیولوجیة لنباتات عطریة من جنسي Salvia وَ Stachys Type de document : texte imprimé Auteurs : هشام لكحل, Auteur ; أحمد كعبوش, Directeur de thèse Année de publication : 2014 Importance : 245 ورقة. Format : 30 سم. Note générale : مذكرة دكتوراه العلوم
2نسخ موجودة في المكتبة المركزيةLangues : Arabe (ara) Tags : triterpènes saponoside phenylpropanoide flavonoides activité antioxydante antibacterienne Stachys Salvia Lamiaceae triterpenes saponin flavonoids phenylpropanoid antioxidant activity antibacterial ????? ????? ??????? ??????????? ????????? ????????? ?????? ????? ??????? ?????? ????? ????????? Index. décimale : 540 الكيمياء و العلوم ذات العلاقة Résumé : In this work, we conducted the phytochemical study and evaluated the antibacterial and antioxidant activities of plants grown in the Eastern Algerian belonging to the Lamiaceae family : Salvia argentea var. aurasiaca (Pomel) Batt. et Trab., Stachys ocymastrum (L.) Briq. et Salvia officinalis L..
The phytochemical study of the species Salvia argentea var. aurasiaca (Pomel) Batt. et Trab resulted in the isolation of 19 compounds of which 12 were described for the first time in the plant kingdom, The isolated compounds belong to six classes of secondary metabolites:
- 12 triterpenes
- 1 saponin
- 3 flavonoids
- 1 a simple phenol derivative (new for the genus)
- 1 cinamic acid derivative
- 1 phenylpropanoid ester heteroside
The structure determination of the isolated compound was carried out by physical methods such as UV-visible spectrophotometry, the high resolution mass spectrometry with electrospray (HRESIMS), the nuclear magnetic resonance spectroscopy (NMR 1H, NMR 13C, 1H-1H COSY, HSQC, HMBC, NOESY, ROESY).
In continuation of previous works on the species Stachys ocymastrum (L.) Briq. Four flavonoids have been isolated, we’ve identified two other flavonoids from the n-butanolic extract by the use of HPLC-UV analaysis in the presence of the authentic samples.
GC and GC / MS analysis of the essential oil of Salvia officinalis L. led to the identification of 35 compounds with 3 as the major components: the α-thujone (24.52%), camphor (16.86%) and 1,8-cineole (15.92%).
The Butanolic extract of Stachys ocymastrum (L.) Briq. exhibited a good antioxidant activity by the use of the DPPH method.
The essential oil of Salvia officinalis L. especially inhibited the growth of bacterial strains namely Escherichia coli ATCC 25922, Escherichia coli (HS) and Streptococcus homeolytic and showed good antioxidant activity by β-carotene bleaching methode.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/ALEK9356.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9478 تحدید مركبات الأیض الثانوي وَ الدراسة البیولوجیة لنباتات عطریة من جنسي Salvia وَ Stachys [texte imprimé] / هشام لكحل, Auteur ; أحمد كعبوش, Directeur de thèse . - 2014 . - 245 ورقة. ; 30 سم.
مذكرة دكتوراه العلوم
2نسخ موجودة في المكتبة المركزية
Langues : Arabe (ara)
Tags : triterpènes saponoside phenylpropanoide flavonoides activité antioxydante antibacterienne Stachys Salvia Lamiaceae triterpenes saponin flavonoids phenylpropanoid antioxidant activity antibacterial ????? ????? ??????? ??????????? ????????? ????????? ?????? ????? ??????? ?????? ????? ????????? Index. décimale : 540 الكيمياء و العلوم ذات العلاقة Résumé : In this work, we conducted the phytochemical study and evaluated the antibacterial and antioxidant activities of plants grown in the Eastern Algerian belonging to the Lamiaceae family : Salvia argentea var. aurasiaca (Pomel) Batt. et Trab., Stachys ocymastrum (L.) Briq. et Salvia officinalis L..
The phytochemical study of the species Salvia argentea var. aurasiaca (Pomel) Batt. et Trab resulted in the isolation of 19 compounds of which 12 were described for the first time in the plant kingdom, The isolated compounds belong to six classes of secondary metabolites:
- 12 triterpenes
- 1 saponin
- 3 flavonoids
- 1 a simple phenol derivative (new for the genus)
- 1 cinamic acid derivative
- 1 phenylpropanoid ester heteroside
The structure determination of the isolated compound was carried out by physical methods such as UV-visible spectrophotometry, the high resolution mass spectrometry with electrospray (HRESIMS), the nuclear magnetic resonance spectroscopy (NMR 1H, NMR 13C, 1H-1H COSY, HSQC, HMBC, NOESY, ROESY).
In continuation of previous works on the species Stachys ocymastrum (L.) Briq. Four flavonoids have been isolated, we’ve identified two other flavonoids from the n-butanolic extract by the use of HPLC-UV analaysis in the presence of the authentic samples.
GC and GC / MS analysis of the essential oil of Salvia officinalis L. led to the identification of 35 compounds with 3 as the major components: the α-thujone (24.52%), camphor (16.86%) and 1,8-cineole (15.92%).
The Butanolic extract of Stachys ocymastrum (L.) Briq. exhibited a good antioxidant activity by the use of the DPPH method.
The essential oil of Salvia officinalis L. especially inhibited the growth of bacterial strains namely Escherichia coli ATCC 25922, Escherichia coli (HS) and Streptococcus homeolytic and showed good antioxidant activity by β-carotene bleaching methode.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/ALEK9356.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9478 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
PermalinkPermalink
