The effect of Vitis vinifera on inflammatory bowel disease caused by hyperhomocysteinemia / Sarah Mohammedi 

Public ISBD Titre : The effect of Vitis vinifera on inflammatory bowel disease caused by hyperhomocysteinemia Type de document : texte imprimé Auteurs : Sarah Mohammedi, Auteur ; Meriem Makhlouf, Auteur ; Sakina Zerizer, Directeur de thèse Editeur : CONSTANTINE [ALGERIE] : Université Frères Mentouri Constantine Année de publication : 2015 Importance : 61 f. Format : 30 cm. Note générale : Une copie électronique PDF disponible en BUC. Langues : Anglais (eng) Catégories : Biologie:Biologie Animale Tags : Homocysteine  methionine  hyperhomocysteinemia  folate  vitamin B6  vitamin B12  IBD  VVitis vinifera. Index. décimale : 750 Biologie Animale Résumé : Homocysteine is an intermediate metabolite of methionine. Homocysteine level in plasma depends on several factors of which the most important are folate, vitamins B 6 and B 12 status and genetic polymorphism of the enzymes involved in its metabolism. Folic acid and vitamin B 12 can lower homocysteine levels. Studies suggest that moderate hyperhomocysteinemia may play a significant role in the development of cardiovascular diseases and colorectal cancer. In the present work we have studied the relationship of hyperhomocysteinemia and Inflammatory Bowel disease. The inflammatory process is evaluated by a determination of hs-CRP which was increased in groups PM and P and decreased in group of mice treated with 500mg/kg during 40days of treatment. The use of the extract of Vitis vinifera leaves during long term will induce aphrodisiac effect and antiinflammatory effect during short periode. The glutahion reduced (GSH) in treated mice with L-methionine decreased when it is compared to the other groups. Vitis vinifera is a good anti-oxidant source which protects from inflammation encountered in intestinal inflammation. We considered that the extract of Vitis vinifera leaves has a natural phytotherapy in IBD but during short period of treatment. Diplome : Master 2 Permalink : https://bu.umc.edu.dz/master/index.php?lvl=notice_display&id=5371 The effect of Vitis vinifera on inflammatory bowel disease caused by hyperhomocysteinemia [texte imprimé] / Sarah Mohammedi, Auteur ; Meriem Makhlouf, Auteur ; Sakina Zerizer, Directeur de thèse . - CONSTANTINE [ALGERIE] : Université Frères Mentouri Constantine, 2015 . - 61 f. ; 30 cm. Une copie électronique PDF disponible en BUC. Langues : Anglais (eng) Catégories : Biologie:Biologie Animale Tags : Homocysteine  methionine  hyperhomocysteinemia  folate  vitamin B6  vitamin B12  IBD  VVitis vinifera. Index. décimale : 750 Biologie Animale Résumé : Homocysteine is an intermediate metabolite of methionine. Homocysteine level in plasma depends on several factors of which the most important are folate, vitamins B 6 and B 12 status and genetic polymorphism of the enzymes involved in its metabolism. Folic acid and vitamin B 12 can lower homocysteine levels. Studies suggest that moderate hyperhomocysteinemia may play a significant role in the development of cardiovascular diseases and colorectal cancer. In the present work we have studied the relationship of hyperhomocysteinemia and Inflammatory Bowel disease. The inflammatory process is evaluated by a determination of hs-CRP which was increased in groups PM and P and decreased in group of mice treated with 500mg/kg during 40days of treatment. The use of the extract of Vitis vinifera leaves during long term will induce aphrodisiac effect and antiinflammatory effect during short periode. The glutahion reduced (GSH) in treated mice with L-methionine decreased when it is compared to the other groups. Vitis vinifera is a good anti-oxidant source which protects from inflammation encountered in intestinal inflammation. We considered that the extract of Vitis vinifera leaves has a natural phytotherapy in IBD but during short period of treatment. Diplome : Master 2 Permalink : https://bu.umc.edu.dz/master/index.php?lvl=notice_display&id=5371

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