| Titre : |
Effect of Dietary Addition of 2.5% Fenugreek on Serum Lipids and Body Fat in Rats. |
| Type de document : |
texte imprimé |
| Auteurs : |
Kawther Boucharef, Auteur ; Y Necib, Directeur de thèse |
| Editeur : |
CONSTANTINE [ALGERIE] : Université Frères Mentouri Constantine |
| Année de publication : |
2014 |
| Importance : |
58 f. |
| Format : |
30 cm. |
| Note générale : |
Une copie electronique PDF disponible au BUC |
| Langues : |
Français (fre) |
| Catégories : |
Biologie:Biochimie et Biologie Cellulaire et Moléculaire
|
| Tags : |
Fenugreek, Hypocholesterolemia, Hypotriglyceridemia, Hypoglycemia,Obesity.
Research laboratory: Departement of animals, laboratory of enzymologie, University Canstantine 1
and laboratory of biochemistry, CHU, Constantine,Proteomic Analysis and Health. |
| Index. décimale : |
730 Biochimie et biologie cellulaire |
| Résumé : |
Fenugreek is an annual herb that belongs to the family of leguminosae. It contains saponin such as
diosgenin, alkaloids as trigonelline, galactomannan, 4-hydroxyisoleucine and some flavonoids, these
coumpounds make it a potent medicinal herb. Fenugreek is used for treatment of many diseases such as
dyslipedemia, diabetes, cardiovascular diseases, cancer and for regulation of lipid metabolism. Obesity is
abnormal or excessive fat accumulation and it facilitates the development of metabolic disorders such as
diabetes, dyslipidemia, lipid oversupply, hypertension, cardiovascular diseases and cancer. These
associations between fenugreek and lipid metabolism, obesity and lipid accumulation, suggest a possible
effect of fenugreek on obesity.
This study was conducted to define the effect of 2.5% fenugreek on serum lipid and body fat
accumulation. Rats were fed for 35 days diets with or without 2.5% fenugreek. Feeding a diet containing
2.5% fenugreek caused 30% and 37% reduction in relative epididymal and perirenal adipose tissue weight
respectively, 27% decreasing in serum glucose concentration, 59%, 35% decreasing in serum triglyceride,
serum cholesterol concentrations respectively, decreasing the ratio cholesterol/HDL-cholesterol and slightly
decreasing in final body weight.
This study provided the first evidence suggesting that 2.5% fenugreek lower body fat accumulation.
Fenugreek appears to have anti-obesity effect by inhibiting adipocyte differentiation through a mechanism
involving its active compounds such as the saponin diosgenin, the alkaloid trigonelline, galactomannan and
4-Hydroxyisoleucine |
| Diplome : |
Master 2 |
| Permalink : |
https://bu.umc.edu.dz/master/index.php?lvl=notice_display&id=12916 |
Effect of Dietary Addition of 2.5% Fenugreek on Serum Lipids and Body Fat in Rats. [texte imprimé] / Kawther Boucharef, Auteur ; Y Necib, Directeur de thèse . - CONSTANTINE [ALGERIE] : Université Frères Mentouri Constantine, 2014 . - 58 f. ; 30 cm. Une copie electronique PDF disponible au BUC Langues : Français ( fre)
| Catégories : |
Biologie:Biochimie et Biologie Cellulaire et Moléculaire
|
| Tags : |
Fenugreek, Hypocholesterolemia, Hypotriglyceridemia, Hypoglycemia,Obesity.
Research laboratory: Departement of animals, laboratory of enzymologie, University Canstantine 1
and laboratory of biochemistry, CHU, Constantine,Proteomic Analysis and Health. |
| Index. décimale : |
730 Biochimie et biologie cellulaire |
| Résumé : |
Fenugreek is an annual herb that belongs to the family of leguminosae. It contains saponin such as
diosgenin, alkaloids as trigonelline, galactomannan, 4-hydroxyisoleucine and some flavonoids, these
coumpounds make it a potent medicinal herb. Fenugreek is used for treatment of many diseases such as
dyslipedemia, diabetes, cardiovascular diseases, cancer and for regulation of lipid metabolism. Obesity is
abnormal or excessive fat accumulation and it facilitates the development of metabolic disorders such as
diabetes, dyslipidemia, lipid oversupply, hypertension, cardiovascular diseases and cancer. These
associations between fenugreek and lipid metabolism, obesity and lipid accumulation, suggest a possible
effect of fenugreek on obesity.
This study was conducted to define the effect of 2.5% fenugreek on serum lipid and body fat
accumulation. Rats were fed for 35 days diets with or without 2.5% fenugreek. Feeding a diet containing
2.5% fenugreek caused 30% and 37% reduction in relative epididymal and perirenal adipose tissue weight
respectively, 27% decreasing in serum glucose concentration, 59%, 35% decreasing in serum triglyceride,
serum cholesterol concentrations respectively, decreasing the ratio cholesterol/HDL-cholesterol and slightly
decreasing in final body weight.
This study provided the first evidence suggesting that 2.5% fenugreek lower body fat accumulation.
Fenugreek appears to have anti-obesity effect by inhibiting adipocyte differentiation through a mechanism
involving its active compounds such as the saponin diosgenin, the alkaloid trigonelline, galactomannan and
4-Hydroxyisoleucine |
| Diplome : |
Master 2 |
| Permalink : |
https://bu.umc.edu.dz/master/index.php?lvl=notice_display&id=12916 |
|
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