| Titre : |
Conception, caractérisation et application des complexes à base de ligands hétérocycliques : azotés et soufrés. |
| Type de document : |
texte imprimé |
| Auteurs : |
Feriel Aouatef Sahki ép Hammoudi, Auteur ; Sofiane Bouacida, Directeur de thèse |
| Editeur : |
جامعة الإخوة منتوري قسنطينة |
| Année de publication : |
2019 |
| Importance : |
207 f. |
| Format : |
30 cm. |
| Note générale : |
Doctorat 3éme CYCLE LMD.
2 copies imprimées disponibles |
| Langues : |
Français (fre) |
| Catégories : |
Français - Anglais
Chimie
|
| Tags : |
Chimie: chimie inorganique Complexes de coordination Benzimidazole Quinoléine Benzothiazole Activité
antibactérienne Pouvoir antioxydant Structure électronique Surfaces d’Hirshfeld Coordination complexes Quinoline Antibacterial activity Antioxidant activity Electronic structure Hirshfeld Surfaces معقد تساندي كينولين بنزإميدازول بنزوثيازول نشاط مضاد للجراثيم نشاط مضاد للأكسدة البنية الالكترونية أسطح هيرشفيلد |
| Index. décimale : |
540 Chimie et sciences connexes |
| Résumé : |
This work has been devoted to the design and characterization of some new heterocyclic nitrogen and sulfur donor ligands derived from quinoline, benz-imidazole and benzothiazole, as well as their coordination complexes. The evaluation of their antibacterial and antioxidant activity was also discussed. The 2-(1H-benzo[d]imidazol-2-yl) quinoline (BQ), 2-(((1-methyl-1H-imidazol-2- ylmethyl)sulfanyl)methyl)-1H-benzo[d]ligands imidazole (MIMTMB), 2-(((1-methyl-1Himidazol- 2-yl)methyl)sulfanyl)benzo[d]thiazole (MIMTBT), as well as two other ligands previously prepared in the laboratory: The bis((1H-benzo[d]imidazol-2-yl)methyl) sulfane (BBMS) and 2-((1H-benzo[d]imidazol-2-yl)methylthio)-1H-benzo[d]imidazole (BTMB) react with the chlorides of cobalt (II), zinc (II), manganese (II), mercury (II), lead (II), copper (II), and cadmium (II) to lead to coordination complexes. The structures of the ligands and their complexes have been elucidated by IR spectroscopy, 1H NMR, 13C NMR, UV-visible, elemental analysis and single-crystal X-ray diffraction. The structural characterization by RX revealed the complex environment and the stability of the crystal structure by hydrogen bonds and π-π interactions. Theoretical calculations for some complexes were made to understand the geometry and the electronic structure of some compounds. As well as thermogravimetric analyzes that have been performed on some compounds to better understand their behavior and thermal stability. The antibacterial activity of certain ligands and complexes was evaluated against three strains: Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. As well as an evaluation of their antioxidant activity (DPPH test). |
| Note de contenu : |
Annexes. |
| Diplôme : |
Doctorat |
| En ligne : |
../theses/chimie/SAH7511.pdf |
| Format de la ressource électronique : |
pdf |
| Permalink : |
index.php?lvl=notice_display&id=11347 |
Conception, caractérisation et application des complexes à base de ligands hétérocycliques : azotés et soufrés. [texte imprimé] / Feriel Aouatef Sahki ép Hammoudi, Auteur ; Sofiane Bouacida, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2019 . - 207 f. ; 30 cm. Doctorat 3éme CYCLE LMD.
2 copies imprimées disponibles Langues : Français ( fre)
| Catégories : |
Français - Anglais
Chimie
|
| Tags : |
Chimie: chimie inorganique Complexes de coordination Benzimidazole Quinoléine Benzothiazole Activité
antibactérienne Pouvoir antioxydant Structure électronique Surfaces d’Hirshfeld Coordination complexes Quinoline Antibacterial activity Antioxidant activity Electronic structure Hirshfeld Surfaces معقد تساندي كينولين بنزإميدازول بنزوثيازول نشاط مضاد للجراثيم نشاط مضاد للأكسدة البنية الالكترونية أسطح هيرشفيلد |
| Index. décimale : |
540 Chimie et sciences connexes |
| Résumé : |
This work has been devoted to the design and characterization of some new heterocyclic nitrogen and sulfur donor ligands derived from quinoline, benz-imidazole and benzothiazole, as well as their coordination complexes. The evaluation of their antibacterial and antioxidant activity was also discussed. The 2-(1H-benzo[d]imidazol-2-yl) quinoline (BQ), 2-(((1-methyl-1H-imidazol-2- ylmethyl)sulfanyl)methyl)-1H-benzo[d]ligands imidazole (MIMTMB), 2-(((1-methyl-1Himidazol- 2-yl)methyl)sulfanyl)benzo[d]thiazole (MIMTBT), as well as two other ligands previously prepared in the laboratory: The bis((1H-benzo[d]imidazol-2-yl)methyl) sulfane (BBMS) and 2-((1H-benzo[d]imidazol-2-yl)methylthio)-1H-benzo[d]imidazole (BTMB) react with the chlorides of cobalt (II), zinc (II), manganese (II), mercury (II), lead (II), copper (II), and cadmium (II) to lead to coordination complexes. The structures of the ligands and their complexes have been elucidated by IR spectroscopy, 1H NMR, 13C NMR, UV-visible, elemental analysis and single-crystal X-ray diffraction. The structural characterization by RX revealed the complex environment and the stability of the crystal structure by hydrogen bonds and π-π interactions. Theoretical calculations for some complexes were made to understand the geometry and the electronic structure of some compounds. As well as thermogravimetric analyzes that have been performed on some compounds to better understand their behavior and thermal stability. The antibacterial activity of certain ligands and complexes was evaluated against three strains: Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. As well as an evaluation of their antioxidant activity (DPPH test). |
| Note de contenu : |
Annexes. |
| Diplôme : |
Doctorat |
| En ligne : |
../theses/chimie/SAH7511.pdf |
| Format de la ressource électronique : |
pdf |
| Permalink : |
index.php?lvl=notice_display&id=11347 |
|
Conception, caractérisation et application des complexes à base de ligands hétérocycliques
