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Partager le résultat de cette recherche Interroger des sources externesEffets de différentes doses de Dexaméthasone sur la fonction thyroïdienne chez le mouton Ouled Djellal / Narimane Kellali
Titre : Effets de différentes doses de Dexaméthasone sur la fonction thyroïdienne chez le mouton Ouled Djellal Type de document : texte imprimé Auteurs : Narimane Kellali, Auteur ; Mustapha Kerrour, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 92 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
Sciences VétérinairesTags : Thyroïdienne Dexaméthasone Ovin fT4 fT3 Thyroid Dexamethasone Sheep Index. décimale : 636 Sciences Vétérinaires Résumé : Synthetic glucocorticosteroids are widely used in veterinary medicine for their antiinflammatory and immunosuppressive actions. However they are deemed to have
multiple side effects such as hypothyroidism.
The aim of this study was to define the effects of Dexamethasone (DEX) administered
parenterally (IM) at therapeutic doses conventionally used in the anti-inflammatory
and immunosuppressive treatments on the thyroid function in sheep.
Fifteen sheep of Ouled Djellal breeds were randomly divided into three groups of five
sheep each. The animals received an injection of Dexamethasone (DEXALONEND
solution) at a rate of 1.52 mg DEX / J for 6 days for group1 and 3.4 mg DEX / J for 6
days for group 2, the third group has served as control group and did not receive any
treatment. Blood samples taken over a period of 3 weeks were analyzed to define the
plasma levels of free thyroid hormones fT4 fT3.
It has been shown that Dexamethasone induced a significant decrease (P <0.05) of
serum fT4 and fT3 24 hours following the start of treatment. Hormone levels have
returned to their baseline values 24 hours after treatment withdrawal.
From these results, we can deduce that Dexamethasone antithyroid-effects are
transitory and therefore do not have a significant impact on the health of the animals.
Diplôme : Magistère En ligne : ../theses/veterinaire/KEL6953.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10329 Effets de différentes doses de Dexaméthasone sur la fonction thyroïdienne chez le mouton Ouled Djellal [texte imprimé] / Narimane Kellali, Auteur ; Mustapha Kerrour, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 92 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
Sciences VétérinairesTags : Thyroïdienne Dexaméthasone Ovin fT4 fT3 Thyroid Dexamethasone Sheep Index. décimale : 636 Sciences Vétérinaires Résumé : Synthetic glucocorticosteroids are widely used in veterinary medicine for their antiinflammatory and immunosuppressive actions. However they are deemed to have
multiple side effects such as hypothyroidism.
The aim of this study was to define the effects of Dexamethasone (DEX) administered
parenterally (IM) at therapeutic doses conventionally used in the anti-inflammatory
and immunosuppressive treatments on the thyroid function in sheep.
Fifteen sheep of Ouled Djellal breeds were randomly divided into three groups of five
sheep each. The animals received an injection of Dexamethasone (DEXALONEND
solution) at a rate of 1.52 mg DEX / J for 6 days for group1 and 3.4 mg DEX / J for 6
days for group 2, the third group has served as control group and did not receive any
treatment. Blood samples taken over a period of 3 weeks were analyzed to define the
plasma levels of free thyroid hormones fT4 fT3.
It has been shown that Dexamethasone induced a significant decrease (P <0.05) of
serum fT4 and fT3 24 hours following the start of treatment. Hormone levels have
returned to their baseline values 24 hours after treatment withdrawal.
From these results, we can deduce that Dexamethasone antithyroid-effects are
transitory and therefore do not have a significant impact on the health of the animals.
Diplôme : Magistère En ligne : ../theses/veterinaire/KEL6953.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10329 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEL/6953 KEL/6953 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude préliminaire d’une carence hydrique et alimentaire chez le rat : Effets physiologiques et endocrines Type de document : texte imprimé Auteurs : Fatiha Khouni, Auteur ; Abedenacer Boudah, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2014 Importance : 86 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : carence hydrique carence alimentaire FT3 FT4 TSH water stress diet deficiency الحرمان من الطعام الحرمان من الماء هرمون المنبه الغدة الدرقية هرموني الغدة الدرقية Index. décimale : 570 Sciences de la vie. Biologie Résumé :
The aim of our study was to evaluate the effect of water deprivation, food deprivation and their combination for three days on the metabolic and endocrine status in rats.
The level of total lipids and triglycerides were significantly reduced, however the level of total cholesterol, HDL cholesterol and LDL cholesterol was increased in all groups.
The results of urine tests (kaliuresis, natriuresis, proteinuria) showed a significant signs of dehydration with a significant increase in total protein in dehydrated rats.
Thyroid failure reflected by a decrease in the level of plasma FT4 and FT3 was noted after dehydration, malnutrition and their association. A significant decrease in plasma TSH was observed in malnourished rats and dehydrated and malnourished rats; this level was decreased but not significantly in dehydrated rats.
In our study, we showed that the water and food deprivation or altogether activate hepatic glycogenolysis, muscle lipid oxidation. On the other hand, it seems that nutritional stress modifies the pituitary-thyroid axis through mechanisms different from those of osmotic stress.Diplôme : Magistère En ligne : ../theses/biologie/KHO6641.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9774 Etude préliminaire d’une carence hydrique et alimentaire chez le rat : Effets physiologiques et endocrines [texte imprimé] / Fatiha Khouni, Auteur ; Abedenacer Boudah, Directeur de thèse . - constantine [Algérie] : Université Constantine 1, 2014 . - 86 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : carence hydrique carence alimentaire FT3 FT4 TSH water stress diet deficiency الحرمان من الطعام الحرمان من الماء هرمون المنبه الغدة الدرقية هرموني الغدة الدرقية Index. décimale : 570 Sciences de la vie. Biologie Résumé :
The aim of our study was to evaluate the effect of water deprivation, food deprivation and their combination for three days on the metabolic and endocrine status in rats.
The level of total lipids and triglycerides were significantly reduced, however the level of total cholesterol, HDL cholesterol and LDL cholesterol was increased in all groups.
The results of urine tests (kaliuresis, natriuresis, proteinuria) showed a significant signs of dehydration with a significant increase in total protein in dehydrated rats.
Thyroid failure reflected by a decrease in the level of plasma FT4 and FT3 was noted after dehydration, malnutrition and their association. A significant decrease in plasma TSH was observed in malnourished rats and dehydrated and malnourished rats; this level was decreased but not significantly in dehydrated rats.
In our study, we showed that the water and food deprivation or altogether activate hepatic glycogenolysis, muscle lipid oxidation. On the other hand, it seems that nutritional stress modifies the pituitary-thyroid axis through mechanisms different from those of osmotic stress.Diplôme : Magistère En ligne : ../theses/biologie/KHO6641.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9774 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KHO/6641 KHO/6641 Thèse Bibliothèque principale Thèses Disponible Documents numériques
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