| Titre : |
Nouvelles voies de synthèse des hétérocycles et des dipeptides à tête prosthétique |
| Type de document : |
texte imprimé |
| Auteurs : |
Imane Tebabel, Auteur ; Taoues Boumoud, Directeur de thèse |
| Editeur : |
جامعة الإخوة منتوري قسنطينة |
| Année de publication : |
2017 |
| Importance : |
206 f. |
| Format : |
30 cm. |
| Note générale : |
2 copies imprimées disponibles
|
| Langues : |
Français (fre) |
| Catégories : |
Français - Anglais
Chimie
|
| Tags : |
Dihydropyrimidinones DHPMs liquide ionique thiazolopyrimidinones oxadiazolopyrimidines dipepetide Biginelli et pseudo Hantzsch nitrate d'ammonium ionic liquid Biginelli and Hantzsch-like مشتقات الدي هيدروبيريميدينون DHPM السائل الأيوني من ثیازولو[2,3-a] بیریمیدین3- (H25-
بنزیلدینثیازولو[2,3-a]بیریمیدین الأ كسادزول 3-سيانوبيريدون ثنائي الببتید |
| Index. décimale : |
540 Chimie et sciences connexes |
| Résumé : |
In the first chapter, we developed a novel catalytic synthesis of 3,4-
dihydropyrimidinones via Biginelli reaction in the presence of a bronsted ionic liquid [H-val]
HSO4 as the reaction medium. Then, we performed the synthesis of thiazolo[3,2-
a]pyrimidin-3(5H)-ones via Hantzsch thiazoles synthesis using bromide ethylacetoacetate as
an alkylatig agent in refluxed acetone, this novel method allowed to prepare these fused
heterocyclic compounds in good yields. Lability of hydrogens in previous derivatives allowed
to prepare new 2-benzilidénethiazolo[3,2-a]pyrimidin-3(5H)-ones via two methods: divergent
and convergent from DHPMs as starting materials.
In addition in the second chapter, we were interested in the development of novel
synthesis of 2-cyanopyridones via Hantzsch-like reaction using ammonium nitrate instead of the usually used ammonium acetate. Then we carried out several consecutive reactions on
these heterocyclic compounds to achieve the desired products: oxadiazolopyridines.
In the third chapter, we have prepared some dipeptide N-cyanopyridines from
cyanopyridines by carrying out some consecutive reactions.
|
| Diplôme : |
Doctorat en sciences |
| En ligne : |
../theses/chimie/TEB7138.pdf |
| Format de la ressource électronique : |
pdf |
| Permalink : |
index.php?lvl=notice_display&id=10464 |
Nouvelles voies de synthèse des hétérocycles et des dipeptides à tête prosthétique [texte imprimé] / Imane Tebabel, Auteur ; Taoues Boumoud, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2017 . - 206 f. ; 30 cm. 2 copies imprimées disponibles
Langues : Français ( fre)
| Catégories : |
Français - Anglais
Chimie
|
| Tags : |
Dihydropyrimidinones DHPMs liquide ionique thiazolopyrimidinones oxadiazolopyrimidines dipepetide Biginelli et pseudo Hantzsch nitrate d'ammonium ionic liquid Biginelli and Hantzsch-like مشتقات الدي هيدروبيريميدينون DHPM السائل الأيوني من ثیازولو[2,3-a] بیریمیدین3- (H25-
بنزیلدینثیازولو[2,3-a]بیریمیدین الأ كسادزول 3-سيانوبيريدون ثنائي الببتید |
| Index. décimale : |
540 Chimie et sciences connexes |
| Résumé : |
In the first chapter, we developed a novel catalytic synthesis of 3,4-
dihydropyrimidinones via Biginelli reaction in the presence of a bronsted ionic liquid [H-val]
HSO4 as the reaction medium. Then, we performed the synthesis of thiazolo[3,2-
a]pyrimidin-3(5H)-ones via Hantzsch thiazoles synthesis using bromide ethylacetoacetate as
an alkylatig agent in refluxed acetone, this novel method allowed to prepare these fused
heterocyclic compounds in good yields. Lability of hydrogens in previous derivatives allowed
to prepare new 2-benzilidénethiazolo[3,2-a]pyrimidin-3(5H)-ones via two methods: divergent
and convergent from DHPMs as starting materials.
In addition in the second chapter, we were interested in the development of novel
synthesis of 2-cyanopyridones via Hantzsch-like reaction using ammonium nitrate instead of the usually used ammonium acetate. Then we carried out several consecutive reactions on
these heterocyclic compounds to achieve the desired products: oxadiazolopyridines.
In the third chapter, we have prepared some dipeptide N-cyanopyridines from
cyanopyridines by carrying out some consecutive reactions.
|
| Diplôme : |
Doctorat en sciences |
| En ligne : |
../theses/chimie/TEB7138.pdf |
| Format de la ressource électronique : |
pdf |
| Permalink : |
index.php?lvl=notice_display&id=10464 |
|
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