Résultat de la recherche
5 recherche sur le tag
'ionic liquid' 
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Interroger des sources externesLes liquides ioniques dans la réaction d’hétéro-cyclisation intramoléculaire de 2-aminochalcones et 2-époxychalcones / Meryem Chelghoum
Titre : Les liquides ioniques dans la réaction d’hétéro-cyclisation intramoléculaire de 2-aminochalcones et 2-époxychalcones : Synthése et évaluation biologique de dérivés de l’imidazole quaternairisés hautement fonctionnalisés. Type de document : texte imprimé Auteurs : Meryem Chelghoum, Auteur ; Ali Belfaitah, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 165 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie: chimie organique Liquides ioniques Aza-analogues de flavonoïdes Cyclisation intramoléculaire Imidazole O834 Fonctionnalisation Sels d’imidazolium Activité biologique ionic liquid intramolecular hetero-cyclization imidazolium salt antibacterial activity سوائل أيونية مشابهات الفلافونويدات تفاعل حرلقي داخل الجزيء ايميدازول املاح ايميدازول نشاط البيولوجي Index. décimale : 540 Chimie et sciences connexes Résumé :
Two distinct themes were discussed during this thesis. The first concerns the synthesis and the use of ionic liquids in the intramolecular hetero-cyclization reaction of 2-aminochalcones and 1,2-epoxy-2-aminochalcones, while the second relates to the preparation and evaluation of antibacterial activity of quaternized poly-functionalized imidazolium salts. In the first part dedicated (reserved) to the isomerization reaction of 2-aminochalcones and 2- aminochalcones epoxides in ionic liquid environment, we have shown that the reaction proceeds correctly, and it is applicable to a wide range of substrates, without the use of an additional catalyst. the cyclization of The derivatives of (E) -1- (2-aminophenyl) -3-phenylpropen-2- en-1-one were tested in Three ionic liquids [bPy] [BF4], [bmim] [BF4] and [bmim] [PF6], among these [bmim] [BF4] is the most efficient (ratio LI / substrate: 10/1, temperature: 150 ° C, reaction time: 2.5 h). The 2-aryl-2,3-dihydroquinolin-4 (1H) -ones have been obtained with satisfactory yields (70-92%) in ionic liquid [bmim] [BF4], the (this) latter is recyclable three times with a slight decrease in its catalytic activity (83 → 64%). We also reported a practical and effective protocol for the synthesis of 2-aryl-3-hydroxy-1,2,3,4- tetrahydroquinolin-4 (1H) -ones by an intramolecular cyclization reaction of epoxyde 2- aminochalcone in ionic liquid at 120 ° C (LI ratio / substrate: 5/1, temperature: 120 ° C, reaction time: 6 h) of the four ionic liquids investigated, [bmim] [OTf] gave the best results in terms of cyclized product yield (35-93%). The structures of the compounds prepared were elucidated by the usual spectroscopic methods (IR, 1H NMR and C-13), and other elemental analysis and Xray diffraction for some of them. In the second part, a whole series of highly functionalized imidazolium salt derivatives were prepared (12 compounds) and their structures elucidated by the usual spectroscopic methods (IR, 1H NMR and C-13) and by X-ray diffraction for some of them. Most of these compounds were evaluated for their inhibitory capacity against four pathogenic strains: three Gramnegative (Escherichia coli, Salmonella thipymurium and Pseudomonas aeruginosa) and one Gram-positive (Staphylococcus aureus) using two methods: the inhibition zone and the determination of the minimum inhibitory concentration (MIC). The MIC results shows that iodine derivatives have inhibitory activity against Gram-negative strains, superior to brominated derivatives and compounds bearing a nitro group. Staphylococcus aureus (Grampositive bacteria) are significantly less sensitive to the action of the substrates used.
Note de contenu :
Annexes.Diplôme : Doctorat En ligne : ../theses/chimie/CHE7406.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11058 Les liquides ioniques dans la réaction d’hétéro-cyclisation intramoléculaire de 2-aminochalcones et 2-époxychalcones : Synthése et évaluation biologique de dérivés de l’imidazole quaternairisés hautement fonctionnalisés. [texte imprimé] / Meryem Chelghoum, Auteur ; Ali Belfaitah, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 165 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie: chimie organique Liquides ioniques Aza-analogues de flavonoïdes Cyclisation intramoléculaire Imidazole O834 Fonctionnalisation Sels d’imidazolium Activité biologique ionic liquid intramolecular hetero-cyclization imidazolium salt antibacterial activity سوائل أيونية مشابهات الفلافونويدات تفاعل حرلقي داخل الجزيء ايميدازول املاح ايميدازول نشاط البيولوجي Index. décimale : 540 Chimie et sciences connexes Résumé :
Two distinct themes were discussed during this thesis. The first concerns the synthesis and the use of ionic liquids in the intramolecular hetero-cyclization reaction of 2-aminochalcones and 1,2-epoxy-2-aminochalcones, while the second relates to the preparation and evaluation of antibacterial activity of quaternized poly-functionalized imidazolium salts. In the first part dedicated (reserved) to the isomerization reaction of 2-aminochalcones and 2- aminochalcones epoxides in ionic liquid environment, we have shown that the reaction proceeds correctly, and it is applicable to a wide range of substrates, without the use of an additional catalyst. the cyclization of The derivatives of (E) -1- (2-aminophenyl) -3-phenylpropen-2- en-1-one were tested in Three ionic liquids [bPy] [BF4], [bmim] [BF4] and [bmim] [PF6], among these [bmim] [BF4] is the most efficient (ratio LI / substrate: 10/1, temperature: 150 ° C, reaction time: 2.5 h). The 2-aryl-2,3-dihydroquinolin-4 (1H) -ones have been obtained with satisfactory yields (70-92%) in ionic liquid [bmim] [BF4], the (this) latter is recyclable three times with a slight decrease in its catalytic activity (83 → 64%). We also reported a practical and effective protocol for the synthesis of 2-aryl-3-hydroxy-1,2,3,4- tetrahydroquinolin-4 (1H) -ones by an intramolecular cyclization reaction of epoxyde 2- aminochalcone in ionic liquid at 120 ° C (LI ratio / substrate: 5/1, temperature: 120 ° C, reaction time: 6 h) of the four ionic liquids investigated, [bmim] [OTf] gave the best results in terms of cyclized product yield (35-93%). The structures of the compounds prepared were elucidated by the usual spectroscopic methods (IR, 1H NMR and C-13), and other elemental analysis and Xray diffraction for some of them. In the second part, a whole series of highly functionalized imidazolium salt derivatives were prepared (12 compounds) and their structures elucidated by the usual spectroscopic methods (IR, 1H NMR and C-13) and by X-ray diffraction for some of them. Most of these compounds were evaluated for their inhibitory capacity against four pathogenic strains: three Gramnegative (Escherichia coli, Salmonella thipymurium and Pseudomonas aeruginosa) and one Gram-positive (Staphylococcus aureus) using two methods: the inhibition zone and the determination of the minimum inhibitory concentration (MIC). The MIC results shows that iodine derivatives have inhibitory activity against Gram-negative strains, superior to brominated derivatives and compounds bearing a nitro group. Staphylococcus aureus (Grampositive bacteria) are significantly less sensitive to the action of the substrates used.
Note de contenu :
Annexes.Diplôme : Doctorat En ligne : ../theses/chimie/CHE7406.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11058 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité CHE/7406 CHE/7406 Thèse Bibliothèque principale Thèses Disponible
Titre : Photodégradation du chlorure de 1-hexyl-3- methylimidazolium en milieu aqueux homogène et hétérogène. Type de document : texte imprimé Auteurs : Ameur Boutiti, Auteur ; Razika Zouaghi, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 123 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Photodégradation Liquide ionique Procédé d’Oxydation Avancée H2O2/UV S2O82–/UV TiO2/UV Photodegradation Ionic liquid Advanced Oxidation Processes الهدم الضوئي السائل الأيوني طرق الأكسدة Index. décimale : 540 Chimie et sciences connexes Résumé : 1-hexyl-3-methylimidazolium chloride (HMImCl) removal from aqueous solution has been achieved by different advanced oxidation processes (AOPs).
HMImCl direct photolysis at 254 nm showed that oxygen mainly intervenes to give O2–·, it can then react with water to form hydrogen peroxide, capable to photolyze and lead to the formation of radicals HO•. On the other hand, singlet oxygen does not participate in the oxidation reaction.
HMImCl degradation rate is appreciably increased by combining the strong oxidant H2O2 with UV light. The H2O2/UV process efficiency is enhanced by increasing H2O2 concentration up to a limit value imposed by self-quenching reactions. High alkalinity favors the disappearance while current inorganic anions chlorides, in acidic medium, inhibit it. Very similar results are obtained with S2O82-/UV process with, in particular, a rate that increases up to a limiting value of the oxidant concentration.
The reaction rate constants of the hydroxyl radicals determined for the two ionic liquids studied, transcribe the high reactivity and the speed of reaction of hydroxyl radicals on ionic liquid. The reaction rate constant of hydroxyl radicals on HMImCl is the same whatever the concentration of HMImCl Heterogeneous photocatalysis on TiO2 proved to be efficient to degrade HMImCl. The process is further improved by H2O2 or S2O82- addition up to an optimum but inhibited by anion chloride in acidic medium. The process is adequately described by the LangmuirHinshelwood kinetic model.
Selective heterogeneous photocatalysis of HMImCl in presence of benzoic acid has demonstrated that benzoic acid affect HMImCl’s degradation. A good selectivity was obtained in acidic medium, where only benzoic acid has been degraded.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/BOU7188.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10750 Photodégradation du chlorure de 1-hexyl-3- methylimidazolium en milieu aqueux homogène et hétérogène. [texte imprimé] / Ameur Boutiti, Auteur ; Razika Zouaghi, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 123 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Photodégradation Liquide ionique Procédé d’Oxydation Avancée H2O2/UV S2O82–/UV TiO2/UV Photodegradation Ionic liquid Advanced Oxidation Processes الهدم الضوئي السائل الأيوني طرق الأكسدة Index. décimale : 540 Chimie et sciences connexes Résumé : 1-hexyl-3-methylimidazolium chloride (HMImCl) removal from aqueous solution has been achieved by different advanced oxidation processes (AOPs).
HMImCl direct photolysis at 254 nm showed that oxygen mainly intervenes to give O2–·, it can then react with water to form hydrogen peroxide, capable to photolyze and lead to the formation of radicals HO•. On the other hand, singlet oxygen does not participate in the oxidation reaction.
HMImCl degradation rate is appreciably increased by combining the strong oxidant H2O2 with UV light. The H2O2/UV process efficiency is enhanced by increasing H2O2 concentration up to a limit value imposed by self-quenching reactions. High alkalinity favors the disappearance while current inorganic anions chlorides, in acidic medium, inhibit it. Very similar results are obtained with S2O82-/UV process with, in particular, a rate that increases up to a limiting value of the oxidant concentration.
The reaction rate constants of the hydroxyl radicals determined for the two ionic liquids studied, transcribe the high reactivity and the speed of reaction of hydroxyl radicals on ionic liquid. The reaction rate constant of hydroxyl radicals on HMImCl is the same whatever the concentration of HMImCl Heterogeneous photocatalysis on TiO2 proved to be efficient to degrade HMImCl. The process is further improved by H2O2 or S2O82- addition up to an optimum but inhibited by anion chloride in acidic medium. The process is adequately described by the LangmuirHinshelwood kinetic model.
Selective heterogeneous photocatalysis of HMImCl in presence of benzoic acid has demonstrated that benzoic acid affect HMImCl’s degradation. A good selectivity was obtained in acidic medium, where only benzoic acid has been degraded.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/BOU7188.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10750 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BOU/7188 BOU/7188 Thèse Bibliothèque principale Thèses Disponible
Titre : Synthèse, caractérisation et évaluation biologique De nouveaux dérivés hétérocycliques : 1,8-naphthyridines, gem-bisphosphonates et 4h-pyranes. Type de document : texte imprimé Auteurs : Mohamed Abdennour Redouane, Auteur ; N. Khiri-Meribout, Directeur de thèse ; M. Lecouvey, Directeur de thèse Mention d'édition : 03/03/2020 Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2020 Importance : 204 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie: Chimie Organique [1,8]-naphthyridines pyrrolidines gem-bisphosphonates 4H-pyranes liquide ionique cycloaddition 1,3-dipolaire Click Chemistry réaction multicomposants inhibiteur d'AChE anti-Alzheimer anti-oxydant inhibiteur de FPPS voie mévalonate Zolédronate anti-cancer ionic liquid 1,3-dipolaire cycloaddition multi component reaction AChE inhibitor anti-oxidant FPPS inhibitor mevalonate pathway Zoledronate anti cancer [-]1,8النفثريدينات البيروليدين ثنائية الفسفونات المتجاورة -4ىيدرو بيران السائل الأيوني اضافة
حلقية ثنائية القطب- 1,3التف اعلات متعددة المركبات مثبطات استيل كولين إستراز مضادات الأكسدة مثبطات FPPS
مسار الميف الونات زوليدرونات مضاد للسرطانIndex. décimale : 540 Chimie et sciences connexes Résumé :
In this manuscript, subdivided into three chapters, we are interested in the development of simple and effective new approaches for the synthesis of new functional and structural diversified heterocyclic and poly-heterocyclic systems, which represent potential biological activities. In the first chapter, we proceeded to the synthesis of the new [1,8] -naphthyridines derivatives and their tetracyclic analogs by the development of an efficient multi-step synthesis strategy. AChE and BuChE inhibition potency of synthesized products was evaluated in vitro as well as their antioxidant power. Analysis of obtained results as well as an additional study carried out by Molecular Doking confirmed the effectiveness of these molecules, specially compound 4, as multi-target agents for the treatment of AD. In the second chapter, we focused on the synthesis of new Zoledronate analogs, with a variously substituted triazole motif, via click chemistry reactions. These new gembisphosphonate derivatives was synthesized for the purpose of designing compounds with high FPPS inhibiting potency, as well as good passive penetration through the cancer cell’s membrane. The last chapter was devoted to an exclusive study comparing the catalytic efficiency of a series of different synthesized pyridinium, phosphonium or imidazolium based ionic liquids, in the synthesis of a varied range of 4H-pyran derivatives by one pot Biginelli-like multi component reaction.Diplôme : Doctorat En ligne : ../theses/chimie/RED7711.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11545 Synthèse, caractérisation et évaluation biologique De nouveaux dérivés hétérocycliques : 1,8-naphthyridines, gem-bisphosphonates et 4h-pyranes. [texte imprimé] / Mohamed Abdennour Redouane, Auteur ; N. Khiri-Meribout, Directeur de thèse ; M. Lecouvey, Directeur de thèse . - 03/03/2020 . - جامعة الإخوة منتوري قسنطينة, 2020 . - 204 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie: Chimie Organique [1,8]-naphthyridines pyrrolidines gem-bisphosphonates 4H-pyranes liquide ionique cycloaddition 1,3-dipolaire Click Chemistry réaction multicomposants inhibiteur d'AChE anti-Alzheimer anti-oxydant inhibiteur de FPPS voie mévalonate Zolédronate anti-cancer ionic liquid 1,3-dipolaire cycloaddition multi component reaction AChE inhibitor anti-oxidant FPPS inhibitor mevalonate pathway Zoledronate anti cancer [-]1,8النفثريدينات البيروليدين ثنائية الفسفونات المتجاورة -4ىيدرو بيران السائل الأيوني اضافة
حلقية ثنائية القطب- 1,3التف اعلات متعددة المركبات مثبطات استيل كولين إستراز مضادات الأكسدة مثبطات FPPS
مسار الميف الونات زوليدرونات مضاد للسرطانIndex. décimale : 540 Chimie et sciences connexes Résumé :
In this manuscript, subdivided into three chapters, we are interested in the development of simple and effective new approaches for the synthesis of new functional and structural diversified heterocyclic and poly-heterocyclic systems, which represent potential biological activities. In the first chapter, we proceeded to the synthesis of the new [1,8] -naphthyridines derivatives and their tetracyclic analogs by the development of an efficient multi-step synthesis strategy. AChE and BuChE inhibition potency of synthesized products was evaluated in vitro as well as their antioxidant power. Analysis of obtained results as well as an additional study carried out by Molecular Doking confirmed the effectiveness of these molecules, specially compound 4, as multi-target agents for the treatment of AD. In the second chapter, we focused on the synthesis of new Zoledronate analogs, with a variously substituted triazole motif, via click chemistry reactions. These new gembisphosphonate derivatives was synthesized for the purpose of designing compounds with high FPPS inhibiting potency, as well as good passive penetration through the cancer cell’s membrane. The last chapter was devoted to an exclusive study comparing the catalytic efficiency of a series of different synthesized pyridinium, phosphonium or imidazolium based ionic liquids, in the synthesis of a varied range of 4H-pyran derivatives by one pot Biginelli-like multi component reaction.Diplôme : Doctorat En ligne : ../theses/chimie/RED7711.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11545 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité RED/7711 RED/7711 Thèse Bibliothèque principale Thèses Disponible
Titre : Photodegradation d’un liquide ionique a base de cation pyridinium en solution aqueuse homogene et heterogene. Type de document : texte imprimé Auteurs : Oualida Nour El Houda Kaabeche, Auteur ; Razika Zouaghi, Auteur Mention d'édition : 24/10/2019 Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2019 Importance : 196 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie: Chimie Analytique et Environnement Liquide ionique Photodégradation Procédés d’Oxydation Avancée Radicaux
hydroxyle Photocatalyse Ionic liquid Photodegradation Advanced oxidation processes Hydroxyl radicals Photocatalysis السائل الأيوني التحلل الضوئي عمليات الأكسدة المتقدمة جذور الهيدروكسل التحفيز الضوئيIndex. décimale : 540 Chimie et sciences connexes Résumé : This study focused on the application of photochemical processes (direct photolysis and advanced oxidation processes) in the degradation of an ionic liquid; 1-hexylpyridinium bromide (HPyBr) in aqueous solution. These experiments were conducted in homogeneous phase and in heterogeneous phase. In homogeneous medium, the degradation of HPyBr was studied by different photochemical processes (UV254 nm, UV365 nm, solar irradiation and H2O2/UV254 nm) and by Fenton reagent (Fe2+/H2O2) and photo-Fenton (Fe2+/H2O2 /UV365 nm).
Various physico-chemical parameters have been tested in order to optimize the efficiency of these processes. The comparison of the performances of the various processes studied shows that H2O2/UV254 nm and Fe2+/H2O2/UV365 nm processes are the most efficient. In heterogeneous medium, two metal oxides such as ZnO and TiO2 p25 Degussa were used to compare their photoactivity on the degradation and mineralization of HPyBr. The results obtained show that the percentage of HPyBr adsorption is negligible in the presence of both catalysts. The photocatalytic degradation tests of HPyBr showed that ZnO/UV system was more efficient than the TiO2/UV system, and the disappearance kinetic of HPyBr is correctly described by the Langmuir-Hinshelwood model. The influence of the experimental parameters on the rate of degradation (substrate concentration, catalyst concentrations, pH, the addition of hydrogen peroxide, humic substances, inorganic ions, etc.) was studied. The significant inhibition of the photocatalytic reaction by the addition of chemical scavengers such as isopropanol and triethanolamine confirms that the major pathway for the degradation of HPyBr is due to the hydroxyl •OH radicals formed by irradiation of the photocatalyst surface. The oxidation (COD) and the mineralization (TOC) decrease according to the treatment but more slowly than the degradation, this confirms that the treatment of HPyBr by the photocatalytic process leads to the decrease of the organic matter content, however it requires a relatively slow processing time. In order to verify the feasibility of the photocatalytic process in the environment, both systems were studied under solar irradiation. The results show that the efficiency at this scale is greater than artificial radiation.
Diplôme : Doctorat En ligne : ../theses/chimie/KAA7572.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11410 Photodegradation d’un liquide ionique a base de cation pyridinium en solution aqueuse homogene et heterogene. [texte imprimé] / Oualida Nour El Houda Kaabeche, Auteur ; Razika Zouaghi, Auteur . - 24/10/2019 . - جامعة الإخوة منتوري قسنطينة, 2019 . - 196 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie: Chimie Analytique et Environnement Liquide ionique Photodégradation Procédés d’Oxydation Avancée Radicaux
hydroxyle Photocatalyse Ionic liquid Photodegradation Advanced oxidation processes Hydroxyl radicals Photocatalysis السائل الأيوني التحلل الضوئي عمليات الأكسدة المتقدمة جذور الهيدروكسل التحفيز الضوئيIndex. décimale : 540 Chimie et sciences connexes Résumé : This study focused on the application of photochemical processes (direct photolysis and advanced oxidation processes) in the degradation of an ionic liquid; 1-hexylpyridinium bromide (HPyBr) in aqueous solution. These experiments were conducted in homogeneous phase and in heterogeneous phase. In homogeneous medium, the degradation of HPyBr was studied by different photochemical processes (UV254 nm, UV365 nm, solar irradiation and H2O2/UV254 nm) and by Fenton reagent (Fe2+/H2O2) and photo-Fenton (Fe2+/H2O2 /UV365 nm).
Various physico-chemical parameters have been tested in order to optimize the efficiency of these processes. The comparison of the performances of the various processes studied shows that H2O2/UV254 nm and Fe2+/H2O2/UV365 nm processes are the most efficient. In heterogeneous medium, two metal oxides such as ZnO and TiO2 p25 Degussa were used to compare their photoactivity on the degradation and mineralization of HPyBr. The results obtained show that the percentage of HPyBr adsorption is negligible in the presence of both catalysts. The photocatalytic degradation tests of HPyBr showed that ZnO/UV system was more efficient than the TiO2/UV system, and the disappearance kinetic of HPyBr is correctly described by the Langmuir-Hinshelwood model. The influence of the experimental parameters on the rate of degradation (substrate concentration, catalyst concentrations, pH, the addition of hydrogen peroxide, humic substances, inorganic ions, etc.) was studied. The significant inhibition of the photocatalytic reaction by the addition of chemical scavengers such as isopropanol and triethanolamine confirms that the major pathway for the degradation of HPyBr is due to the hydroxyl •OH radicals formed by irradiation of the photocatalyst surface. The oxidation (COD) and the mineralization (TOC) decrease according to the treatment but more slowly than the degradation, this confirms that the treatment of HPyBr by the photocatalytic process leads to the decrease of the organic matter content, however it requires a relatively slow processing time. In order to verify the feasibility of the photocatalytic process in the environment, both systems were studied under solar irradiation. The results show that the efficiency at this scale is greater than artificial radiation.
Diplôme : Doctorat En ligne : ../theses/chimie/KAA7572.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11410 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KAA/7572 KAA/7572 Thèse Bibliothèque principale Thèses Disponible
Titre : Nouvelles voies de synthèse des hétérocycles et des dipeptides à tête prosthétique Type de document : texte imprimé Auteurs : Imane Tebabel, Auteur ; Taoues Boumoud, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 206 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Dihydropyrimidinones DHPMs liquide ionique thiazolopyrimidinones oxadiazolopyrimidines dipepetide Biginelli et pseudo Hantzsch nitrate d'ammonium ionic liquid Biginelli and Hantzsch-like مشتقات الدي هيدروبيريميدينون DHPM السائل الأيوني من ثیازولو[2,3-a] بیریمیدین3- (H25-
بنزیلدینثیازولو[2,3-a]بیریمیدین الأ كسادزول 3-سيانوبيريدون ثنائي الببتیدIndex. décimale : 540 Chimie et sciences connexes Résumé : In the first chapter, we developed a novel catalytic synthesis of 3,4-
dihydropyrimidinones via Biginelli reaction in the presence of a bronsted ionic liquid [H-val]
HSO4 as the reaction medium. Then, we performed the synthesis of thiazolo[3,2-
a]pyrimidin-3(5H)-ones via Hantzsch thiazoles synthesis using bromide ethylacetoacetate as
an alkylatig agent in refluxed acetone, this novel method allowed to prepare these fused
heterocyclic compounds in good yields. Lability of hydrogens in previous derivatives allowed
to prepare new 2-benzilidénethiazolo[3,2-a]pyrimidin-3(5H)-ones via two methods: divergent
and convergent from DHPMs as starting materials.
In addition in the second chapter, we were interested in the development of novel
synthesis of 2-cyanopyridones via Hantzsch-like reaction using ammonium nitrate instead of the usually used ammonium acetate. Then we carried out several consecutive reactions on
these heterocyclic compounds to achieve the desired products: oxadiazolopyridines.
In the third chapter, we have prepared some dipeptide N-cyanopyridines from
cyanopyridines by carrying out some consecutive reactions.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/TEB7138.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10464 Nouvelles voies de synthèse des hétérocycles et des dipeptides à tête prosthétique [texte imprimé] / Imane Tebabel, Auteur ; Taoues Boumoud, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2017 . - 206 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Dihydropyrimidinones DHPMs liquide ionique thiazolopyrimidinones oxadiazolopyrimidines dipepetide Biginelli et pseudo Hantzsch nitrate d'ammonium ionic liquid Biginelli and Hantzsch-like مشتقات الدي هيدروبيريميدينون DHPM السائل الأيوني من ثیازولو[2,3-a] بیریمیدین3- (H25-
بنزیلدینثیازولو[2,3-a]بیریمیدین الأ كسادزول 3-سيانوبيريدون ثنائي الببتیدIndex. décimale : 540 Chimie et sciences connexes Résumé : In the first chapter, we developed a novel catalytic synthesis of 3,4-
dihydropyrimidinones via Biginelli reaction in the presence of a bronsted ionic liquid [H-val]
HSO4 as the reaction medium. Then, we performed the synthesis of thiazolo[3,2-
a]pyrimidin-3(5H)-ones via Hantzsch thiazoles synthesis using bromide ethylacetoacetate as
an alkylatig agent in refluxed acetone, this novel method allowed to prepare these fused
heterocyclic compounds in good yields. Lability of hydrogens in previous derivatives allowed
to prepare new 2-benzilidénethiazolo[3,2-a]pyrimidin-3(5H)-ones via two methods: divergent
and convergent from DHPMs as starting materials.
In addition in the second chapter, we were interested in the development of novel
synthesis of 2-cyanopyridones via Hantzsch-like reaction using ammonium nitrate instead of the usually used ammonium acetate. Then we carried out several consecutive reactions on
these heterocyclic compounds to achieve the desired products: oxadiazolopyridines.
In the third chapter, we have prepared some dipeptide N-cyanopyridines from
cyanopyridines by carrying out some consecutive reactions.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/TEB7138.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10464 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TEB/7138 TEB/7138 Thèse Bibliothèque principale Thèses Disponible
