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Titre : Etude des effets pharmaco toxicologieques de plantes médicinales d'Algérie : Activité cicatrisante et innocuité de l'huile végétale de Pistacia lentiscus L. Type de document : texte imprimé Auteurs : Zouhir Djerrou, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : Constantine : Université Mentouri Constantine Année de publication : 2011 Importance : 135 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Tags : Pistacia lentiscus L. vegetable oil dermal burns wound healing irritation toxicity hepato-renal function huile végétale brûlures cutanées cicatrisation toxicité, fonction hépatorénale ??? ????? ???? ????? ?????? ????? ??????? ??????? ??????? Index. décimale : 636 Sciences Vétérinaires Résumé :
Pistacia lentiscus L. is an evergreen shrub of 1 to 3 m high belonging to the family of Anacardiaceae. It is a traditional remedy which has been used by many ancient civilizations like Greeks and Egyptians. All parts of these plants have medicinal properties. However, the medicinal properties of vegetable oil extracted from fruits are particularly well known in North Africa, especially in the eastern region of Algeria to Tunisia. The inhabitants of these regions have used this oil for sore throat remedy, for treating skin burns and respiratory allergies.
The present work is a scientifc contribution to study some pharmacological and toxicological effects of this oil which kept our attention by its reputation in traditional medicine. The test of the Eye irritation / corrosion, showed that this oil is only slightly irritating to rabbit eye.
Similarly, the test of acute toxicity: Dermal irritation/corrosion allowed us to classify PLFO as slightly irritating to the skin, either intact or abraded. Repeated dermal toxicity test showed that this oil produced no edema, but a slight erythema was observed after the second week of application. This phenomenon is growing and regressing alternately until the end of the experiment, the latter does not exceed the rating of 2. One third of rabbits presented a phenomenon of local sensitization with skin thickening, which could reach 100% of the skin of the untreated regions. This phenomenon had been perfectly reversible and the skin has found its normal texture in a few days. As for the rectal route, the present oil was well tolerated. No anatomical or functional disturbance was observed in pathological examinations and histology. The biochemical parameters showed a significant decrease in AST and ALT
enzymes finding a positive impact of this oil on liver function. A significant increase in blood glucose, but still within the range of physiological norms, was recorded in suggesting a possible anti glycogenesis effect.
PLFO has also shown promising healing properties, this latter by reducing the inflammatory phase, stimulation of wound contraction and reducing the epithelization period.
The study concludes that Pistacia lentiscus fatty oil is effective for healing burns. It is tolerable in the short term, but may cause skin sensitization after prolonged use.Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/DJE6135.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9532 Etude des effets pharmaco toxicologieques de plantes médicinales d'Algérie : Activité cicatrisante et innocuité de l'huile végétale de Pistacia lentiscus L. [texte imprimé] / Zouhir Djerrou, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - Constantine : Université Mentouri Constantine, 2011 . - 135 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Tags : Pistacia lentiscus L. vegetable oil dermal burns wound healing irritation toxicity hepato-renal function huile végétale brûlures cutanées cicatrisation toxicité, fonction hépatorénale ??? ????? ???? ????? ?????? ????? ??????? ??????? ??????? Index. décimale : 636 Sciences Vétérinaires Résumé :
Pistacia lentiscus L. is an evergreen shrub of 1 to 3 m high belonging to the family of Anacardiaceae. It is a traditional remedy which has been used by many ancient civilizations like Greeks and Egyptians. All parts of these plants have medicinal properties. However, the medicinal properties of vegetable oil extracted from fruits are particularly well known in North Africa, especially in the eastern region of Algeria to Tunisia. The inhabitants of these regions have used this oil for sore throat remedy, for treating skin burns and respiratory allergies.
The present work is a scientifc contribution to study some pharmacological and toxicological effects of this oil which kept our attention by its reputation in traditional medicine. The test of the Eye irritation / corrosion, showed that this oil is only slightly irritating to rabbit eye.
Similarly, the test of acute toxicity: Dermal irritation/corrosion allowed us to classify PLFO as slightly irritating to the skin, either intact or abraded. Repeated dermal toxicity test showed that this oil produced no edema, but a slight erythema was observed after the second week of application. This phenomenon is growing and regressing alternately until the end of the experiment, the latter does not exceed the rating of 2. One third of rabbits presented a phenomenon of local sensitization with skin thickening, which could reach 100% of the skin of the untreated regions. This phenomenon had been perfectly reversible and the skin has found its normal texture in a few days. As for the rectal route, the present oil was well tolerated. No anatomical or functional disturbance was observed in pathological examinations and histology. The biochemical parameters showed a significant decrease in AST and ALT
enzymes finding a positive impact of this oil on liver function. A significant increase in blood glucose, but still within the range of physiological norms, was recorded in suggesting a possible anti glycogenesis effect.
PLFO has also shown promising healing properties, this latter by reducing the inflammatory phase, stimulation of wound contraction and reducing the epithelization period.
The study concludes that Pistacia lentiscus fatty oil is effective for healing burns. It is tolerable in the short term, but may cause skin sensitization after prolonged use.Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/DJE6135.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9532 Exemplaires
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Titre : Phénomène inflammatoire chez le poulet de chair et la poule pondeuse : Essai thérapeutique Type de document : texte imprimé Auteurs : Bouchra Souheila Benlaksira, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 197 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Tags : Opuntia ficus indica Lapins, Brûlures Cicatrisation Poulet de chair Alimentation Paramètres zootechniques Profil biochimique et histologique Rabbits Burns Wound healing Chicken Food Zootechnical parameters Biochemical and histological profiles ???????? ????? ?????? ??????? ?????? ???? ?????? ???? ????? ???? ???????? ????????? ????????????? ????????? Index. décimale : 636 Sciences Vétérinaires Résumé : Prickly pear or Barbary fig (Opuntia ficus indica L Mill) is a plant growing in arid and semiarid regions, besides its oil which is among the richest oils in the world, this plant is characterized by its many therapeutic virtues.
In our first study, the burn healing effect of the aqueous extract of the cladodes (pads) of Opuncia ficus indica as well as the effect of the mixture of this extract with the fruit seeds powder, was evaluated on experimental burns in a rabbit model. The results obtained confirm the positive effect of the plant in the healing process, by significantly reducing the wound area through accelerating wound contraction, which lead to a shorter healing time compared to the control and the cicatryl® groups. Histological study showed that wounds treated with presented a thinning of the epidermis and a neovascularization of the granulation tissue with a good distribution of sudoriparous and sebaceous structures and a formation of a surface keratin layer favourable for good tissue
regeneration. Several wounds treated with the cladodes’ aqueous extract presented a normal restitution
of the initial aspect of the skin (ad integrum).
Our second study conducted on broiler chicken aimed to test the effect of the incorporation of the seeds of the fruit of Opuntia ficus indica in the birds’ feed as well as the addition of the aqueous extract of the cladodes in their drinking water. Products were aded using different concentrations 1%, 2% and 5%. The results obtained in terms of weight, feed conversion ratio and carcass yield are better in the experimental group (5%). Blood biochemical parameters were not modified by this incorporation, and remained in the physiological norms.
An increase in liver and kidneys weights of the birds supplemented with 5% fruit seed was observed but has no impact on the functioning of these two organs. In fact, the majority of the histological sections showed a conserved overall morphology of the liver and the kidneys, which testifies the safety of our plant.
Thus, at the end of this study, we can say that Opuntia ficus indica (Fruit seeds and cladodes aqueous extract), respectively incorporated in the feed and drinking water at 5%, improves both live and carcass performances of broilers, compared to 1% and 2% complementation. However, other studies should be undertaken in order to provide a better exploitation of this plant.
Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/BEN7273.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10888 Phénomène inflammatoire chez le poulet de chair et la poule pondeuse : Essai thérapeutique [texte imprimé] / Bouchra Souheila Benlaksira, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2018 . - 197 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Tags : Opuntia ficus indica Lapins, Brûlures Cicatrisation Poulet de chair Alimentation Paramètres zootechniques Profil biochimique et histologique Rabbits Burns Wound healing Chicken Food Zootechnical parameters Biochemical and histological profiles ???????? ????? ?????? ??????? ?????? ???? ?????? ???? ????? ???? ???????? ????????? ????????????? ????????? Index. décimale : 636 Sciences Vétérinaires Résumé : Prickly pear or Barbary fig (Opuntia ficus indica L Mill) is a plant growing in arid and semiarid regions, besides its oil which is among the richest oils in the world, this plant is characterized by its many therapeutic virtues.
In our first study, the burn healing effect of the aqueous extract of the cladodes (pads) of Opuncia ficus indica as well as the effect of the mixture of this extract with the fruit seeds powder, was evaluated on experimental burns in a rabbit model. The results obtained confirm the positive effect of the plant in the healing process, by significantly reducing the wound area through accelerating wound contraction, which lead to a shorter healing time compared to the control and the cicatryl® groups. Histological study showed that wounds treated with presented a thinning of the epidermis and a neovascularization of the granulation tissue with a good distribution of sudoriparous and sebaceous structures and a formation of a surface keratin layer favourable for good tissue
regeneration. Several wounds treated with the cladodes’ aqueous extract presented a normal restitution
of the initial aspect of the skin (ad integrum).
Our second study conducted on broiler chicken aimed to test the effect of the incorporation of the seeds of the fruit of Opuntia ficus indica in the birds’ feed as well as the addition of the aqueous extract of the cladodes in their drinking water. Products were aded using different concentrations 1%, 2% and 5%. The results obtained in terms of weight, feed conversion ratio and carcass yield are better in the experimental group (5%). Blood biochemical parameters were not modified by this incorporation, and remained in the physiological norms.
An increase in liver and kidneys weights of the birds supplemented with 5% fruit seed was observed but has no impact on the functioning of these two organs. In fact, the majority of the histological sections showed a conserved overall morphology of the liver and the kidneys, which testifies the safety of our plant.
Thus, at the end of this study, we can say that Opuntia ficus indica (Fruit seeds and cladodes aqueous extract), respectively incorporated in the feed and drinking water at 5%, improves both live and carcass performances of broilers, compared to 1% and 2% complementation. However, other studies should be undertaken in order to provide a better exploitation of this plant.
Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/BEN7273.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10888 Exemplaires
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