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Auteur Youcef Hamdi Pacha |
Documents disponibles écrits par cet auteur (12)
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Titre : Effets biologiques de la petite centaurée Erythraea centaurium (L.) Pers. Type de document : texte imprimé Auteurs : Louiza Benhamza, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2008 Importance : 184 p. Format : 30 cm. Note générale : 01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD Langues : Français (fre) Catégories : Français - Anglais
Sciences VétérinairesTags : Toxicité Phytothérapie DiabbLte type 2 Photothérapie Petite centaurée Erythraea centaurium L. Rats Hyperglycémie Diabetes type2 phytotherapy Erythreae centaurium L. rats hyperglycemia toxicity مرض السكري نوع 2 المعالجة بالنباتات القنطريون فئران جرذان زيادة سكر الدم Index. décimale : 636 Sciences Vétérinaires Résumé : Diabetis type 2 is a frequent and severe disease. Its complications constitute a public health problem.
It needs drugs, food diet and medical monitoring.
Now day, in therapeutically field, in addition to conventional treatment (insulin and oral hypoglycaeming
agents) use medicinal plants as complementary treatment as well as treatment in low glycemia.
Therefore phytotherapy constitutes a good alternative or at least as a complement to classical drugs.
In popular medicine, a lot of plants -among them, the Centaurium erythreae - are used in diabetic
treatment.
The first part of this work treats literature review on diabetes, phytotherapy and Centaurium erythreae L.
The second part consists of an experimental work that contains:
- Inquiries on the use of medicinal plants in our regions (east, south-east and Algiers region); 39 species
belonging to 24 families are noted.
- A chemical experiment of the flowering stems of the plant Erythreae centaurium L. has been done;
several products were identified( flavonoids, alkaloids, steroids and tannins...).
- An experimental work on normoglycemic rats and rats submitted to hyperglycemia by oral means by
overcharge of glucose, by gavage of aqueous and butanolic extract of the Common Centaury. After
kinetic study of glycaemia between tB0 Band tB180 Bminutes by glycometery and spectrophotometer shows an
important decrease of blood glucose rates.
The hypoglycemic action of aqueous and butanolic extract was compared to that obtained
rats with hypoglycemic agent (Glibenclamide (DCI) Daonil ® (ND)
This shows the existence hypoglycemic action of Common Centaury.
- The monitoring of rats, during fifteen days after hyperglycemia shows secondary effects of aquous and
butanolic extracts of Common Centaury on liver and kidney rats’.Diplôme : Doctorat En ligne : ../theses/veterinaire/BEN5276.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=1871 Effets biologiques de la petite centaurée Erythraea centaurium (L.) Pers. [texte imprimé] / Louiza Benhamza, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2008 . - 184 p. ; 30 cm.
01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD
Langues : Français (fre)
Catégories : Français - Anglais
Sciences VétérinairesTags : Toxicité Phytothérapie DiabbLte type 2 Photothérapie Petite centaurée Erythraea centaurium L. Rats Hyperglycémie Diabetes type2 phytotherapy Erythreae centaurium L. rats hyperglycemia toxicity مرض السكري نوع 2 المعالجة بالنباتات القنطريون فئران جرذان زيادة سكر الدم Index. décimale : 636 Sciences Vétérinaires Résumé : Diabetis type 2 is a frequent and severe disease. Its complications constitute a public health problem.
It needs drugs, food diet and medical monitoring.
Now day, in therapeutically field, in addition to conventional treatment (insulin and oral hypoglycaeming
agents) use medicinal plants as complementary treatment as well as treatment in low glycemia.
Therefore phytotherapy constitutes a good alternative or at least as a complement to classical drugs.
In popular medicine, a lot of plants -among them, the Centaurium erythreae - are used in diabetic
treatment.
The first part of this work treats literature review on diabetes, phytotherapy and Centaurium erythreae L.
The second part consists of an experimental work that contains:
- Inquiries on the use of medicinal plants in our regions (east, south-east and Algiers region); 39 species
belonging to 24 families are noted.
- A chemical experiment of the flowering stems of the plant Erythreae centaurium L. has been done;
several products were identified( flavonoids, alkaloids, steroids and tannins...).
- An experimental work on normoglycemic rats and rats submitted to hyperglycemia by oral means by
overcharge of glucose, by gavage of aqueous and butanolic extract of the Common Centaury. After
kinetic study of glycaemia between tB0 Band tB180 Bminutes by glycometery and spectrophotometer shows an
important decrease of blood glucose rates.
The hypoglycemic action of aqueous and butanolic extract was compared to that obtained
rats with hypoglycemic agent (Glibenclamide (DCI) Daonil ® (ND)
This shows the existence hypoglycemic action of Common Centaury.
- The monitoring of rats, during fifteen days after hyperglycemia shows secondary effects of aquous and
butanolic extracts of Common Centaury on liver and kidney rats’.Diplôme : Doctorat En ligne : ../theses/veterinaire/BEN5276.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=1871 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEN/5276 BEN/5276 Thèse Bibliothèque principale Thèses Disponible Effets de la corticotherapie sur quelques parametres biochimiques et hematologiques du cheval et du chien / Djamel Eddine Kraouchi
Titre : Effets de la corticotherapie sur quelques parametres biochimiques et hematologiques du cheval et du chien Type de document : texte imprimé Auteurs : Djamel Eddine Kraouchi, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : Constantine : Université Mentouri Constantine Année de publication : 2011 Importance : 81 f. Format : 31 cm. Note générale : Doctorat en sciences
2 copies imprimées disponiblesLangues : Français (fre) Catégories : Français - Anglais
Sciences VétérinairesTags : Paramètres biochimiques rapport PN/L Dexaméthasone Affections pulmonaires obstructives chroniques Cheval Chien Sidérémie Méthylprednisolone Index. décimale : 636 Sciences Vétérinaires Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/KRA6173.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=6112 Effets de la corticotherapie sur quelques parametres biochimiques et hematologiques du cheval et du chien [texte imprimé] / Djamel Eddine Kraouchi, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - Constantine : Université Mentouri Constantine, 2011 . - 81 f. ; 31 cm.
Doctorat en sciences
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
Sciences VétérinairesTags : Paramètres biochimiques rapport PN/L Dexaméthasone Affections pulmonaires obstructives chroniques Cheval Chien Sidérémie Méthylprednisolone Index. décimale : 636 Sciences Vétérinaires Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/KRA6173.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=6112 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KRA/6173 KRA/6173 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude botanique et phytochimique : Approche biologique et pharmacologique d'opuntia ficus indica Type de document : texte imprimé Auteurs : Sihem Halmi, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : Constantine : Université Mentouri Constantine Année de publication : 2015 Importance : 115 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Biotechnologies végétales "Opuntia ficus indica cytogénétique HPLC Activité antiradicalaire Pouvoir antimicrobien Toxicité Pharmacologie Potentiel allélopathique Cytogenetic Radical scavenging activity Antimicrobial power Toxicity Pharmacology Allelopathic potential الوراثة الخلوٌة النشاط المضاد للبكتٌرٌا السمٌة الدوائٌة كابح
الانباتIndex. décimale : 570 Sciences de la vie. Biologie Résumé : The prickly pear (Opuntia ficus indica), it’s cactus of the genus Opuntia, which contains a many medicinal properties.
The organization of the genome study of this species by using the conventional cytogenetics methods: acetic carmine and silver nitrate (AgNO3) staining, indicates that this species is octoploid 2n = 88 with a base number x = 11. The karyotype reveals the presence of three types of chromosome. The coloration with a silver nitrate indicates a number of nucleoli varies from 1 to 4 with a majority of one nucleolus per cell found that there is an active site.
Our work has focuses also on Opuntia ficus indica cladods extracts study. The analysis of these extracts by HPLC and colorimetric tests shows the presence of some chemical groups (total polyphenols) capable of expressing the desired activity. Theirs antiradical activities are evaluated through chemical tests such as hydrogen peroxide, hydroxyl radical, DPPH, FRAP scavenging tests and the phosphomolybdate method. The result shows a high reducing activity of certain extracts.
The antibacterial activity of this extracts is evaluated by the solid medium diffusion and the MIC is determined by the liquid medium dilution methods. The results show that the EAc has the highest power on the Staphylococcus aureus strain.
The results of toxicology tests performed in vitro and in vivo, on erythrocytes blood isolates, larvae, rats and rabbits indicate that this plant has very low toxicity.
The various pharmacological tests perform in vivo of the aqueous extract of Opuntia ficus indica shows that it has important properties: hypoglycemic, very significant analgesic activity; using pain models induced by chemical and thermal stimuli, better wound contraction during the inflammatory response and the proliferative phase, and also it causes a significant improvement in hepatic antioxidant status in rats there were liver toxicity induced by CCL4.
Allelopathic compounds detected in the cladods of prickly pear are phenolic compounds that have an inhibitory effect on the germination and growth of the target plant.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HAL6732.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9891 Etude botanique et phytochimique : Approche biologique et pharmacologique d'opuntia ficus indica [texte imprimé] / Sihem Halmi, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - Constantine : Université Mentouri Constantine, 2015 . - 115 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Biotechnologies végétales "Opuntia ficus indica cytogénétique HPLC Activité antiradicalaire Pouvoir antimicrobien Toxicité Pharmacologie Potentiel allélopathique Cytogenetic Radical scavenging activity Antimicrobial power Toxicity Pharmacology Allelopathic potential الوراثة الخلوٌة النشاط المضاد للبكتٌرٌا السمٌة الدوائٌة كابح
الانباتIndex. décimale : 570 Sciences de la vie. Biologie Résumé : The prickly pear (Opuntia ficus indica), it’s cactus of the genus Opuntia, which contains a many medicinal properties.
The organization of the genome study of this species by using the conventional cytogenetics methods: acetic carmine and silver nitrate (AgNO3) staining, indicates that this species is octoploid 2n = 88 with a base number x = 11. The karyotype reveals the presence of three types of chromosome. The coloration with a silver nitrate indicates a number of nucleoli varies from 1 to 4 with a majority of one nucleolus per cell found that there is an active site.
Our work has focuses also on Opuntia ficus indica cladods extracts study. The analysis of these extracts by HPLC and colorimetric tests shows the presence of some chemical groups (total polyphenols) capable of expressing the desired activity. Theirs antiradical activities are evaluated through chemical tests such as hydrogen peroxide, hydroxyl radical, DPPH, FRAP scavenging tests and the phosphomolybdate method. The result shows a high reducing activity of certain extracts.
The antibacterial activity of this extracts is evaluated by the solid medium diffusion and the MIC is determined by the liquid medium dilution methods. The results show that the EAc has the highest power on the Staphylococcus aureus strain.
The results of toxicology tests performed in vitro and in vivo, on erythrocytes blood isolates, larvae, rats and rabbits indicate that this plant has very low toxicity.
The various pharmacological tests perform in vivo of the aqueous extract of Opuntia ficus indica shows that it has important properties: hypoglycemic, very significant analgesic activity; using pain models induced by chemical and thermal stimuli, better wound contraction during the inflammatory response and the proliferative phase, and also it causes a significant improvement in hepatic antioxidant status in rats there were liver toxicity induced by CCL4.
Allelopathic compounds detected in the cladods of prickly pear are phenolic compounds that have an inhibitory effect on the germination and growth of the target plant.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HAL6732.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9891 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité HAL/6732 HAL/6732 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude des effets pharmaco toxicologieques de plantes médicinales d'Algérie : Activité cicatrisante et innocuité de l'huile végétale de Pistacia lentiscus L. Type de document : texte imprimé Auteurs : Zouhir Djerrou, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : Constantine : Université Mentouri Constantine Année de publication : 2011 Importance : 135 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Catégories : Français - Anglais
Sciences VétérinairesTags : Pistacia lentiscus L. vegetable oil dermal burns wound healing irritation toxicity hepato-renal function huile végétale brûlures cutanées cicatrisation toxicité, fonction hépatorénale زیت نباتي حروق الجلد التئام الجرح التهيّج السميّة الوظيفة الكبدیة الوظيفة الكلویة Index. décimale : 636 Sciences Vétérinaires Résumé :
Pistacia lentiscus L. is an evergreen shrub of 1 to 3 m high belonging to the family of Anacardiaceae. It is a traditional remedy which has been used by many ancient civilizations like Greeks and Egyptians. All parts of these plants have medicinal properties. However, the medicinal properties of vegetable oil extracted from fruits are particularly well known in North Africa, especially in the eastern region of Algeria to Tunisia. The inhabitants of these regions have used this oil for sore throat remedy, for treating skin burns and respiratory allergies.
The present work is a scientifc contribution to study some pharmacological and toxicological effects of this oil which kept our attention by its reputation in traditional medicine. The test of the Eye irritation / corrosion, showed that this oil is only slightly irritating to rabbit eye.
Similarly, the test of acute toxicity: Dermal irritation/corrosion allowed us to classify PLFO as slightly irritating to the skin, either intact or abraded. Repeated dermal toxicity test showed that this oil produced no edema, but a slight erythema was observed after the second week of application. This phenomenon is growing and regressing alternately until the end of the experiment, the latter does not exceed the rating of 2. One third of rabbits presented a phenomenon of local sensitization with skin thickening, which could reach 100% of the skin of the untreated regions. This phenomenon had been perfectly reversible and the skin has found its normal texture in a few days. As for the rectal route, the present oil was well tolerated. No anatomical or functional disturbance was observed in pathological examinations and histology. The biochemical parameters showed a significant decrease in AST and ALT
enzymes finding a positive impact of this oil on liver function. A significant increase in blood glucose, but still within the range of physiological norms, was recorded in suggesting a possible anti glycogenesis effect.
PLFO has also shown promising healing properties, this latter by reducing the inflammatory phase, stimulation of wound contraction and reducing the epithelization period.
The study concludes that Pistacia lentiscus fatty oil is effective for healing burns. It is tolerable in the short term, but may cause skin sensitization after prolonged use.Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/DJE6135.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9532 Etude des effets pharmaco toxicologieques de plantes médicinales d'Algérie : Activité cicatrisante et innocuité de l'huile végétale de Pistacia lentiscus L. [texte imprimé] / Zouhir Djerrou, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - Constantine : Université Mentouri Constantine, 2011 . - 135 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
Sciences VétérinairesTags : Pistacia lentiscus L. vegetable oil dermal burns wound healing irritation toxicity hepato-renal function huile végétale brûlures cutanées cicatrisation toxicité, fonction hépatorénale زیت نباتي حروق الجلد التئام الجرح التهيّج السميّة الوظيفة الكبدیة الوظيفة الكلویة Index. décimale : 636 Sciences Vétérinaires Résumé :
Pistacia lentiscus L. is an evergreen shrub of 1 to 3 m high belonging to the family of Anacardiaceae. It is a traditional remedy which has been used by many ancient civilizations like Greeks and Egyptians. All parts of these plants have medicinal properties. However, the medicinal properties of vegetable oil extracted from fruits are particularly well known in North Africa, especially in the eastern region of Algeria to Tunisia. The inhabitants of these regions have used this oil for sore throat remedy, for treating skin burns and respiratory allergies.
The present work is a scientifc contribution to study some pharmacological and toxicological effects of this oil which kept our attention by its reputation in traditional medicine. The test of the Eye irritation / corrosion, showed that this oil is only slightly irritating to rabbit eye.
Similarly, the test of acute toxicity: Dermal irritation/corrosion allowed us to classify PLFO as slightly irritating to the skin, either intact or abraded. Repeated dermal toxicity test showed that this oil produced no edema, but a slight erythema was observed after the second week of application. This phenomenon is growing and regressing alternately until the end of the experiment, the latter does not exceed the rating of 2. One third of rabbits presented a phenomenon of local sensitization with skin thickening, which could reach 100% of the skin of the untreated regions. This phenomenon had been perfectly reversible and the skin has found its normal texture in a few days. As for the rectal route, the present oil was well tolerated. No anatomical or functional disturbance was observed in pathological examinations and histology. The biochemical parameters showed a significant decrease in AST and ALT
enzymes finding a positive impact of this oil on liver function. A significant increase in blood glucose, but still within the range of physiological norms, was recorded in suggesting a possible anti glycogenesis effect.
PLFO has also shown promising healing properties, this latter by reducing the inflammatory phase, stimulation of wound contraction and reducing the epithelization period.
The study concludes that Pistacia lentiscus fatty oil is effective for healing burns. It is tolerable in the short term, but may cause skin sensitization after prolonged use.Diplôme : Doctorat en sciences En ligne : ../theses/veterinaire/DJE6135.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9532 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité DJE/6135 DJE/6135 Thèse Bibliothèque principale Thèses Disponible Documents numériques
texte intégraleAdobe Acrobat PDF
Titre : Etude in vitro de l'effet antibactérien et antifongique de : Inula viscosa -Lawsonia inermis- Asphodelus microcarpus - Aloe vera- Juniperus oxycedrus Type de document : texte imprimé Auteurs : Tounsi Lynda Bensegueni, Auteur ; Youcef Hamdi Pacha, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2005 Importance : 99 f. Format : 30 cm. Note générale : 01 Disponible à la salle de recherche 02 Disponibles au magazin de la bibliothèque centrale Langues : Français (fre) Catégories : Français - Anglais
Sciences VétérinairesTags : Aloe vera Inula viscosa Lawsonia inermis Asphodelus microcarpus Juniperus oxycedrus Index. décimale : 636 Sciences Vétérinaires Diplôme : Magistère En ligne : ../theses/veterinaire/BEN4392.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=1884 Etude in vitro de l'effet antibactérien et antifongique de : Inula viscosa -Lawsonia inermis- Asphodelus microcarpus - Aloe vera- Juniperus oxycedrus [texte imprimé] / Tounsi Lynda Bensegueni, Auteur ; Youcef Hamdi Pacha, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2005 . - 99 f. ; 30 cm.
01 Disponible à la salle de recherche 02 Disponibles au magazin de la bibliothèque centrale
Langues : Français (fre)
Catégories : Français - Anglais
Sciences VétérinairesTags : Aloe vera Inula viscosa Lawsonia inermis Asphodelus microcarpus Juniperus oxycedrus Index. décimale : 636 Sciences Vétérinaires Diplôme : Magistère En ligne : ../theses/veterinaire/BEN4392.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=1884 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEN/4392 BEN/4392 Thèse Bibliothèque principale Thèses Disponible
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