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Auteur Nour-eddine Beghidja |
Documents disponibles écrits par cet auteur (3)
Affiner la recherche Interroger des sources externesEtude chimique et biologique des espèces Calligonum azel et Calligonum comosum (Polygonaceae) et une espèce du genre Thymus (Lamiaceae). / Soumia Belaabed Khalfaoui
Titre : Etude chimique et biologique des espèces Calligonum azel et Calligonum comosum (Polygonaceae) et une espèce du genre Thymus (Lamiaceae). Type de document : texte imprimé Auteurs : Soumia Belaabed Khalfaoui, Auteur ; Nour-eddine Beghidja, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 250 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Calligonum azel Calligonum comosum Thymus ciliatus Polygonaceae Lamiaceae RMN 1D et 2D CLHP HRESIMS activités biologiques huile essentielle NMR 1D and 2D HPLC Biological activities essential oil مطيافية الرنين المغناطيسي1D و2D كروماتوغرافيا HPLC مطيافية الكتلة النضاطات البيولوجية الزيوت الأساسية Index. décimale : 540 Chimie et sciences connexes Résumé : The phytochemical and biological study concerns the aerial parts of two endemic Saharian species belonging to the polygonaceae family: Calligonum azel and Calligonum comosum and a third one belonging to the Lamiaceae family.
The object of our work focused on the valorization of the Algerian flora. For this, firstly; we carried out a phytochemical study on Calligonum azel and Calligonum comosum which concerned mainly the biologically active compounds then we tested the antioxidant, antibacterial, antifungal and anti-inflammatory properties of all the organic extracts and some isolated compounds. Secondly; we studied the chemical composition and biological activities of Thymus ciliatus essential oil.
The study of aerial parts of C. azel and C. comosum, in order to know the active compounds responsible for their biological activity, leading to purification, chromatographic identification (CC, TLC and HPLC), and characterization using the different spectroscopic methods (1D and 2D NMR, MS and UV) of twenty one pure compounds (21) in which eighteen (18) compounds were identified.
The investigation of the biological activities of the extracts of Calligonum azel and Calligonum comosum showed that the best antioxidant activity was exhibited by the Chloroform and ethyl acetate extracts of C. azel and the Chloroform extract of C. comosum. The chloroform extracts of both species showed the best antibacterial activity. Chloroform extract from C. comosum has better antifungal activity against Candida albicans ATCC 2019 and Candida parapsilosis ATCC 22019.
From the isolated compounds, three have an antioxidant and anti-inflammatory activity. These compounds were: protocatachuic ethyl ester acid, -diamino (4-hydroxy benzene) butanoic acid and tamgernanetin.
The qualitative and quantitative analysis of essential oil of T. ciliatus allows the identification of 25 compounds representing 87.18 % of the total essential oil mainly. The GC and GC-MS analysis showed that this essential oils was mainly rich of thymol (54.26%), carvacrol methyl ether (1,373 %), o-cymene (5.72 %) carvacrol (1.373%)-cymen-7-ol (17.58 %), however it was the first time that -cymen-7-ol (17.58 %) was found as main component in the essential oils of T. ciliatus.
The evaluation of the antibacterial activity was assessed by disc diffusion method against bacterial strains. The essential oil exhibited a good antibacterial activity against Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 43300 and Staphylocossus aureus.
All of our works confirms the medicinal properties of the Saharian species, and contributes to their scientific descriptions.Diplôme : Doctorat En ligne : ../theses/chimie/BEL7311.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10926 Etude chimique et biologique des espèces Calligonum azel et Calligonum comosum (Polygonaceae) et une espèce du genre Thymus (Lamiaceae). [texte imprimé] / Soumia Belaabed Khalfaoui, Auteur ; Nour-eddine Beghidja, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 250 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Calligonum azel Calligonum comosum Thymus ciliatus Polygonaceae Lamiaceae RMN 1D et 2D CLHP HRESIMS activités biologiques huile essentielle NMR 1D and 2D HPLC Biological activities essential oil مطيافية الرنين المغناطيسي1D و2D كروماتوغرافيا HPLC مطيافية الكتلة النضاطات البيولوجية الزيوت الأساسية Index. décimale : 540 Chimie et sciences connexes Résumé : The phytochemical and biological study concerns the aerial parts of two endemic Saharian species belonging to the polygonaceae family: Calligonum azel and Calligonum comosum and a third one belonging to the Lamiaceae family.
The object of our work focused on the valorization of the Algerian flora. For this, firstly; we carried out a phytochemical study on Calligonum azel and Calligonum comosum which concerned mainly the biologically active compounds then we tested the antioxidant, antibacterial, antifungal and anti-inflammatory properties of all the organic extracts and some isolated compounds. Secondly; we studied the chemical composition and biological activities of Thymus ciliatus essential oil.
The study of aerial parts of C. azel and C. comosum, in order to know the active compounds responsible for their biological activity, leading to purification, chromatographic identification (CC, TLC and HPLC), and characterization using the different spectroscopic methods (1D and 2D NMR, MS and UV) of twenty one pure compounds (21) in which eighteen (18) compounds were identified.
The investigation of the biological activities of the extracts of Calligonum azel and Calligonum comosum showed that the best antioxidant activity was exhibited by the Chloroform and ethyl acetate extracts of C. azel and the Chloroform extract of C. comosum. The chloroform extracts of both species showed the best antibacterial activity. Chloroform extract from C. comosum has better antifungal activity against Candida albicans ATCC 2019 and Candida parapsilosis ATCC 22019.
From the isolated compounds, three have an antioxidant and anti-inflammatory activity. These compounds were: protocatachuic ethyl ester acid, -diamino (4-hydroxy benzene) butanoic acid and tamgernanetin.
The qualitative and quantitative analysis of essential oil of T. ciliatus allows the identification of 25 compounds representing 87.18 % of the total essential oil mainly. The GC and GC-MS analysis showed that this essential oils was mainly rich of thymol (54.26%), carvacrol methyl ether (1,373 %), o-cymene (5.72 %) carvacrol (1.373%)-cymen-7-ol (17.58 %), however it was the first time that -cymen-7-ol (17.58 %) was found as main component in the essential oils of T. ciliatus.
The evaluation of the antibacterial activity was assessed by disc diffusion method against bacterial strains. The essential oil exhibited a good antibacterial activity against Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 43300 and Staphylocossus aureus.
All of our works confirms the medicinal properties of the Saharian species, and contributes to their scientific descriptions.Diplôme : Doctorat En ligne : ../theses/chimie/BEL7311.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10926 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEL/7311 BEL/7311 Thèse Bibliothèque principale Thèses Disponible
Titre : Investigation phytochimique de l’extrait n-butanol du Globularia alypum L : (Globulariaceae) Type de document : texte imprimé Auteurs : Naima Rahmouni, Auteur ; Nour-eddine Beghidja, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 105 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : iridoids Globulraia alypum L Globulraiceae phénylethanoid الفنيلايثانويدات؛الاريدويدات؛
iridoids Globularia alypum L GlobulriaceaeIndex. décimale : 540 Chimie et sciences connexes Résumé : This work is devoted to the phytochemical study of the Algerian plant named Globularia
alypum L, belonging to the family Globulariaceae. This latter is widely distributed in the plant
kingdom is known for its richness in secondary metabolites such as flavonoids phenylethanoids
and iridoids.
This chemical study has led to the isolation by chromatographic methods and
characterization by spectroscopic methods focused mainly on the RMN1D and 2D, 3 secondary
metabolites:
1) D- Mannitol
2) Syringin
3) Globularin
The molecular structures of the isolated compounds were elucidated primarily through the
use of techniques 1D and 2D NMR (
1
H,
13
C J-modulated HH COSY, HSQC HMBC and
NOESY), by mass spectrometry.
The results of this work will be presented as follows:
The first chapter is devoted to a reminder bibliographic including a description of the
botanical family and genus
The second chapter is devoted to a study of polyphenols and iridoids.
The phytochemical studies of the species will be presented in the third chapter.
The fourth chapter, results and discussion.Diplôme : Magistère En ligne : ../theses/chimie/RAH6395.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9411 Investigation phytochimique de l’extrait n-butanol du Globularia alypum L : (Globulariaceae) [texte imprimé] / Naima Rahmouni, Auteur ; Nour-eddine Beghidja, Directeur de thèse . - constantine [Algérie] : Université Constantine 1, 2013 . - 105 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : iridoids Globulraia alypum L Globulraiceae phénylethanoid الفنيلايثانويدات؛الاريدويدات؛
iridoids Globularia alypum L GlobulriaceaeIndex. décimale : 540 Chimie et sciences connexes Résumé : This work is devoted to the phytochemical study of the Algerian plant named Globularia
alypum L, belonging to the family Globulariaceae. This latter is widely distributed in the plant
kingdom is known for its richness in secondary metabolites such as flavonoids phenylethanoids
and iridoids.
This chemical study has led to the isolation by chromatographic methods and
characterization by spectroscopic methods focused mainly on the RMN1D and 2D, 3 secondary
metabolites:
1) D- Mannitol
2) Syringin
3) Globularin
The molecular structures of the isolated compounds were elucidated primarily through the
use of techniques 1D and 2D NMR (
1
H,
13
C J-modulated HH COSY, HSQC HMBC and
NOESY), by mass spectrometry.
The results of this work will be presented as follows:
The first chapter is devoted to a reminder bibliographic including a description of the
botanical family and genus
The second chapter is devoted to a study of polyphenols and iridoids.
The phytochemical studies of the species will be presented in the third chapter.
The fourth chapter, results and discussion.Diplôme : Magistère En ligne : ../theses/chimie/RAH6395.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9411 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité RAH/6395 RAH/6395 Thèse Bibliothèque principale Thèses Disponible Documents numériques
texte intégraleAdobe Acrobat PDF
Titre : Phytochemical and biological studies of Scabiosa stellata.L (Caprifoliaceae) & Sedum carealeum. Vahl (Crassulaceae). Type de document : texte imprimé Auteurs : Naima Rahmouni, Auteur ; Nour-eddine Beghidja, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 224 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Anglais (eng) Catégories : Français - Anglais
ChimieTags : acides gras GC-MS LC-MS profil phénolique Scabiosa et Sedum fatty acids Scabiosa and Sedum الأحماض الدھنیة المحتوى الفینولي Index. décimale : 540 Chimie et sciences connexes Résumé : his present work concerns the phytochemical and biological study of two Algerian plants Scabiosa stelatta.L and Sedum carealeum vahl. Chromatographic separations and purifications of these plants led to the isolation and identification of 18( S. stellata) and 3 compounds(S. carealeum). data.GC/MS analyses of hexane extract S. stellata allowed the identification of 43 metabolites belonging to several important families, fatty acids and their derivatives (87%) are the major ones, wherever 19 metabolites were identified and alkenes ( 60%) is the major family followed by 30% of fatty acids in hexane extract of second plant. S. stellata showed a good activity antioxidant with: DPPH, ABTS and Reducing Power tests. Compared with the other tested extracts, the n-butanol extract showed the highest activity. Using UHPLC-DAD-ESI/MSn, the knowledge of the S. stellata phenolic profile was successfully extended, for the first time establishing its content in important secondary metabolites, such as chlorogenic acids and flavonoids. Chlorogenic acids and flavonoids comprised more than 80% of the compounds found, which explains the recently reported antioxidant activity of this plant extract.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/RAH7341.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10991 Phytochemical and biological studies of Scabiosa stellata.L (Caprifoliaceae) & Sedum carealeum. Vahl (Crassulaceae). [texte imprimé] / Naima Rahmouni, Auteur ; Nour-eddine Beghidja, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 224 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Anglais (eng)
Catégories : Français - Anglais
ChimieTags : acides gras GC-MS LC-MS profil phénolique Scabiosa et Sedum fatty acids Scabiosa and Sedum الأحماض الدھنیة المحتوى الفینولي Index. décimale : 540 Chimie et sciences connexes Résumé : his present work concerns the phytochemical and biological study of two Algerian plants Scabiosa stelatta.L and Sedum carealeum vahl. Chromatographic separations and purifications of these plants led to the isolation and identification of 18( S. stellata) and 3 compounds(S. carealeum). data.GC/MS analyses of hexane extract S. stellata allowed the identification of 43 metabolites belonging to several important families, fatty acids and their derivatives (87%) are the major ones, wherever 19 metabolites were identified and alkenes ( 60%) is the major family followed by 30% of fatty acids in hexane extract of second plant. S. stellata showed a good activity antioxidant with: DPPH, ABTS and Reducing Power tests. Compared with the other tested extracts, the n-butanol extract showed the highest activity. Using UHPLC-DAD-ESI/MSn, the knowledge of the S. stellata phenolic profile was successfully extended, for the first time establishing its content in important secondary metabolites, such as chlorogenic acids and flavonoids. Chlorogenic acids and flavonoids comprised more than 80% of the compounds found, which explains the recently reported antioxidant activity of this plant extract.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/RAH7341.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10991 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité RAH/7341 RAH/7341 Thèse Bibliothèque principale Thèses Disponible
