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Partager le résultat de cette recherche Interroger des sources externesEtudes phytochimique et pharmacologique d’une plante saharienne et d’espèces de la région des Aurès. / Hamza Fadel
Titre : Etudes phytochimique et pharmacologique d’une plante saharienne et d’espèces de la région des Aurès. Type de document : texte imprimé Auteurs : Hamza Fadel, Auteur ; Samir Benayache, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 255 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Pulicaria inuloides Cistus albidus les Aurès fractionnement bioguidé activité biologique flavonoïdes huiles essentielles ICP-AES et ICP-MS Aures bioguided fractionation biological activity flavonoids essential oils Pulicaria inuloides??????? ???????? ?????????? ????? ?????? ???????? ?????? ??????? ??????? ?????? ???????? ????? ) (ICP-AES??????? ?????? ?????? )(. ICP-M" Index. décimale : 540 Chimie et sciences connexes Résumé : Our goal in this work was to search the secondary metabolites of flavonoids type from two species from Asteraceae and Cistaceae families in order to search new natural compounds of biological interest. Thirteen (13) extracts from different species including twelve (12) from the Aures regions were subjected to a phytochemical screening. On the basis of these preliminary results, the phytochemical investigation of the aerial parts two species, Pulicaria inuloides and Cistus albidus from the Bechar and the Aures regions respectively was carried out. This approach allowed the isolation of twelve natural compounds, among which eleven flavonoids, one phenolic compound as well as two acetyl derivatives of one of the isolated compounds were characterized using spectroscopic methods such as UV-Visible, IR and NMR.
The biological activities in vitro (antioxidant and antibacterial activity) as well as the total phenolic and flavonoids compounds of the various extracts were discussed. We also reported the evaluation of the in vitro antiprotozoal activity of the two species Pulicaria inuloides and Cistus albidus against Leishmania amazonensis, Trypanosoma cruzi and Acanthamoeba castellanii str. Neff. The bioguided fractionation of the CHCl3 extract from the aerial part of P. inuloides leads to the isolation and characterization of quercetagetin-3,5,7,3'-tetramethylether as the active ingredient. Two acetylated derivatives were prepared from this natural compound and these three compounds were evaluated for their activities against the promastigote form of L. amazonensis.
All these compounds exhibited moderate leishmanicidal activity with IC50 values ranging from 0.234 to 0.484 mM and low toxicity to macrophage cells (CC50 ranging from 0.365 to 0.664 mM). This study reported the antiprotozoal evaluation of Pulicaria inuloides for the first time and the results show that this species can be considered as a source of anti-leishmanicidal agents. The bioguided fractionation of the active extract of CHCl3 from C. albidus against T. cruzi led to the isolation of two fractions F6,4 and F6,5 which showed also a potent activity up to 100 μg/ml. The bioguided fractionation of the active extract of AcOEt from the aerial part of C. albidus against A. castellanii led to the isolation of a fraction F14A which showed a significant activity up to 100 μg / ml. Fractions F6,4 ; F6,5 and F14A consists of product mixtures, which have not been separated.
We have also described the chemical compositions of the essential oils of Pulicaria inuloides and Cistus albidus. The major compounds of the species C. albidus are manool and 15,16-dinorlabd-8(20)- en-13-one whose skeleton of type labdane is a specific marker in this genus, these compounds are not described in samples from other regions and in particular in the Mediterranean regions (Spain and France) that appeared in the literature. The major compounds of the species Pulicaria inuloides are: δ- cadinene, α-muurolene, γ-cadinene, α-epi-cadinol and α-cadinol are not present in the other samples of Pulicaria inuloides from other areas published in the literature.
In this study, the mineral content (inorganic elements) of 21 isolated extracts of various aromatic species of the Sahara (P. inuloides) and the Aures region (Euphorbia helioscopia L., Peganum harmala L., Daphne gnidium L., Calendula algeriensis L., Bunium incrassatum L., Echinops ritro L. Marrubium deserti de Noè., Juniperus oxycedrus L., Juniperus phoenicea L., Marrubium vulgare L., Cedrus atlantica (Endl.) Manetti and Thymus algeriensis L.) were also determined by inductively coupled plasma atomic emission spectroscopy (ICP-AES) and inductively coupled plasma mass spectroscopy (ICP-MS) . The results obtained showed higher concentrations of Ca, K, Mg, Na and S
(mg/kg) in the different plant extracts.
Diplôme : Doctorat En ligne : ../theses/chimie/FAD7287.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10902 Etudes phytochimique et pharmacologique d’une plante saharienne et d’espèces de la région des Aurès. [texte imprimé] / Hamza Fadel, Auteur ; Samir Benayache, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2018 . - 255 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Pulicaria inuloides Cistus albidus les Aurès fractionnement bioguidé activité biologique flavonoïdes huiles essentielles ICP-AES et ICP-MS Aures bioguided fractionation biological activity flavonoids essential oils Pulicaria inuloides??????? ???????? ?????????? ????? ?????? ???????? ?????? ??????? ??????? ?????? ???????? ????? ) (ICP-AES??????? ?????? ?????? )(. ICP-M" Index. décimale : 540 Chimie et sciences connexes Résumé : Our goal in this work was to search the secondary metabolites of flavonoids type from two species from Asteraceae and Cistaceae families in order to search new natural compounds of biological interest. Thirteen (13) extracts from different species including twelve (12) from the Aures regions were subjected to a phytochemical screening. On the basis of these preliminary results, the phytochemical investigation of the aerial parts two species, Pulicaria inuloides and Cistus albidus from the Bechar and the Aures regions respectively was carried out. This approach allowed the isolation of twelve natural compounds, among which eleven flavonoids, one phenolic compound as well as two acetyl derivatives of one of the isolated compounds were characterized using spectroscopic methods such as UV-Visible, IR and NMR.
The biological activities in vitro (antioxidant and antibacterial activity) as well as the total phenolic and flavonoids compounds of the various extracts were discussed. We also reported the evaluation of the in vitro antiprotozoal activity of the two species Pulicaria inuloides and Cistus albidus against Leishmania amazonensis, Trypanosoma cruzi and Acanthamoeba castellanii str. Neff. The bioguided fractionation of the CHCl3 extract from the aerial part of P. inuloides leads to the isolation and characterization of quercetagetin-3,5,7,3'-tetramethylether as the active ingredient. Two acetylated derivatives were prepared from this natural compound and these three compounds were evaluated for their activities against the promastigote form of L. amazonensis.
All these compounds exhibited moderate leishmanicidal activity with IC50 values ranging from 0.234 to 0.484 mM and low toxicity to macrophage cells (CC50 ranging from 0.365 to 0.664 mM). This study reported the antiprotozoal evaluation of Pulicaria inuloides for the first time and the results show that this species can be considered as a source of anti-leishmanicidal agents. The bioguided fractionation of the active extract of CHCl3 from C. albidus against T. cruzi led to the isolation of two fractions F6,4 and F6,5 which showed also a potent activity up to 100 μg/ml. The bioguided fractionation of the active extract of AcOEt from the aerial part of C. albidus against A. castellanii led to the isolation of a fraction F14A which showed a significant activity up to 100 μg / ml. Fractions F6,4 ; F6,5 and F14A consists of product mixtures, which have not been separated.
We have also described the chemical compositions of the essential oils of Pulicaria inuloides and Cistus albidus. The major compounds of the species C. albidus are manool and 15,16-dinorlabd-8(20)- en-13-one whose skeleton of type labdane is a specific marker in this genus, these compounds are not described in samples from other regions and in particular in the Mediterranean regions (Spain and France) that appeared in the literature. The major compounds of the species Pulicaria inuloides are: δ- cadinene, α-muurolene, γ-cadinene, α-epi-cadinol and α-cadinol are not present in the other samples of Pulicaria inuloides from other areas published in the literature.
In this study, the mineral content (inorganic elements) of 21 isolated extracts of various aromatic species of the Sahara (P. inuloides) and the Aures region (Euphorbia helioscopia L., Peganum harmala L., Daphne gnidium L., Calendula algeriensis L., Bunium incrassatum L., Echinops ritro L. Marrubium deserti de Noè., Juniperus oxycedrus L., Juniperus phoenicea L., Marrubium vulgare L., Cedrus atlantica (Endl.) Manetti and Thymus algeriensis L.) were also determined by inductively coupled plasma atomic emission spectroscopy (ICP-AES) and inductively coupled plasma mass spectroscopy (ICP-MS) . The results obtained showed higher concentrations of Ca, K, Mg, Na and S
(mg/kg) in the different plant extracts.
Diplôme : Doctorat En ligne : ../theses/chimie/FAD7287.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10902 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité FAD/7287 FAD/7287 Thèse Bibliothèque principale Thèses Disponible
Titre : Impact de plantes riches en métabolites secondaires sur la méthanogénèse ruminale et les activités fermentaires du microbiome ruminal chez des ovins Type de document : texte imprimé Auteurs : Moufida Rira, Auteur ; H. Bousseboua, Directeur de thèse ; Michel Doreau, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 201 f. Format : 30 cm. Note générale : 2 copies imprimes disponibles Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Méthane tanins condensés huiles essentielles fermentation microbiote ruminal moutons Methane condensed tannins essential oils rumen microbes sheep????? ??????? ???? ????? ???????? ????? ?????? Index. décimale : 570 Sciences de la vie. Biologie Résumé : Strategies of methane reduction will have to take into account the other environmental
impacts and the social-economic stakes. Therefore, the main encouraging way envisaged to
reduce enteric methane is the use of additives containing plants secondary metabolites.
The objective of this thesis work was to test at first the in vitro potential of essential
oil extracts and condensed tannins-rich plants to reduce methane production. Secondly, an in
vivo study was conducted for a validation of results obtained in vitro and for a better
knowledge of ruminal methanogenesis and fermentative phenomena.
Our work allows concluding that essential oil and condensed tannins have the potential
to decrease in vitro methane production. Essential oils of Mentha pulegium and Juniperus
phoenicea negatively affect in vitro ruminal fermentation. Condensed tannins reduce in vivo
methane production without notable unwanted effects on ruminal fermentation and on
digestibility. The effect of condensed tannins is rather linked to the dose and not to the nature
of the plant. This work also highlighted the absence of relation between concentration and
diversity of methanogens and methanogenesis. Reduction of methane is due to the inhibition
of the activity of methanogens rather than to the decrease of their concentration. The
presentation of tannins rich plants under granular shape had also accelerated the transit.
Results from the in vivo study suggests that dietary condensed tannins from Leucaena
leucocephala, Manihot esculenta, and to a lesser extent from Gliricidia sepium in pellet form
could be used to mitigate methane production with no marked detrimental effects on other
fermentative parameters.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/RIR6839.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10114 Impact de plantes riches en métabolites secondaires sur la méthanogénèse ruminale et les activités fermentaires du microbiome ruminal chez des ovins [texte imprimé] / Moufida Rira, Auteur ; H. Bousseboua, Directeur de thèse ; Michel Doreau, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2015 . - 201 f. ; 30 cm.
2 copies imprimes disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Méthane tanins condensés huiles essentielles fermentation microbiote ruminal moutons Methane condensed tannins essential oils rumen microbes sheep????? ??????? ???? ????? ???????? ????? ?????? Index. décimale : 570 Sciences de la vie. Biologie Résumé : Strategies of methane reduction will have to take into account the other environmental
impacts and the social-economic stakes. Therefore, the main encouraging way envisaged to
reduce enteric methane is the use of additives containing plants secondary metabolites.
The objective of this thesis work was to test at first the in vitro potential of essential
oil extracts and condensed tannins-rich plants to reduce methane production. Secondly, an in
vivo study was conducted for a validation of results obtained in vitro and for a better
knowledge of ruminal methanogenesis and fermentative phenomena.
Our work allows concluding that essential oil and condensed tannins have the potential
to decrease in vitro methane production. Essential oils of Mentha pulegium and Juniperus
phoenicea negatively affect in vitro ruminal fermentation. Condensed tannins reduce in vivo
methane production without notable unwanted effects on ruminal fermentation and on
digestibility. The effect of condensed tannins is rather linked to the dose and not to the nature
of the plant. This work also highlighted the absence of relation between concentration and
diversity of methanogens and methanogenesis. Reduction of methane is due to the inhibition
of the activity of methanogens rather than to the decrease of their concentration. The
presentation of tannins rich plants under granular shape had also accelerated the transit.
Results from the in vivo study suggests that dietary condensed tannins from Leucaena
leucocephala, Manihot esculenta, and to a lesser extent from Gliricidia sepium in pellet form
could be used to mitigate methane production with no marked detrimental effects on other
fermentative parameters.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/RIR6839.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10114 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité RIR/6839 RIR/6839 Thèse Bibliothèque principale Thèses Disponible
Titre : استخلاص وتنقية المركبات الفعالة بيولوجيا من بعض الأنواع النباتية : : Ormenis africana Chrysanthemum fuscatum , Chrysanthemum macrocarpum et Chrysanthemum reboudianumمع دراسة مقارنة لنشاطيتها ضد ميكروبية Type de document : texte imprimé Auteurs : كمال درويش, Auteur ; صالح غواطي, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 214 ورقة. Format : 30 سم. Note générale : 2 نسخ موجودة في المكتبة المركزية Langues : Arabe (ara) Catégories : Arabe
5 البيولوجياTags : ???????????? ???????? ??????? ??????? . Chrysanthemum sp????????????? ?????? ???????? ????????
?? ???????? ???????? ?? ??????
Asteraceae Chrysanthemum sp. Flavonoides Essential oils Antimicrobial acivity Antioxydant acivity Asteraceae, Chrysanthemum sp. Flavonoïdes Huilles essentielles Activité antimicrobienne Activité antioxydanteIndex. décimale : 570 بيولوجيا Résumé : The phytochemical screening of species: Ormenis africana, Chrysanthemum macrocarpum,
C.mreboudianum and C. fuscatum shows the presence of essential oils, flavonoids, sterols or terpenes,saponins and carotenoids.
The GC/MS analysis of the essential oils of species: Oa, Cƒ and Cr showed that these oils contain major compounds with oxygenic functions (aldehydes, ketones, esters and acids) and that for theathreeaplants.
This study also allowed the isolate, the purify and the identify of three compounds from the flowers of Oa (B-sitosterol, Luteolin-7-O-glucoside and Quercetin-3-O-glucoside), the molecular structures of purified compounds were elucidated by UV spectroscopy techniques and NMR (1H, 13C).
Spectrometric quantitative determinations of total polyphenols by Folin-Ciocalteu reagent and flavonoids those prepared by the aluminum chloride AlCl3 revealed rich extracts (AcOEt and BuOH) by flavonoids and phenols contribution extracts (Hexane and CHCl3) of different species tested.
The antiradical potential of essential oils (Oa, Cƒ and Cr) and extracts (Hexane, CHCl3, EtOAc and BuOH) Oa and chrysanthemum species tested was determined by the method of DPPH and the results show that essential oil of Oa is most active by supplying essential oils (Cƒ and Cr). The extract butanol and ethyl acetate of the two species (Oa and Cm) in addition to the chloroform extract of the species Cƒ, demonstrated a remarkable antioxidant activity.
The antimicrobial potency testing, CMI and CMD has been made on a range of (bacteria and fungi) to give an idea of the scope of our antimicrobial activity (essential oils and flavonoid extracts), the EO of Oa seems to enjoy a remarkable inhibitory activity against Gram (+) tested and Candida albicans compared with the EO of Cƒ and EO of Cr appears less active. The results also show a sensitivity of Staphylococcus aureus and Pseudomonas aeruginosa resistant to the essential oils and various extracts tested.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/ADER4102.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10138 استخلاص وتنقية المركبات الفعالة بيولوجيا من بعض الأنواع النباتية : : Ormenis africana Chrysanthemum fuscatum , Chrysanthemum macrocarpum et Chrysanthemum reboudianumمع دراسة مقارنة لنشاطيتها ضد ميكروبية [texte imprimé] / كمال درويش, Auteur ; صالح غواطي, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2015 . - 214 ورقة. ; 30 سم.
2 نسخ موجودة في المكتبة المركزية
Langues : Arabe (ara)
Catégories : Arabe
5 البيولوجياTags : ???????????? ???????? ??????? ??????? . Chrysanthemum sp????????????? ?????? ???????? ????????
?? ???????? ???????? ?? ??????
Asteraceae Chrysanthemum sp. Flavonoides Essential oils Antimicrobial acivity Antioxydant acivity Asteraceae, Chrysanthemum sp. Flavonoïdes Huilles essentielles Activité antimicrobienne Activité antioxydanteIndex. décimale : 570 بيولوجيا Résumé : The phytochemical screening of species: Ormenis africana, Chrysanthemum macrocarpum,
C.mreboudianum and C. fuscatum shows the presence of essential oils, flavonoids, sterols or terpenes,saponins and carotenoids.
The GC/MS analysis of the essential oils of species: Oa, Cƒ and Cr showed that these oils contain major compounds with oxygenic functions (aldehydes, ketones, esters and acids) and that for theathreeaplants.
This study also allowed the isolate, the purify and the identify of three compounds from the flowers of Oa (B-sitosterol, Luteolin-7-O-glucoside and Quercetin-3-O-glucoside), the molecular structures of purified compounds were elucidated by UV spectroscopy techniques and NMR (1H, 13C).
Spectrometric quantitative determinations of total polyphenols by Folin-Ciocalteu reagent and flavonoids those prepared by the aluminum chloride AlCl3 revealed rich extracts (AcOEt and BuOH) by flavonoids and phenols contribution extracts (Hexane and CHCl3) of different species tested.
The antiradical potential of essential oils (Oa, Cƒ and Cr) and extracts (Hexane, CHCl3, EtOAc and BuOH) Oa and chrysanthemum species tested was determined by the method of DPPH and the results show that essential oil of Oa is most active by supplying essential oils (Cƒ and Cr). The extract butanol and ethyl acetate of the two species (Oa and Cm) in addition to the chloroform extract of the species Cƒ, demonstrated a remarkable antioxidant activity.
The antimicrobial potency testing, CMI and CMD has been made on a range of (bacteria and fungi) to give an idea of the scope of our antimicrobial activity (essential oils and flavonoid extracts), the EO of Oa seems to enjoy a remarkable inhibitory activity against Gram (+) tested and Candida albicans compared with the EO of Cƒ and EO of Cr appears less active. The results also show a sensitivity of Staphylococcus aureus and Pseudomonas aeruginosa resistant to the essential oils and various extracts tested.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/ADER4102.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10138 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité درو/4102 درو/4102 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude phytochimique et biologique de l'espèce Thymus numidicus Poiret Type de document : texte imprimé Auteurs : Feryal Benayache, Auteur ; Samir Benayache, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 141 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Thymus numidicus flavonoïdes activité antioxydante huiles essentielles terpènes GC/GC.MS flavonoids antioxidant activity essential oils terpenes ???????????? ?????? ??????? ????????? ??????? ??????? Index. décimale : 540 Chimie et sciences connexes Résumé : The thyme used since the antiquity in traditional medicine, is recognized by their therapeutic virtues.
In this context, the present work concerns phytochemical and biological studies of an endemic species Thymus numidicus (Poiret).
The phytochimical study led to the establishement six structures which were: Cirsilinéol, Cirsimaritin, Apigenin, Luteolin, Apigenin-7-O-glucuronide, Luteolin -7-O-glucuronide Antiradical potential of the n-BuOH extract was determined by the DPPH method, the order of IC50 is 35,08 μg/ ml.
The analysis by GC and GC-MS of the essential oil of T. numidicus, obtained by water steam practice led to the identification of 48 compounds belonging essentially to the class of the monoterpenes. From which the most important is thymol (54,18%) and p-cymen (15,38%).Diplôme : Magistère En ligne : ../theses/chimie/BEN6346.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6316 Etude phytochimique et biologique de l'espèce Thymus numidicus Poiret [texte imprimé] / Feryal Benayache, Auteur ; Samir Benayache, Directeur de thèse . - constantine (Route ain el bey, Algérie) : Université Constantine 1, 2013 . - 141 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Thymus numidicus flavonoïdes activité antioxydante huiles essentielles terpènes GC/GC.MS flavonoids antioxidant activity essential oils terpenes ???????????? ?????? ??????? ????????? ??????? ??????? Index. décimale : 540 Chimie et sciences connexes Résumé : The thyme used since the antiquity in traditional medicine, is recognized by their therapeutic virtues.
In this context, the present work concerns phytochemical and biological studies of an endemic species Thymus numidicus (Poiret).
The phytochimical study led to the establishement six structures which were: Cirsilinéol, Cirsimaritin, Apigenin, Luteolin, Apigenin-7-O-glucuronide, Luteolin -7-O-glucuronide Antiradical potential of the n-BuOH extract was determined by the DPPH method, the order of IC50 is 35,08 μg/ ml.
The analysis by GC and GC-MS of the essential oil of T. numidicus, obtained by water steam practice led to the identification of 48 compounds belonging essentially to the class of the monoterpenes. From which the most important is thymol (54,18%) and p-cymen (15,38%).Diplôme : Magistère En ligne : ../theses/chimie/BEN6346.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6316 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEN/6346 BEN/6346 Thèse Bibliothèque principale Thèses Disponible
Titre : استخلاص، فصل وتحديد بنى نواتج الأيض الثانوي الفلافونيدي وتركيب الزيوت الأساسية لنباتات من الجنس ((Fabaceae) Genista Type de document : texte imprimé Auteurs : كوثر شباح, Auteur ; رتيبة مكيو, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 193 ورقة. Format : 30 سم. Note générale : 2نسخ موجودة مكتبة المركزية
Langues : Arabe (ara) Catégories : Arabe
القانونTags : Fabaceae Genista cephalantha Spach. Genista ulicina Spach. Genista quadriflora Munby Genista cinerea ssp. ramosissima phytochemical
screening antioxidant activity essential oils Genista cephalantha Spach Genista ulicina Spach Genista
quadriflora Munby composés flavonoiques activité
antioxydante huiles essentielles Genista quadriflora ?Genista ulicina Spach. ?Genista cephalantha Spachby? ?Genista cinerea ssp. ramosissima??????? ????????? ????? ??????? ????? ???? ????????? ??????????? ????? ???????Index. décimale : 340 القانون Résumé : The principal aim of the present work consisted to identify the secondary metabolites of
four species Genista cephalantha Spach.,Genista ulicina Spach., Genista quadriflora
Munby and Genista cinerea ssp. ramosissima belonging to the Fabaceae family.
This study began with a preliminary phytochemical screening by using the classic
methods, the analysis by HPLC-UV followed by a quantification of phenolic and
flavonoid content by colorimetric methods and finally the evaluation of antioxidant
activity of both species (Genista cephalantha Spach. and Genista ulicina Spach.) by
measuring their ability to scavenge a stable DPPH free radical and by β-
Carotene/linoleic acid bleaching assay. The obtained results showed a wealth of both
species in flavonoids and isoflavonoids and a good antioxidant activity. These results
gave rise to two international publications.
The extracts of these two plants were subjected to separation and purification
methods, based on chromatographic techniques.Ten compounds were isolated
from the aerial parts of Genista cephalantha and three compounds from Genista
ulicina. All isolated compounds were identified by spectroscopic analysis,
especially 1D and 2D NMR spectroscopy (1H-NMR, 13C-NMR, DEPT 90,
DEPT135, COSY, HMQC, HMBC), UV spectrophotometry aswelle as Mass
Spectrometry (ESI(-)).
The analyses of essential oil of G. quadriflora et G. cinerea ssp. ramosissima by
GC and GC/MS led the identification of forty four (44) compounds from G.
quadrifloraMunby, with7,10,13-Hexadecatrienal (13.38%) as main compound,
and fifty seven (57) compounds from the essential oil of G.
cinereassp. ramosissima with phthalate (20.15%) as main compound.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/ACHE4239.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10445 استخلاص، فصل وتحديد بنى نواتج الأيض الثانوي الفلافونيدي وتركيب الزيوت الأساسية لنباتات من الجنس ((Fabaceae) Genista [texte imprimé] / كوثر شباح, Auteur ; رتيبة مكيو, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2017 . - 193 ورقة. ; 30 سم.
2نسخ موجودة مكتبة المركزية
Langues : Arabe (ara)
Catégories : Arabe
القانونTags : Fabaceae Genista cephalantha Spach. Genista ulicina Spach. Genista quadriflora Munby Genista cinerea ssp. ramosissima phytochemical
screening antioxidant activity essential oils Genista cephalantha Spach Genista ulicina Spach Genista
quadriflora Munby composés flavonoiques activité
antioxydante huiles essentielles Genista quadriflora ?Genista ulicina Spach. ?Genista cephalantha Spachby? ?Genista cinerea ssp. ramosissima??????? ????????? ????? ??????? ????? ???? ????????? ??????????? ????? ???????Index. décimale : 340 القانون Résumé : The principal aim of the present work consisted to identify the secondary metabolites of
four species Genista cephalantha Spach.,Genista ulicina Spach., Genista quadriflora
Munby and Genista cinerea ssp. ramosissima belonging to the Fabaceae family.
This study began with a preliminary phytochemical screening by using the classic
methods, the analysis by HPLC-UV followed by a quantification of phenolic and
flavonoid content by colorimetric methods and finally the evaluation of antioxidant
activity of both species (Genista cephalantha Spach. and Genista ulicina Spach.) by
measuring their ability to scavenge a stable DPPH free radical and by β-
Carotene/linoleic acid bleaching assay. The obtained results showed a wealth of both
species in flavonoids and isoflavonoids and a good antioxidant activity. These results
gave rise to two international publications.
The extracts of these two plants were subjected to separation and purification
methods, based on chromatographic techniques.Ten compounds were isolated
from the aerial parts of Genista cephalantha and three compounds from Genista
ulicina. All isolated compounds were identified by spectroscopic analysis,
especially 1D and 2D NMR spectroscopy (1H-NMR, 13C-NMR, DEPT 90,
DEPT135, COSY, HMQC, HMBC), UV spectrophotometry aswelle as Mass
Spectrometry (ESI(-)).
The analyses of essential oil of G. quadriflora et G. cinerea ssp. ramosissima by
GC and GC/MS led the identification of forty four (44) compounds from G.
quadrifloraMunby, with7,10,13-Hexadecatrienal (13.38%) as main compound,
and fifty seven (57) compounds from the essential oil of G.
cinereassp. ramosissima with phthalate (20.15%) as main compound.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/ACHE4239.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10445 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité شبا/4239 شبا/4239 Thèse Bibliothèque principale Thèses Disponible
