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Auteur Ramdane Seghiri |
Documents disponibles écrits par cet auteur (7)
Affiner la recherche Interroger des sources externesElimination des substances humiques extraites de l'eau de la retenue de Hammam-Grouz par coagulation-floculation avec le chèorure ferrique et le sulfate d'aluminium / Ramdane Seghiri
Titre : Elimination des substances humiques extraites de l'eau de la retenue de Hammam-Grouz par coagulation-floculation avec le chèorure ferrique et le sulfate d'aluminium Type de document : texte imprimé Auteurs : Ramdane Seghiri ; Univ. de Constantine, Éditeur scientifique ; B. Legube, Directeur de thèse Année de publication : 1996 Importance : 91 f. Note générale : 03 Disponibles au magasin de la bibliothèque centrale Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Eau Chèore ferrique Sulfate d'aluminium Index. décimale : 540 Chimie et sciences connexes Permalink : index.php?lvl=notice_display&id=4227 Elimination des substances humiques extraites de l'eau de la retenue de Hammam-Grouz par coagulation-floculation avec le chèorure ferrique et le sulfate d'aluminium [texte imprimé] / Ramdane Seghiri ; Univ. de Constantine, Éditeur scientifique ; B. Legube, Directeur de thèse . - 1996 . - 91 f.
03 Disponibles au magasin de la bibliothèque centrale
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Eau Chèore ferrique Sulfate d'aluminium Index. décimale : 540 Chimie et sciences connexes Permalink : index.php?lvl=notice_display&id=4227 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité SEG/2905 SEG/2905 Thèse Bibliothèque principale Thèses Disponible 
Titre : Investigation phytochimique et biologique des espèces Centaurea involucrata, Senecio massaicus, Thymus algeriensis et Marrubium vulgare. Type de document : texte imprimé Auteurs : Sara Kebbi ép Chebli, Auteur ; Ramdane Seghiri, Directeur de thèse Mention d'édition : 06-juin-21 Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2021 Importance : 255 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie:Chimie Pharmaceutique Chimie Pharmaceutique: Analyses physicochimiques, contrôle qualité et synthèse de substances bioactives Centaurea involucrata Desf. huiles essentielles docking moléculaire Covid-19 GC/MS antiproliférative anticholinestérase essential oil molecular docking anticancer anticholinesterase الزيوت الأساسية الالتحام الجزيئي كوفيد 19مضادات التكاثر مضادات الكولينستيراز Index. décimale : 540 Chimie et sciences connexes Résumé :
On the one hand, this study is focused on a phytochemical and biological investigation of Centaurea involucrata Desf., an Algerian species that has never been the subject of phytochemical investigation. On the other hand, the chemical composition of the essential oils of Thymus algeriensis , Marrubium vulgare, and Senecio massaicus aerial parts, as well as the assessment of the biological activities of the last specie's essential oil. The petroleum ether extract of C. involucrata was studied using GC-MS, and 13 compounds were identified, the majority of which have a wide range of activities. The HPLC/DAD analysis of phenolic acids and flavonoids of chloroform and n-butanol extracts showed the presence of seven phenolic acids and three flavonoids. While, the LC-MS/MS analysis of the ethyl acetate extract showed the presence of 26 phenolic compounds. The various chromatographics methods of separation used in our research allowed the insulation of 11 products from the ethyl acetate extract. The structures of these compounds were elucidated by combining the results of analyzes of UV spectra, 1D NMR (1H, 13C and DEPT) and 2D NMR (COZY, HSQC, HMBC and NOESY) and by comparison with data from the literature. The biological activity tests on the extracts, which included antioxidant, antimicrobial, and anticancer activity, showed that the species has notable antioxidant and anticancer activities. The chemical analysis of the essential oil of the aerial parts of T. algeriensis, M. vulgare and S. massaicus by GC-MS, showed that the major constituents are: germacrene D (29.6%), β-caryophyllene (11.0%) for T. algeriensis, β-bisabolene (36.3%) for M. vulgare and m-cymene (30.5%), n-hexadecanoic acid (14.8%), and docosane-11-decyl (10.43%) for S. massaicus. The essential oil of S. massaicus has on one hand moderate antioxidant activity, and the other hand has a higher power of inhibition against butyrylcholinesterase (BChE) compared to acetylcholinesterase (AChE). The molecular docking study shows that the compounds docosane-11-decyl and octaethyleneglycol monododecyl ether exhibited a strong interaction against enzymes linked to Alzheimer's disease and against the main protease Covid-19 and endoribonuclease Nsp15.
Note de contenu : Annexes. Diplôme : Doctorat En ligne : ../theses/chimie/KEB7762.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11595 Investigation phytochimique et biologique des espèces Centaurea involucrata, Senecio massaicus, Thymus algeriensis et Marrubium vulgare. [texte imprimé] / Sara Kebbi ép Chebli, Auteur ; Ramdane Seghiri, Directeur de thèse . - 06-juin-21 . - جامعة الإخوة منتوري قسنطينة, 2021 . - 255 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie:Chimie Pharmaceutique Chimie Pharmaceutique: Analyses physicochimiques, contrôle qualité et synthèse de substances bioactives Centaurea involucrata Desf. huiles essentielles docking moléculaire Covid-19 GC/MS antiproliférative anticholinestérase essential oil molecular docking anticancer anticholinesterase الزيوت الأساسية الالتحام الجزيئي كوفيد 19مضادات التكاثر مضادات الكولينستيراز Index. décimale : 540 Chimie et sciences connexes Résumé :
On the one hand, this study is focused on a phytochemical and biological investigation of Centaurea involucrata Desf., an Algerian species that has never been the subject of phytochemical investigation. On the other hand, the chemical composition of the essential oils of Thymus algeriensis , Marrubium vulgare, and Senecio massaicus aerial parts, as well as the assessment of the biological activities of the last specie's essential oil. The petroleum ether extract of C. involucrata was studied using GC-MS, and 13 compounds were identified, the majority of which have a wide range of activities. The HPLC/DAD analysis of phenolic acids and flavonoids of chloroform and n-butanol extracts showed the presence of seven phenolic acids and three flavonoids. While, the LC-MS/MS analysis of the ethyl acetate extract showed the presence of 26 phenolic compounds. The various chromatographics methods of separation used in our research allowed the insulation of 11 products from the ethyl acetate extract. The structures of these compounds were elucidated by combining the results of analyzes of UV spectra, 1D NMR (1H, 13C and DEPT) and 2D NMR (COZY, HSQC, HMBC and NOESY) and by comparison with data from the literature. The biological activity tests on the extracts, which included antioxidant, antimicrobial, and anticancer activity, showed that the species has notable antioxidant and anticancer activities. The chemical analysis of the essential oil of the aerial parts of T. algeriensis, M. vulgare and S. massaicus by GC-MS, showed that the major constituents are: germacrene D (29.6%), β-caryophyllene (11.0%) for T. algeriensis, β-bisabolene (36.3%) for M. vulgare and m-cymene (30.5%), n-hexadecanoic acid (14.8%), and docosane-11-decyl (10.43%) for S. massaicus. The essential oil of S. massaicus has on one hand moderate antioxidant activity, and the other hand has a higher power of inhibition against butyrylcholinesterase (BChE) compared to acetylcholinesterase (AChE). The molecular docking study shows that the compounds docosane-11-decyl and octaethyleneglycol monododecyl ether exhibited a strong interaction against enzymes linked to Alzheimer's disease and against the main protease Covid-19 and endoribonuclease Nsp15.
Note de contenu : Annexes. Diplôme : Doctorat En ligne : ../theses/chimie/KEB7762.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11595 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEB/7762 KEB/7762 Thèse Bibliothèque principale Thèses Disponible
Titre : Investigation phytochimique et pharmacologique de deux espèces du genre Linaria : (Scrophulariaceae) Type de document : texte imprimé Auteurs : Thamere Cheriet, Auteur ; Ramdane Seghiri, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 328 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Linaria tingitana Boiss. & Reut. Linaria reflexa Desf. étude phytochimique in
vivo in vitro antioxydante antidiabétique anti-inflammatoire antimicrobienne phytochemical study antioxidant anti-diabetic anti-inflammatory antimicrobial الدراسةالفيتوكيميائية في الجسم الحي في ا لمختبر المضاد للأكسدة المضادة لمرض السكر المضادةللالتهابات مضادةللميكروبات.Index. décimale : 540 Chimie et sciences connexes Résumé : A bibliographic research on the genus Linaria (Scrophulariaceae), a genus well distributed in Algeria, shows that it has not used for much studies, which encouraged us to undertake this phytochemical investigation of two species which the first is an endemic one for Algeria and Morocco with the absence of biological and phytochemical literature data, whereas the second one is an used plant in traditional medicine for the treatment of certain skin diseases. The
separation and purification of the extracts of L. tingitana with various chromatographic techniques, allowed the identification of ten products, and the identification of their structures using spectroscopic methods: four triterpenes (1 pentacyclic triterpene and 3 sterols), four iridoids (1 detected with LC-MS), two flavones and one sugar. The study of Linaria reflexa led the detection with LC-MS of six glycosylated flavonoids and the isolation and the identification of eight products in which 2 are detected by LC-MS:
four flavones (2 glycosylated and 2 aglycones), one iridoid, one lignan, one methyl ester and one sugar. The biological tests on antioxidant (in vivo and in vitro), anti-diabetic (in vivo), anti-inflammatory and antimicrobial (in vitro) activities, showed that both plants have remarkable anti-diabetic and anti-inflammatory activities
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/CHE6795.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10025 Investigation phytochimique et pharmacologique de deux espèces du genre Linaria : (Scrophulariaceae) [texte imprimé] / Thamere Cheriet, Auteur ; Ramdane Seghiri, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 328 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Linaria tingitana Boiss. & Reut. Linaria reflexa Desf. étude phytochimique in
vivo in vitro antioxydante antidiabétique anti-inflammatoire antimicrobienne phytochemical study antioxidant anti-diabetic anti-inflammatory antimicrobial الدراسةالفيتوكيميائية في الجسم الحي في ا لمختبر المضاد للأكسدة المضادة لمرض السكر المضادةللالتهابات مضادةللميكروبات.Index. décimale : 540 Chimie et sciences connexes Résumé : A bibliographic research on the genus Linaria (Scrophulariaceae), a genus well distributed in Algeria, shows that it has not used for much studies, which encouraged us to undertake this phytochemical investigation of two species which the first is an endemic one for Algeria and Morocco with the absence of biological and phytochemical literature data, whereas the second one is an used plant in traditional medicine for the treatment of certain skin diseases. The
separation and purification of the extracts of L. tingitana with various chromatographic techniques, allowed the identification of ten products, and the identification of their structures using spectroscopic methods: four triterpenes (1 pentacyclic triterpene and 3 sterols), four iridoids (1 detected with LC-MS), two flavones and one sugar. The study of Linaria reflexa led the detection with LC-MS of six glycosylated flavonoids and the isolation and the identification of eight products in which 2 are detected by LC-MS:
four flavones (2 glycosylated and 2 aglycones), one iridoid, one lignan, one methyl ester and one sugar. The biological tests on antioxidant (in vivo and in vitro), anti-diabetic (in vivo), anti-inflammatory and antimicrobial (in vitro) activities, showed that both plants have remarkable anti-diabetic and anti-inflammatory activities
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/CHE6795.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10025 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité CHE/6795 CHE/6795 Thèse Bibliothèque principale Thèses Disponible
Titre : Recherche et détermination structurale des métabolites secondaires de l’espèce Centaurea microcarpa (Asteraceae). Type de document : texte imprimé Auteurs : Samia Baatouche, Auteur ; Ramdane Seghiri, Directeur de thèse Mention d'édition : 08/07/2021 Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2021 Importance : 181 f. Format : 30 cm. Note générale : 1 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie organique: Phytochimie Astéracées Centaurea microcarpa Coss. & Dur. flavonoïdes sesquiterpènes lactones glycosides cyanogéniques et lignanes Asteraceae Centaurea microcarpa flavonoids sesquiterpene lactones cyanogenic glycoside lignanes العائلة المركبة Centaurea microcarpaالفلافونيدات السيسكويتربينات اللاكتونية السييانوجينيك جلوكوزيد الليجنانات Index. décimale : 540 Chimie et sciences connexes Résumé :
This work is devoted to the phytochemical study of Centaurea microcarpa Coss. and Dur. of the genus Centaurea (Asteraceae), endemic to Algeria and Tunisia. The phytochemical investigation of chloroform and ethyl acetate extracts obtained from the aerial parts of C. microcarpa, led to the isolation and identification of nine products.
The chloroform extract of this plant has permitted to isolate and identify four compounds which were: one cyanogenic glycoside, an eudesmanolide and tow steroids as a mixture each. While the ethyl acetate extract gave five compounds which were three flavonoids, one lignane and one cyanogenic. The structural elucidation of these compounds were established by modern spectroscopic methods including ultraviolet spectrophotometer, NMR spectroscopy (1H, 13C, DEPT, COSY, HSQC, HMBC and ROESY) and mass spectrometry HESI (+) and IEMS, and by comparison
with the literature data.
Note de contenu : Annexes. Diplôme : Doctorat en sciences En ligne : ../theses/chimie/BAA7824.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11656 Recherche et détermination structurale des métabolites secondaires de l’espèce Centaurea microcarpa (Asteraceae). [texte imprimé] / Samia Baatouche, Auteur ; Ramdane Seghiri, Directeur de thèse . - 08/07/2021 . - جامعة الإخوة منتوري قسنطينة, 2021 . - 181 f. ; 30 cm.
1 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie organique: Phytochimie Astéracées Centaurea microcarpa Coss. & Dur. flavonoïdes sesquiterpènes lactones glycosides cyanogéniques et lignanes Asteraceae Centaurea microcarpa flavonoids sesquiterpene lactones cyanogenic glycoside lignanes العائلة المركبة Centaurea microcarpaالفلافونيدات السيسكويتربينات اللاكتونية السييانوجينيك جلوكوزيد الليجنانات Index. décimale : 540 Chimie et sciences connexes Résumé :
This work is devoted to the phytochemical study of Centaurea microcarpa Coss. and Dur. of the genus Centaurea (Asteraceae), endemic to Algeria and Tunisia. The phytochemical investigation of chloroform and ethyl acetate extracts obtained from the aerial parts of C. microcarpa, led to the isolation and identification of nine products.
The chloroform extract of this plant has permitted to isolate and identify four compounds which were: one cyanogenic glycoside, an eudesmanolide and tow steroids as a mixture each. While the ethyl acetate extract gave five compounds which were three flavonoids, one lignane and one cyanogenic. The structural elucidation of these compounds were established by modern spectroscopic methods including ultraviolet spectrophotometer, NMR spectroscopy (1H, 13C, DEPT, COSY, HSQC, HMBC and ROESY) and mass spectrometry HESI (+) and IEMS, and by comparison
with the literature data.
Note de contenu : Annexes. Diplôme : Doctorat en sciences En ligne : ../theses/chimie/BAA7824.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11656 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BAA/7824 BAA/7824 Thèse Bibliothèque principale Thèses Disponible
Titre : Recherche et détermination structurale des métabolites secondaires et évaluation de l’activité biologique d’une espèce de la famille Scrophulariaceae : Linaria scariosa Desf. Type de document : texte imprimé Auteurs : Meroua Ahmed Chaouch, Auteur ; Ramdane Seghiri, Directeur de thèse Mention d'édition : 15-oct-19 Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2019 Importance : 245 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique : Analyses Physicochimiques, Contrôle de la Qualité et Synthèse de Substances Bioactives Linaria scariosa Desf. étude phytochimique iridoïdes antioxydante anticholinestérase antibactérienne α-glucosidase " Phytochemical study iridoids antioxidant anticholinesterase antibacterial Lianaria scariosa Desfالدراسة الفیتو كیمیائیة إیریدویدات المضاد للأكسدة المضادة
للكولینستیراز مضادة للبكتیریا الفا-غلوكزیداIndex. décimale : 540 Chimie et sciences connexes Résumé :
A bibliographic search on the genus Linaria (Scrophulariaceae) shows that this genus is reputed to accumulate a diversity of secondary metabolites, in particular iridoids and flavonoids, molecules known for their various biological activities. In this work, our interest focused on the phytochemical and biological study of an Algerian species, Linaria scariosa (Scrophulariaceae). The endemism of this specie for Algeria and Tunisia has encouraged us to start this work, especially since this plant has never been studied. The study began with the evaluation of the chemical composition by GC / MS which showed a richness in iridoids, which is in good agreement with the chemotaxonomy of the family Scrophulariaceae. The various chromatographic separation methods used in our experiment made it possible to isolate, from the ethyl acetate and n-butanol extracts, 10 compounds : four iridoids, five
flavonoids and one sterol. Among the isolated compounds, one new iridoid named 6-O-transcinnamoylantirrinoside, and two new flavonoids named desmethoxycentauriedin-7-O-β-neohesperidoside and desmethoxycentauriedin-7-O-α-rhamnopyranosyl(1’’’’→2’’)-β-rutinoside. The structural elucidation of the isolated compounds was carried out by analyzing the UVVisible, NMR1D (1H, 13C and DEPT) and 2D (HSQC, HMBC, COSY and NOESY) spectra and comparing with the data of the literature. The biological activity tests: antioxidant (in vitro), anticholinesterase (in vitro), and antibacterial (in vitro) performed on the extracts, show that the species exhibit remarkable antioxidant and anticholinesterase activity. The inhibitory activity of α-glucosidase performed on the three new products indicates that the new iridoids has a remarkable inhibitory effect on α-glucosidase.
Note de contenu :
Annexe.Diplôme : Doctorat En ligne : ../theses/chimie/AHM7562.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11400 Recherche et détermination structurale des métabolites secondaires et évaluation de l’activité biologique d’une espèce de la famille Scrophulariaceae : Linaria scariosa Desf. [texte imprimé] / Meroua Ahmed Chaouch, Auteur ; Ramdane Seghiri, Directeur de thèse . - 15-oct-19 . - جامعة الإخوة منتوري قسنطينة, 2019 . - 245 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique : Analyses Physicochimiques, Contrôle de la Qualité et Synthèse de Substances Bioactives Linaria scariosa Desf. étude phytochimique iridoïdes antioxydante anticholinestérase antibactérienne α-glucosidase " Phytochemical study iridoids antioxidant anticholinesterase antibacterial Lianaria scariosa Desfالدراسة الفیتو كیمیائیة إیریدویدات المضاد للأكسدة المضادة
للكولینستیراز مضادة للبكتیریا الفا-غلوكزیداIndex. décimale : 540 Chimie et sciences connexes Résumé :
A bibliographic search on the genus Linaria (Scrophulariaceae) shows that this genus is reputed to accumulate a diversity of secondary metabolites, in particular iridoids and flavonoids, molecules known for their various biological activities. In this work, our interest focused on the phytochemical and biological study of an Algerian species, Linaria scariosa (Scrophulariaceae). The endemism of this specie for Algeria and Tunisia has encouraged us to start this work, especially since this plant has never been studied. The study began with the evaluation of the chemical composition by GC / MS which showed a richness in iridoids, which is in good agreement with the chemotaxonomy of the family Scrophulariaceae. The various chromatographic separation methods used in our experiment made it possible to isolate, from the ethyl acetate and n-butanol extracts, 10 compounds : four iridoids, five
flavonoids and one sterol. Among the isolated compounds, one new iridoid named 6-O-transcinnamoylantirrinoside, and two new flavonoids named desmethoxycentauriedin-7-O-β-neohesperidoside and desmethoxycentauriedin-7-O-α-rhamnopyranosyl(1’’’’→2’’)-β-rutinoside. The structural elucidation of the isolated compounds was carried out by analyzing the UVVisible, NMR1D (1H, 13C and DEPT) and 2D (HSQC, HMBC, COSY and NOESY) spectra and comparing with the data of the literature. The biological activity tests: antioxidant (in vitro), anticholinesterase (in vitro), and antibacterial (in vitro) performed on the extracts, show that the species exhibit remarkable antioxidant and anticholinesterase activity. The inhibitory activity of α-glucosidase performed on the three new products indicates that the new iridoids has a remarkable inhibitory effect on α-glucosidase.
Note de contenu :
Annexe.Diplôme : Doctorat En ligne : ../theses/chimie/AHM7562.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11400 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité AHM/7562 AHM/7562 Thèse Bibliothèque principale Thèses Disponible
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