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Partager le résultat de cette recherche Interroger des sources externesComposants et potentiel biologique de Cotula anthemoides L et Pentzia monodiana MAIRE. (Asteraceae). / Wafa Tadrent ép Laouadi
Titre : Composants et potentiel biologique de Cotula anthemoides L et Pentzia monodiana MAIRE. (Asteraceae). Type de document : texte imprimé Auteurs : Wafa Tadrent ép Laouadi, Auteur ; Zahia Kabouche, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 233 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Cotula anthemoides L Pentzia monodiana Maire Asteraceae lignanes flavonoïdes sesquiterpènes lactones activité antioxydante activité anticholinesterase activité
antityrosinase sesquiterpenes lactones antioxidant activity anticholinesterase activity antityrosinase activity ?????????? lignanes?? ??????? ?? ???????????? ? ?? ???????????Index. décimale : 540 Chimie et sciences connexes Résumé : The present work concerns the phytochemical and biological studies of areal parts of two Algerian plants belonging to the Asteraceae family: Cotula anthemoides L. and Pentzia monodiana Maire. This study led to the isolation and identification of fifteen compounds of Cotula anthemoides and eight compounds of Pentzia monodiana including five phenolic acids, nine flavonoids from which one is new, three lignans, one sesquiterpene lactone, two glycosyl phenolics, a glycosyl acid, a diterpene and an nucleoside. The structural determination of the isolated compounds was established by the use of 1D and 2D NMR spectroscopic techniques (1H, 13C, COSY, HSQC, HMBC and ROESY), by mass spectrometry (ESI-MS and HRESI-MS) and by comparison with the literature data. The evaluation of the antioxidant activity by 4 methods (DPPH, ABTS, CUPRAC and chelating by ferrous ions) of the various extracts, showed a good activity of extracts from P. monodiana compared to those of C. anthemoides. Furthermore, extracts of C. anthemoides showed an interesting anticholinesterase activity. However, both of lignanes, flavonol and flavones substituted in C-3, exhibited better antityrosinase and antiradical activities than some flavones only.
Diplôme : Doctorat En ligne : ../theses/chimie/TAD7353.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=11002 Composants et potentiel biologique de Cotula anthemoides L et Pentzia monodiana MAIRE. (Asteraceae). [texte imprimé] / Wafa Tadrent ép Laouadi, Auteur ; Zahia Kabouche, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2018 . - 233 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Cotula anthemoides L Pentzia monodiana Maire Asteraceae lignanes flavonoïdes sesquiterpènes lactones activité antioxydante activité anticholinesterase activité
antityrosinase sesquiterpenes lactones antioxidant activity anticholinesterase activity antityrosinase activity ?????????? lignanes?? ??????? ?? ???????????? ? ?? ???????????Index. décimale : 540 Chimie et sciences connexes Résumé : The present work concerns the phytochemical and biological studies of areal parts of two Algerian plants belonging to the Asteraceae family: Cotula anthemoides L. and Pentzia monodiana Maire. This study led to the isolation and identification of fifteen compounds of Cotula anthemoides and eight compounds of Pentzia monodiana including five phenolic acids, nine flavonoids from which one is new, three lignans, one sesquiterpene lactone, two glycosyl phenolics, a glycosyl acid, a diterpene and an nucleoside. The structural determination of the isolated compounds was established by the use of 1D and 2D NMR spectroscopic techniques (1H, 13C, COSY, HSQC, HMBC and ROESY), by mass spectrometry (ESI-MS and HRESI-MS) and by comparison with the literature data. The evaluation of the antioxidant activity by 4 methods (DPPH, ABTS, CUPRAC and chelating by ferrous ions) of the various extracts, showed a good activity of extracts from P. monodiana compared to those of C. anthemoides. Furthermore, extracts of C. anthemoides showed an interesting anticholinesterase activity. However, both of lignanes, flavonol and flavones substituted in C-3, exhibited better antityrosinase and antiradical activities than some flavones only.
Diplôme : Doctorat En ligne : ../theses/chimie/TAD7353.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=11002 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité TAD/7353 TAD/7353 Thèse Bibliothèque principale Thèses Disponible
Titre : Détermination structurale et évaluation biologique de substances naturelles de quelques espèces de la famille Asteraceae : Senecio giganteus Desf. et Chrysantemum myconis L. Type de document : texte imprimé Auteurs : Nadjet Mezache ; Université Mentouri, Editeur scientifique ; Salah Akkal, Directeur de thèse Année de publication : 2010 Importance : 188 f. Note générale : 01 Disponible à la salle de recherche 01 Disponible au magazin de la B.U.C. 01 CD Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Flavonoides Activité antimicrobienne Coumarine Asteraceae Senecio Chrysanthemum Acides phénoliques Quinones Chromatographie de partage centrifuge Activité anti-oxydante Index. décimale : 540 Chimie et sciences connexes En ligne : ../theses/chimie/MEZ5826.pdf Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=3704 Détermination structurale et évaluation biologique de substances naturelles de quelques espèces de la famille Asteraceae : Senecio giganteus Desf. et Chrysantemum myconis L. [texte imprimé] / Nadjet Mezache ; Université Mentouri, Editeur scientifique ; Salah Akkal, Directeur de thèse . - 2010 . - 188 f.
01 Disponible à la salle de recherche 01 Disponible au magazin de la B.U.C. 01 CD
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Flavonoides Activité antimicrobienne Coumarine Asteraceae Senecio Chrysanthemum Acides phénoliques Quinones Chromatographie de partage centrifuge Activité anti-oxydante Index. décimale : 540 Chimie et sciences connexes En ligne : ../theses/chimie/MEZ5826.pdf Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=3704 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité MEZ/5826 MEZ/5826 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude phytochimique et biologique des espèces Chrysanthemum segetum L. (Asteraceae) et Limonium pruinosum (L.) Chaz. (Plumbaginaceae). Type de document : texte imprimé Auteurs : Samira Kennouche, Auteur ; Ali Bentamene, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 199 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Astéraceae Plumbaginaceae Chrysanthemum Limonium phytochimique flavonoïdes coumarines spectroscopiques antioxydante phytochemical flavonoids coumarins spectroscopic antioxidant ??????? ????????? ?????????????? ??????????? ???? ??????? Index. décimale : 540 Chimie et sciences connexes Résumé : This work was devoted to the phytochemical and biological studies of two plants species belonging to the Asteraceae family (Chrysanthemum segetum L.) and Plumbaginaceae family (Limonium pruinosum L.).
The phytochemical study of the chloroform extract, of aerial parts of Crysanthemum segetum has allowed us to isolate and identify seven compounds, three polyacetylenes, a flavonoid, two sterols and an aromatic ester. Six of them were isolated for the first time from this species.
Analysis of ethyl acetate and n-butanol extracts of Chrysanthemum segetum by the UHPLCMS technique enabled us to propose the molecular structures of twenty-seven phenolic compounds present in these extracts, the major part of these compounds are flavonoids and coumarins.
In the phytochemical study of ethyl acetate and n-butanol extracts of Limonium pruinosum species, five compounds were identified: two flavonoids, an aromatic ester, a cyclitol and a methylglucoside. These compounds have been described for the first time in this species.
The structures of the compounds have been elucidated mainly by the use of spectroscopic techniques, NMR 1-D and 2-D, UV-Vis, mass spectrometry and comparison with literature data.
In the biological part of our work, the antioxidant capacity of ethyl acetate extract and the flavonoids isolated of Limonium pruinosum species was evaluated in vitro by DPPH test, the ethyl acetate extract showed an interesting antioxidant activity compared to standard.
The antioxidant activities of crude extracts of Chrysanthemum segetum species were evaluated by using two methods, DPPH radical scavenging activity and the CUPRAC method, the results showed that the ethyl acetate extract had the highest activity compared to the other extracts tested.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/KEN7010.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10378 Etude phytochimique et biologique des espèces Chrysanthemum segetum L. (Asteraceae) et Limonium pruinosum (L.) Chaz. (Plumbaginaceae). [texte imprimé] / Samira Kennouche, Auteur ; Ali Bentamene, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2017 . - 199 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Astéraceae Plumbaginaceae Chrysanthemum Limonium phytochimique flavonoïdes coumarines spectroscopiques antioxydante phytochemical flavonoids coumarins spectroscopic antioxidant ??????? ????????? ?????????????? ??????????? ???? ??????? Index. décimale : 540 Chimie et sciences connexes Résumé : This work was devoted to the phytochemical and biological studies of two plants species belonging to the Asteraceae family (Chrysanthemum segetum L.) and Plumbaginaceae family (Limonium pruinosum L.).
The phytochemical study of the chloroform extract, of aerial parts of Crysanthemum segetum has allowed us to isolate and identify seven compounds, three polyacetylenes, a flavonoid, two sterols and an aromatic ester. Six of them were isolated for the first time from this species.
Analysis of ethyl acetate and n-butanol extracts of Chrysanthemum segetum by the UHPLCMS technique enabled us to propose the molecular structures of twenty-seven phenolic compounds present in these extracts, the major part of these compounds are flavonoids and coumarins.
In the phytochemical study of ethyl acetate and n-butanol extracts of Limonium pruinosum species, five compounds were identified: two flavonoids, an aromatic ester, a cyclitol and a methylglucoside. These compounds have been described for the first time in this species.
The structures of the compounds have been elucidated mainly by the use of spectroscopic techniques, NMR 1-D and 2-D, UV-Vis, mass spectrometry and comparison with literature data.
In the biological part of our work, the antioxidant capacity of ethyl acetate extract and the flavonoids isolated of Limonium pruinosum species was evaluated in vitro by DPPH test, the ethyl acetate extract showed an interesting antioxidant activity compared to standard.
The antioxidant activities of crude extracts of Chrysanthemum segetum species were evaluated by using two methods, DPPH radical scavenging activity and the CUPRAC method, the results showed that the ethyl acetate extract had the highest activity compared to the other extracts tested.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/KEN7010.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10378 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEN/7010 KEN/7010 Thèse Bibliothèque principale Thèses Disponible
Titre : Étude phytochimique et évaluation des activités antioxydante, antibactérienne et cytotoxique de deux plantes du genre Phagnalon (Asteraceae) Type de document : texte imprimé Auteurs : Hanene Cherchar ép Saadi, Auteur ; Djemaa Berrehal, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 190 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Asteraceae Phagnalon saxatile Phagnalon sordidum activité antioxydante activité antibactérienne cytotoxicité antioxidant activity antibacterial activity cytotoxicity ?????? ????? ??????? ?????? ????? ????????? ?????? ??????? Index. décimale : 540 Chimie et sciences connexes Résumé : Our phytochemical and biological works concerned the aerial parts of two species belonging to Asteraeae family : Phagnalon saxatile (L) Cass. and Phagnalon sordidum L.
Several chromatographic methods allowed us to isolate ten products from the n-butanol and ethyl acetate extracts of Phagnalon saxatile from which one is new, and twenty one products from Phagnalon sordidum.
Structures were determined by different spectral methods: nuclear magnetic resonance with different applications (NMR 1H, NMR 13C, COSY, HSQC and HMBC), the mass spectrometry, UV, acid hydrolysis as well as comparison with literature data.
4 methods were used to evaluate the antioxidant activity of Phagnalon sordidum and Phagnalon saxatile. The latter showed a good activity by the use of 4 methods: DPPH, ABTS, CUPRAC and superoxide radical scavenging activity by alkaline DMSO whereas Phagnalon sordidum exhibited a moderate activity with DPPH and CUPRAC tests.
Furthermore, petroleum ether and chloroform extracts from Phagnalon saxatile showed moderate antibacterial activity against the tested strains. The isolated products (1-O- β-D-glucopyranosyl-1,4-dihydroxy-2-((E) 2-oxo-3-butenyl) benzene, 1-O-β-glucopyranosyl- 2(3’,3’-diméthylallyl) hydroquinone and Potassium 4-hydroxy-3-methoxybenzoique acide
methyl ester-5-sulfate) from Phagnalon saxatile showed a moderate cytotoxic activity by the use of MTT method.
Diplôme : Doctorat En ligne : ../theses/chimie/CHE7249.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10841 Étude phytochimique et évaluation des activités antioxydante, antibactérienne et cytotoxique de deux plantes du genre Phagnalon (Asteraceae) [texte imprimé] / Hanene Cherchar ép Saadi, Auteur ; Djemaa Berrehal, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2018 . - 190 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Asteraceae Phagnalon saxatile Phagnalon sordidum activité antioxydante activité antibactérienne cytotoxicité antioxidant activity antibacterial activity cytotoxicity ?????? ????? ??????? ?????? ????? ????????? ?????? ??????? Index. décimale : 540 Chimie et sciences connexes Résumé : Our phytochemical and biological works concerned the aerial parts of two species belonging to Asteraeae family : Phagnalon saxatile (L) Cass. and Phagnalon sordidum L.
Several chromatographic methods allowed us to isolate ten products from the n-butanol and ethyl acetate extracts of Phagnalon saxatile from which one is new, and twenty one products from Phagnalon sordidum.
Structures were determined by different spectral methods: nuclear magnetic resonance with different applications (NMR 1H, NMR 13C, COSY, HSQC and HMBC), the mass spectrometry, UV, acid hydrolysis as well as comparison with literature data.
4 methods were used to evaluate the antioxidant activity of Phagnalon sordidum and Phagnalon saxatile. The latter showed a good activity by the use of 4 methods: DPPH, ABTS, CUPRAC and superoxide radical scavenging activity by alkaline DMSO whereas Phagnalon sordidum exhibited a moderate activity with DPPH and CUPRAC tests.
Furthermore, petroleum ether and chloroform extracts from Phagnalon saxatile showed moderate antibacterial activity against the tested strains. The isolated products (1-O- β-D-glucopyranosyl-1,4-dihydroxy-2-((E) 2-oxo-3-butenyl) benzene, 1-O-β-glucopyranosyl- 2(3’,3’-diméthylallyl) hydroquinone and Potassium 4-hydroxy-3-methoxybenzoique acide
methyl ester-5-sulfate) from Phagnalon saxatile showed a moderate cytotoxic activity by the use of MTT method.
Diplôme : Doctorat En ligne : ../theses/chimie/CHE7249.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10841 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité CHE/7249 CHE/7249 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude phytochimique et pharmacologique de plantes médicinales Algériennes Genista ulicina Spach (Fabaceae) et Chrysanthemum macrocarpum (Sch. Bip.) Coss. & Kralik ex Batt (Asteraceae) Type de document : texte imprimé Auteurs : Naima Boutaghane, Auteur ; Zahia Kabouche, Directeur de thèse ; Laurence Voutquenne, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2013 Importance : 270 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Fabaceae Asteraceae Genista ulicina Chrysanthemum macrocarpum cyclitols Saponines flavonoïdes Huile essentielle activités biologiques RMN 1D et 2D Spectrométrie de masse Saponins flavonoids essential oil biological activities NMR 1D and 2D mass spectroscopy ????????? ???????????? ?????? ??????? ??????? ?????? ?????? ?????????? ?????? ? ?????? ????? ??????? ?????? Index. décimale : 540 Chimie et sciences connexes Résumé :
This report is concerning the phytochemical study of two Algerian plants belonging to the Fabaceae family (Genista ulicina Spach) and Asteraceae family (Chrysanthemum macrocarpum Coss. & Kralik ex Batt). This study led to the isolation and identification of 36 compounds from which 10 compounds are new.
The structures of isolated compounds were established particularly by the use of NMR highfield
1D and 2D technics (1H, 13C J-modulated, COSY H-H, HSQC J-modulated, HMBC and NOESY), high resolution mass spectrometry (ESI-MS and HR-ESI-MS), measurement of rotatory power and comparison with literature data.
GC and GC / MS analyses of the essential oil of C. macrocarpum showed that it was mainly represented by: T-cadinol (19.6%), spathulenol (12.5%), caryophyllene oxide (6.5%), and α- cadinol (5.6%).
The chloroform fraction of C. macrocarpum showed a weak antibacterial activity against: E.
coli, S. aureus, P.aeruginosa, E. faecalis and K. pneumoniae.
The same chloroform fraction was evaluated for its antiproliferative activity against human cancer HT-29 cells and human PC3 cells. The results indicate that the chloroform fraction inhibited cell proliferation of both HT-29 and PC-3 cells,The chloroform fraction showed an excellent analegesic, anti-inflammatory and antiulcerogenic activities.
The butanolic fraction of G. ulicina and isolated compounds were investigated for their antibacterial and antiproliferative growth inhibition, but no significant activities were observed.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/BOU6343.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6313 Etude phytochimique et pharmacologique de plantes médicinales Algériennes Genista ulicina Spach (Fabaceae) et Chrysanthemum macrocarpum (Sch. Bip.) Coss. & Kralik ex Batt (Asteraceae) [texte imprimé] / Naima Boutaghane, Auteur ; Zahia Kabouche, Directeur de thèse ; Laurence Voutquenne, Directeur de thèse . - constantine (Route ain el bey, Algérie) : Université Constantine 1, 2013 . - 270 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Fabaceae Asteraceae Genista ulicina Chrysanthemum macrocarpum cyclitols Saponines flavonoïdes Huile essentielle activités biologiques RMN 1D et 2D Spectrométrie de masse Saponins flavonoids essential oil biological activities NMR 1D and 2D mass spectroscopy ????????? ???????????? ?????? ??????? ??????? ?????? ?????? ?????????? ?????? ? ?????? ????? ??????? ?????? Index. décimale : 540 Chimie et sciences connexes Résumé :
This report is concerning the phytochemical study of two Algerian plants belonging to the Fabaceae family (Genista ulicina Spach) and Asteraceae family (Chrysanthemum macrocarpum Coss. & Kralik ex Batt). This study led to the isolation and identification of 36 compounds from which 10 compounds are new.
The structures of isolated compounds were established particularly by the use of NMR highfield
1D and 2D technics (1H, 13C J-modulated, COSY H-H, HSQC J-modulated, HMBC and NOESY), high resolution mass spectrometry (ESI-MS and HR-ESI-MS), measurement of rotatory power and comparison with literature data.
GC and GC / MS analyses of the essential oil of C. macrocarpum showed that it was mainly represented by: T-cadinol (19.6%), spathulenol (12.5%), caryophyllene oxide (6.5%), and α- cadinol (5.6%).
The chloroform fraction of C. macrocarpum showed a weak antibacterial activity against: E.
coli, S. aureus, P.aeruginosa, E. faecalis and K. pneumoniae.
The same chloroform fraction was evaluated for its antiproliferative activity against human cancer HT-29 cells and human PC3 cells. The results indicate that the chloroform fraction inhibited cell proliferation of both HT-29 and PC-3 cells,The chloroform fraction showed an excellent analegesic, anti-inflammatory and antiulcerogenic activities.
The butanolic fraction of G. ulicina and isolated compounds were investigated for their antibacterial and antiproliferative growth inhibition, but no significant activities were observed.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/BOU6343.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=6313 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BOU/6343 BOU/6343 Thèse Bibliothèque principale Thèses Disponible
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