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'antioxydante' 




Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. / Sara Himour ép Cherrier
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Titre : Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. Type de document : texte imprimé Auteurs : Sara Himour ép Cherrier, Auteur ; Abdelouahab Yahia, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 209 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Olea europaea L. morphologie physiologie HPLC Oleuropéine activité biologique antioxydante anticoagulante antibactérienne morphology physiology Oleuropein biological activity antioxidant anticoagulant antibacterial اولیااوروبیا Lمورفولوجیا، فیزیولوجیة HPLCأولیوروبین النشاط البیولوجي مضادات الأكسدة مضاد للتخثر مضاد
للبكتیریاIndex. décimale : 570 Sciences de la vie. Biologie Résumé : The present study focuses on the biological, physiological and biochemical behavior of the cultivated olive tree, Olea europaea L., represented by four varieties sampled at the Maazouzi Lakhdar station, Mila: Sigoise, Rougette, Chemlel and Dathier. The morphological characterizations (quantitative and qualitative), relating to the leaves, fruits and cores, described in the descriptors of the International Olive Council (IOC, 2003), revealed differences between the varieties. The set of morphological traits assessed during the three years of study (2013-2014- 2015) revealed a significant difference between the varieties studied confirmed by coefficients of
variation ranging from 2.81% to 39.14%. Positive correlations between mean precipitation, duration of insolations and morphological characters ranged from r = 0.839 to 0.946, and negative for fruit width and nuclei with temperature.
The results of the analysis of the biochemical characterization data revealed a great difference between the varieties. The most important lipid content was recorded in Sigoise leaf and fruit, Rougette gave the best sugar content in the leaves, as well as in Chemlel fruits. The qualitative analysis performed by phytochemical screening revealed the presence of several families of natural compounds in both organs. Rougette has been the dominant variety for total leaf and fruit phenol and flavonoid content, and Dathier for tannins. Quantitative analyzes of the phenolic compounds identified in the hydromethanol extracts by HPLC identified four
compounds: fumaric acid, gallic acid, oleuropein and caffeic acid, seven compounds in the leaves: fumaric acid, gallic acid, oleuropein, 4-hydroxybenzoic acid acid, caffeic acid, ellagic acid and t-3 hydroxyroamic acid, with a significant dominance of Oleuropein.
The evaluation of the biological potential of leaf and fruit extracts, revealed a significant anticoagulant activity in Chemlel for both organs and an antioxidant power of interest in Rougette leaves and Sigois fruits. All extracts have an important antibacterial power, extracts of leaf at Rougette gave a better zone of inhibition against S. aureus.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HIM7315.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10931 Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. [texte imprimé] / Sara Himour ép Cherrier, Auteur ; Abdelouahab Yahia, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 209 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Olea europaea L. morphologie physiologie HPLC Oleuropéine activité biologique antioxydante anticoagulante antibactérienne morphology physiology Oleuropein biological activity antioxidant anticoagulant antibacterial اولیااوروبیا Lمورفولوجیا، فیزیولوجیة HPLCأولیوروبین النشاط البیولوجي مضادات الأكسدة مضاد للتخثر مضاد
للبكتیریاIndex. décimale : 570 Sciences de la vie. Biologie Résumé : The present study focuses on the biological, physiological and biochemical behavior of the cultivated olive tree, Olea europaea L., represented by four varieties sampled at the Maazouzi Lakhdar station, Mila: Sigoise, Rougette, Chemlel and Dathier. The morphological characterizations (quantitative and qualitative), relating to the leaves, fruits and cores, described in the descriptors of the International Olive Council (IOC, 2003), revealed differences between the varieties. The set of morphological traits assessed during the three years of study (2013-2014- 2015) revealed a significant difference between the varieties studied confirmed by coefficients of
variation ranging from 2.81% to 39.14%. Positive correlations between mean precipitation, duration of insolations and morphological characters ranged from r = 0.839 to 0.946, and negative for fruit width and nuclei with temperature.
The results of the analysis of the biochemical characterization data revealed a great difference between the varieties. The most important lipid content was recorded in Sigoise leaf and fruit, Rougette gave the best sugar content in the leaves, as well as in Chemlel fruits. The qualitative analysis performed by phytochemical screening revealed the presence of several families of natural compounds in both organs. Rougette has been the dominant variety for total leaf and fruit phenol and flavonoid content, and Dathier for tannins. Quantitative analyzes of the phenolic compounds identified in the hydromethanol extracts by HPLC identified four
compounds: fumaric acid, gallic acid, oleuropein and caffeic acid, seven compounds in the leaves: fumaric acid, gallic acid, oleuropein, 4-hydroxybenzoic acid acid, caffeic acid, ellagic acid and t-3 hydroxyroamic acid, with a significant dominance of Oleuropein.
The evaluation of the biological potential of leaf and fruit extracts, revealed a significant anticoagulant activity in Chemlel for both organs and an antioxidant power of interest in Rougette leaves and Sigois fruits. All extracts have an important antibacterial power, extracts of leaf at Rougette gave a better zone of inhibition against S. aureus.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HIM7315.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10931 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité HIM/7315 HIM/7315 Thèse Bibliothèque principale Thèses Disponible Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques / Ilhem Labed ep Zouad
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Titre : Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques Type de document : texte imprimé Auteurs : Ilhem Labed ep Zouad, Auteur ; Zahia Kabouche, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 211 f. Format : 30 cm. Note générale : 2 copies imprimes disponibles Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique Ferula vesceritensis Coss. & Dur. antioxydante anticholinestérase antibactérienne couplage oxydant énamides pipéridines hydroboration hydrogénation Pistacia atlantica Desf. antioxidant anticholinesterase antibacterial oxidative coupling enamides hydrogenation hydrobration piperidines Index. décimale : 540 Chimie et sciences connexes Résumé : In a first part we studied the chemical composition and biological activities of Pistacia
atlantica Desf. and Ferula vesceritensis Coss. & Dur. The GC and GC-MS analyses
showed that the essential oils of P. atlantica are rich in α-pinene, limonene and spatulenol,
while β-phellandrene, α-terpinene, β-elemene, γ-gurjunene and germacrene-B were found
as major components, for the first time for the essential oils of the genus Pistacia .
α-Pinene and β- pinene were predominant in the essential oils of Ferula vesceritensis;
however the first time that α-phellandrene, fenchylacetate, elixene, l'aristolene and cartol
were found as main components in the essential oils of the genus Ferula . The both essential
oils of P. atlantica . and F. vesceritensis exhibited a good antibacterial activity against
clinical isolated bacteria and food borne pathogens. The essential oils of P. atlantica
possess an important antioxidant effect which were determined using β-carotene-linoleic
acid, DPPH- and ABTS•+ -scavenging activities, metal chelating effect and CUPRAC
assays. The essential oils showed a moderate anticholinestérase activity compared with
galantamin for the inhibitory activity of principal enzymes of Alzheimer’s disease AChE
and BChE.
In a second part, we synthesized 12 new piperidine derivatives, which have been achieved
through [Cp*Ru]-catalyzed intermolecular coupling of allylic alcohols and propargylic
amides with water as the only side product, and demonstrated that the selective
oxidativecoupling cinnamyl alcohol derivatives and 2-substituted allylic alcohols. This
methodology allows the access to 3,4- and 3,5-disubstituted enamides as valuable
scaffolds for the preparation of 3-methylpiperidine derivatives through selective [Cp*Ru]
catalyzed alkene hydrogenation.Diplôme : Doctorat En ligne : ../theses/chimie/LAB6834.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10126 Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques [texte imprimé] / Ilhem Labed ep Zouad, Auteur ; Zahia Kabouche, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 211 f. ; 30 cm.
2 copies imprimes disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique Ferula vesceritensis Coss. & Dur. antioxydante anticholinestérase antibactérienne couplage oxydant énamides pipéridines hydroboration hydrogénation Pistacia atlantica Desf. antioxidant anticholinesterase antibacterial oxidative coupling enamides hydrogenation hydrobration piperidines Index. décimale : 540 Chimie et sciences connexes Résumé : In a first part we studied the chemical composition and biological activities of Pistacia
atlantica Desf. and Ferula vesceritensis Coss. & Dur. The GC and GC-MS analyses
showed that the essential oils of P. atlantica are rich in α-pinene, limonene and spatulenol,
while β-phellandrene, α-terpinene, β-elemene, γ-gurjunene and germacrene-B were found
as major components, for the first time for the essential oils of the genus Pistacia .
α-Pinene and β- pinene were predominant in the essential oils of Ferula vesceritensis;
however the first time that α-phellandrene, fenchylacetate, elixene, l'aristolene and cartol
were found as main components in the essential oils of the genus Ferula . The both essential
oils of P. atlantica . and F. vesceritensis exhibited a good antibacterial activity against
clinical isolated bacteria and food borne pathogens. The essential oils of P. atlantica
possess an important antioxidant effect which were determined using β-carotene-linoleic
acid, DPPH- and ABTS•+ -scavenging activities, metal chelating effect and CUPRAC
assays. The essential oils showed a moderate anticholinestérase activity compared with
galantamin for the inhibitory activity of principal enzymes of Alzheimer’s disease AChE
and BChE.
In a second part, we synthesized 12 new piperidine derivatives, which have been achieved
through [Cp*Ru]-catalyzed intermolecular coupling of allylic alcohols and propargylic
amides with water as the only side product, and demonstrated that the selective
oxidativecoupling cinnamyl alcohol derivatives and 2-substituted allylic alcohols. This
methodology allows the access to 3,4- and 3,5-disubstituted enamides as valuable
scaffolds for the preparation of 3-methylpiperidine derivatives through selective [Cp*Ru]
catalyzed alkene hydrogenation.Diplôme : Doctorat En ligne : ../theses/chimie/LAB6834.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10126 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité LAB/6834 LAB/6834 Thèse Bibliothèque principale Thèses Disponible Etude du contenu polyphénolique de deux plantes médicinales d'intérêt économique (Thymus vulgaris, Rosmarinus officinalis) et évaluation de leur activité antibactérienne
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Titre : Etude du contenu polyphénolique de deux plantes médicinales d'intérêt économique (Thymus vulgaris, Rosmarinus officinalis) et évaluation de leur activité antibactérienne Type de document : texte imprimé Auteurs : Univ. de Constantine, Éditeur scientifique Année de publication : 2009 Importance : 96 f. Note générale : 01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Flavonoides Rosmarinus officinalis Thymus vulgaris Antioxydante Antibactérienne Index. décimale : 570 Sciences de la vie. Biologie En ligne : ../theses/biologie/ZEG5532.pdf Permalink : index.php?lvl=notice_display&id=1808 Etude du contenu polyphénolique de deux plantes médicinales d'intérêt économique (Thymus vulgaris, Rosmarinus officinalis) et évaluation de leur activité antibactérienne [texte imprimé] / Univ. de Constantine, Éditeur scientifique . - 2009 . - 96 f.
01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Flavonoides Rosmarinus officinalis Thymus vulgaris Antioxydante Antibactérienne Index. décimale : 570 Sciences de la vie. Biologie En ligne : ../theses/biologie/ZEG5532.pdf Permalink : index.php?lvl=notice_display&id=1808 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité ZEG/5532 ZEG/5532 Thèse Bibliothèque principale Thèses Disponible Etude phytochimique et biologique de Bituminaria bituminosa(L.)C.H.Stirton (Fabaceae) et Centaaurea dimorphaViv. (Asteraceae) / Salima Azzouzi ep Ouchtati
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Titre : Etude phytochimique et biologique de Bituminaria bituminosa(L.)C.H.Stirton (Fabaceae) et Centaaurea dimorphaViv. (Asteraceae) Type de document : texte imprimé Auteurs : Salima Azzouzi ep Ouchtati, Auteur ; Kamel Medjroubi, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 135 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Fabaceae Asteracea Bituminaria bituminosa Centaurea dimorpha antioxydante activité antibactérienne antioxidant antibacterial activity العائلة الباقولیة العائلة المركبة مضادة للاكسدة فعالیة مضادة للبكتیریا Index. décimale : 540 Chimie et sciences connexes Résumé : Our research includes the stady of the phytochemical and biological aspects of the two presented species Bituminaria bituminosa(L.) C.H.Stirton. which belongs to Fabaceae family and Centaurea dimorpha Viv. which belongs to Asteraceae family.
Several chromatographic methods were used in our work. Thes methods allowed us to isolate four products from B.bituminosa plant (only three have been identified), and five products from C.dimorpha plant (only four have been identified).
The identification of structures has been realised by combining the different spectrometric and spectroscopic methods (SMES, UV, RMN-1D,2D).
Butanolic extract of B.bituminosa species showed a weak antioxidant capacity. The various extracts of the two studied plants have shown a good antibacterial activity.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/AZZ6871.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10185 Etude phytochimique et biologique de Bituminaria bituminosa(L.)C.H.Stirton (Fabaceae) et Centaaurea dimorphaViv. (Asteraceae) [texte imprimé] / Salima Azzouzi ep Ouchtati, Auteur ; Kamel Medjroubi, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 135 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Fabaceae Asteracea Bituminaria bituminosa Centaurea dimorpha antioxydante activité antibactérienne antioxidant antibacterial activity العائلة الباقولیة العائلة المركبة مضادة للاكسدة فعالیة مضادة للبكتیریا Index. décimale : 540 Chimie et sciences connexes Résumé : Our research includes the stady of the phytochemical and biological aspects of the two presented species Bituminaria bituminosa(L.) C.H.Stirton. which belongs to Fabaceae family and Centaurea dimorpha Viv. which belongs to Asteraceae family.
Several chromatographic methods were used in our work. Thes methods allowed us to isolate four products from B.bituminosa plant (only three have been identified), and five products from C.dimorpha plant (only four have been identified).
The identification of structures has been realised by combining the different spectrometric and spectroscopic methods (SMES, UV, RMN-1D,2D).
Butanolic extract of B.bituminosa species showed a weak antioxidant capacity. The various extracts of the two studied plants have shown a good antibacterial activity.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/AZZ6871.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10185 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité AZZ/6871 AZZ/6871 Thèse Bibliothèque principale Thèses Disponible Etude phytochimique et biologique des espèces Chrysanthemum segetum L. (Asteraceae) et Limonium pruinosum (L.) Chaz. (Plumbaginaceae). / Samira Kennouche
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Titre : Etude phytochimique et biologique des espèces Chrysanthemum segetum L. (Asteraceae) et Limonium pruinosum (L.) Chaz. (Plumbaginaceae). Type de document : texte imprimé Auteurs : Samira Kennouche, Auteur ; Ali Bentamene, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 199 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Astéraceae Plumbaginaceae Chrysanthemum Limonium phytochimique flavonoïdes coumarines spectroscopiques antioxydante phytochemical flavonoids coumarins spectroscopic antioxidant المركبة الرصاصيات الفيتوكيميائية الفلافونويد الكومارين مطيافية مضاد للأكسدة Index. décimale : 540 Chimie et sciences connexes Résumé : This work was devoted to the phytochemical and biological studies of two plants species belonging to the Asteraceae family (Chrysanthemum segetum L.) and Plumbaginaceae family (Limonium pruinosum L.).
The phytochemical study of the chloroform extract, of aerial parts of Crysanthemum segetum has allowed us to isolate and identify seven compounds, three polyacetylenes, a flavonoid, two sterols and an aromatic ester. Six of them were isolated for the first time from this species.
Analysis of ethyl acetate and n-butanol extracts of Chrysanthemum segetum by the UHPLCMS technique enabled us to propose the molecular structures of twenty-seven phenolic compounds present in these extracts, the major part of these compounds are flavonoids and coumarins.
In the phytochemical study of ethyl acetate and n-butanol extracts of Limonium pruinosum species, five compounds were identified: two flavonoids, an aromatic ester, a cyclitol and a methylglucoside. These compounds have been described for the first time in this species.
The structures of the compounds have been elucidated mainly by the use of spectroscopic techniques, NMR 1-D and 2-D, UV-Vis, mass spectrometry and comparison with literature data.
In the biological part of our work, the antioxidant capacity of ethyl acetate extract and the flavonoids isolated of Limonium pruinosum species was evaluated in vitro by DPPH test, the ethyl acetate extract showed an interesting antioxidant activity compared to standard.
The antioxidant activities of crude extracts of Chrysanthemum segetum species were evaluated by using two methods, DPPH radical scavenging activity and the CUPRAC method, the results showed that the ethyl acetate extract had the highest activity compared to the other extracts tested.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/KEN7010.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10378 Etude phytochimique et biologique des espèces Chrysanthemum segetum L. (Asteraceae) et Limonium pruinosum (L.) Chaz. (Plumbaginaceae). [texte imprimé] / Samira Kennouche, Auteur ; Ali Bentamene, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2017 . - 199 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Astéraceae Plumbaginaceae Chrysanthemum Limonium phytochimique flavonoïdes coumarines spectroscopiques antioxydante phytochemical flavonoids coumarins spectroscopic antioxidant المركبة الرصاصيات الفيتوكيميائية الفلافونويد الكومارين مطيافية مضاد للأكسدة Index. décimale : 540 Chimie et sciences connexes Résumé : This work was devoted to the phytochemical and biological studies of two plants species belonging to the Asteraceae family (Chrysanthemum segetum L.) and Plumbaginaceae family (Limonium pruinosum L.).
The phytochemical study of the chloroform extract, of aerial parts of Crysanthemum segetum has allowed us to isolate and identify seven compounds, three polyacetylenes, a flavonoid, two sterols and an aromatic ester. Six of them were isolated for the first time from this species.
Analysis of ethyl acetate and n-butanol extracts of Chrysanthemum segetum by the UHPLCMS technique enabled us to propose the molecular structures of twenty-seven phenolic compounds present in these extracts, the major part of these compounds are flavonoids and coumarins.
In the phytochemical study of ethyl acetate and n-butanol extracts of Limonium pruinosum species, five compounds were identified: two flavonoids, an aromatic ester, a cyclitol and a methylglucoside. These compounds have been described for the first time in this species.
The structures of the compounds have been elucidated mainly by the use of spectroscopic techniques, NMR 1-D and 2-D, UV-Vis, mass spectrometry and comparison with literature data.
In the biological part of our work, the antioxidant capacity of ethyl acetate extract and the flavonoids isolated of Limonium pruinosum species was evaluated in vitro by DPPH test, the ethyl acetate extract showed an interesting antioxidant activity compared to standard.
The antioxidant activities of crude extracts of Chrysanthemum segetum species were evaluated by using two methods, DPPH radical scavenging activity and the CUPRAC method, the results showed that the ethyl acetate extract had the highest activity compared to the other extracts tested.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/KEN7010.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10378 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEN/7010 KEN/7010 Thèse Bibliothèque principale Thèses Disponible PermalinkRecherche et détermination structurale des métabolites secondaires et évaluation de l’activité biologique d’une espèce de la famille Scrophulariaceae / Meroua Ahmed Chaouch
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