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Partager le résultat de cette recherche Interroger des sources externesEtude du contenu polyphénolique de deux plantes médicinales d'intérêt économique (Thymus vulgaris, Rosmarinus officinalis) et évaluation de leur activité antibactérienne
Titre : Etude du contenu polyphénolique de deux plantes médicinales d'intérêt économique (Thymus vulgaris, Rosmarinus officinalis) et évaluation de leur activité antibactérienne Type de document : texte imprimé Auteurs : Univ. de Constantine, Éditeur scientifique Année de publication : 2009 Importance : 96 f. Note générale : 01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Flavonoides Rosmarinus officinalis Thymus vulgaris Antioxydante Antibactérienne Index. décimale : 570 Sciences de la vie. Biologie En ligne : ../theses/biologie/ZEG5532.pdf Permalink : index.php?lvl=notice_display&id=1808 Etude du contenu polyphénolique de deux plantes médicinales d'intérêt économique (Thymus vulgaris, Rosmarinus officinalis) et évaluation de leur activité antibactérienne [texte imprimé] / Univ. de Constantine, Éditeur scientifique . - 2009 . - 96 f.
01 Disponible à la salle de recherche 02 Disponibles au magazin de la B.U.C. 01 CD
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Flavonoides Rosmarinus officinalis Thymus vulgaris Antioxydante Antibactérienne Index. décimale : 570 Sciences de la vie. Biologie En ligne : ../theses/biologie/ZEG5532.pdf Permalink : index.php?lvl=notice_display&id=1808 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité ZEG/5532 ZEG/5532 Thèse Bibliothèque principale Thèses Disponible
Titre : Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. Type de document : texte imprimé Auteurs : Sara Himour ép Cherrier, Auteur ; Abdelouahab Yahia, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 209 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Olea europaea L. morphologie physiologie HPLC Oleuropéine activité biologique antioxydante anticoagulante antibactérienne morphology physiology Oleuropein biological activity antioxidant anticoagulant antibacterial اولیااوروبیا Lمورفولوجیا، فیزیولوجیة HPLCأولیوروبین النشاط البیولوجي مضادات الأكسدة مضاد للتخثر مضاد
للبكتیریاIndex. décimale : 570 Sciences de la vie. Biologie Résumé : The present study focuses on the biological, physiological and biochemical behavior of the cultivated olive tree, Olea europaea L., represented by four varieties sampled at the Maazouzi Lakhdar station, Mila: Sigoise, Rougette, Chemlel and Dathier. The morphological characterizations (quantitative and qualitative), relating to the leaves, fruits and cores, described in the descriptors of the International Olive Council (IOC, 2003), revealed differences between the varieties. The set of morphological traits assessed during the three years of study (2013-2014- 2015) revealed a significant difference between the varieties studied confirmed by coefficients of
variation ranging from 2.81% to 39.14%. Positive correlations between mean precipitation, duration of insolations and morphological characters ranged from r = 0.839 to 0.946, and negative for fruit width and nuclei with temperature.
The results of the analysis of the biochemical characterization data revealed a great difference between the varieties. The most important lipid content was recorded in Sigoise leaf and fruit, Rougette gave the best sugar content in the leaves, as well as in Chemlel fruits. The qualitative analysis performed by phytochemical screening revealed the presence of several families of natural compounds in both organs. Rougette has been the dominant variety for total leaf and fruit phenol and flavonoid content, and Dathier for tannins. Quantitative analyzes of the phenolic compounds identified in the hydromethanol extracts by HPLC identified four
compounds: fumaric acid, gallic acid, oleuropein and caffeic acid, seven compounds in the leaves: fumaric acid, gallic acid, oleuropein, 4-hydroxybenzoic acid acid, caffeic acid, ellagic acid and t-3 hydroxyroamic acid, with a significant dominance of Oleuropein.
The evaluation of the biological potential of leaf and fruit extracts, revealed a significant anticoagulant activity in Chemlel for both organs and an antioxidant power of interest in Rougette leaves and Sigois fruits. All extracts have an important antibacterial power, extracts of leaf at Rougette gave a better zone of inhibition against S. aureus.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HIM7315.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10931 Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. [texte imprimé] / Sara Himour ép Cherrier, Auteur ; Abdelouahab Yahia, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 209 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Olea europaea L. morphologie physiologie HPLC Oleuropéine activité biologique antioxydante anticoagulante antibactérienne morphology physiology Oleuropein biological activity antioxidant anticoagulant antibacterial اولیااوروبیا Lمورفولوجیا، فیزیولوجیة HPLCأولیوروبین النشاط البیولوجي مضادات الأكسدة مضاد للتخثر مضاد
للبكتیریاIndex. décimale : 570 Sciences de la vie. Biologie Résumé : The present study focuses on the biological, physiological and biochemical behavior of the cultivated olive tree, Olea europaea L., represented by four varieties sampled at the Maazouzi Lakhdar station, Mila: Sigoise, Rougette, Chemlel and Dathier. The morphological characterizations (quantitative and qualitative), relating to the leaves, fruits and cores, described in the descriptors of the International Olive Council (IOC, 2003), revealed differences between the varieties. The set of morphological traits assessed during the three years of study (2013-2014- 2015) revealed a significant difference between the varieties studied confirmed by coefficients of
variation ranging from 2.81% to 39.14%. Positive correlations between mean precipitation, duration of insolations and morphological characters ranged from r = 0.839 to 0.946, and negative for fruit width and nuclei with temperature.
The results of the analysis of the biochemical characterization data revealed a great difference between the varieties. The most important lipid content was recorded in Sigoise leaf and fruit, Rougette gave the best sugar content in the leaves, as well as in Chemlel fruits. The qualitative analysis performed by phytochemical screening revealed the presence of several families of natural compounds in both organs. Rougette has been the dominant variety for total leaf and fruit phenol and flavonoid content, and Dathier for tannins. Quantitative analyzes of the phenolic compounds identified in the hydromethanol extracts by HPLC identified four
compounds: fumaric acid, gallic acid, oleuropein and caffeic acid, seven compounds in the leaves: fumaric acid, gallic acid, oleuropein, 4-hydroxybenzoic acid acid, caffeic acid, ellagic acid and t-3 hydroxyroamic acid, with a significant dominance of Oleuropein.
The evaluation of the biological potential of leaf and fruit extracts, revealed a significant anticoagulant activity in Chemlel for both organs and an antioxidant power of interest in Rougette leaves and Sigois fruits. All extracts have an important antibacterial power, extracts of leaf at Rougette gave a better zone of inhibition against S. aureus.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HIM7315.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10931 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité HIM/7315 HIM/7315 Thèse Bibliothèque principale Thèses Disponible
Titre : Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques Type de document : texte imprimé Auteurs : Ilhem Labed ep Zouad, Auteur ; Zahia Kabouche, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 211 f. Format : 30 cm. Note générale : 2 copies imprimes disponibles Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique Ferula vesceritensis Coss. & Dur. antioxydante anticholinestérase antibactérienne couplage oxydant énamides pipéridines hydroboration hydrogénation Pistacia atlantica Desf. antioxidant anticholinesterase antibacterial oxidative coupling enamides hydrogenation hydrobration piperidines Index. décimale : 540 Chimie et sciences connexes Résumé : In a first part we studied the chemical composition and biological activities of Pistacia
atlantica Desf. and Ferula vesceritensis Coss. & Dur. The GC and GC-MS analyses
showed that the essential oils of P. atlantica are rich in α-pinene, limonene and spatulenol,
while β-phellandrene, α-terpinene, β-elemene, γ-gurjunene and germacrene-B were found
as major components, for the first time for the essential oils of the genus Pistacia .
α-Pinene and β- pinene were predominant in the essential oils of Ferula vesceritensis;
however the first time that α-phellandrene, fenchylacetate, elixene, l'aristolene and cartol
were found as main components in the essential oils of the genus Ferula . The both essential
oils of P. atlantica . and F. vesceritensis exhibited a good antibacterial activity against
clinical isolated bacteria and food borne pathogens. The essential oils of P. atlantica
possess an important antioxidant effect which were determined using β-carotene-linoleic
acid, DPPH- and ABTS•+ -scavenging activities, metal chelating effect and CUPRAC
assays. The essential oils showed a moderate anticholinestérase activity compared with
galantamin for the inhibitory activity of principal enzymes of Alzheimer’s disease AChE
and BChE.
In a second part, we synthesized 12 new piperidine derivatives, which have been achieved
through [Cp*Ru]-catalyzed intermolecular coupling of allylic alcohols and propargylic
amides with water as the only side product, and demonstrated that the selective
oxidativecoupling cinnamyl alcohol derivatives and 2-substituted allylic alcohols. This
methodology allows the access to 3,4- and 3,5-disubstituted enamides as valuable
scaffolds for the preparation of 3-methylpiperidine derivatives through selective [Cp*Ru]
catalyzed alkene hydrogenation.Diplôme : Doctorat En ligne : ../theses/chimie/LAB6834.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10126 Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques [texte imprimé] / Ilhem Labed ep Zouad, Auteur ; Zahia Kabouche, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 211 f. ; 30 cm.
2 copies imprimes disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique Ferula vesceritensis Coss. & Dur. antioxydante anticholinestérase antibactérienne couplage oxydant énamides pipéridines hydroboration hydrogénation Pistacia atlantica Desf. antioxidant anticholinesterase antibacterial oxidative coupling enamides hydrogenation hydrobration piperidines Index. décimale : 540 Chimie et sciences connexes Résumé : In a first part we studied the chemical composition and biological activities of Pistacia
atlantica Desf. and Ferula vesceritensis Coss. & Dur. The GC and GC-MS analyses
showed that the essential oils of P. atlantica are rich in α-pinene, limonene and spatulenol,
while β-phellandrene, α-terpinene, β-elemene, γ-gurjunene and germacrene-B were found
as major components, for the first time for the essential oils of the genus Pistacia .
α-Pinene and β- pinene were predominant in the essential oils of Ferula vesceritensis;
however the first time that α-phellandrene, fenchylacetate, elixene, l'aristolene and cartol
were found as main components in the essential oils of the genus Ferula . The both essential
oils of P. atlantica . and F. vesceritensis exhibited a good antibacterial activity against
clinical isolated bacteria and food borne pathogens. The essential oils of P. atlantica
possess an important antioxidant effect which were determined using β-carotene-linoleic
acid, DPPH- and ABTS•+ -scavenging activities, metal chelating effect and CUPRAC
assays. The essential oils showed a moderate anticholinestérase activity compared with
galantamin for the inhibitory activity of principal enzymes of Alzheimer’s disease AChE
and BChE.
In a second part, we synthesized 12 new piperidine derivatives, which have been achieved
through [Cp*Ru]-catalyzed intermolecular coupling of allylic alcohols and propargylic
amides with water as the only side product, and demonstrated that the selective
oxidativecoupling cinnamyl alcohol derivatives and 2-substituted allylic alcohols. This
methodology allows the access to 3,4- and 3,5-disubstituted enamides as valuable
scaffolds for the preparation of 3-methylpiperidine derivatives through selective [Cp*Ru]
catalyzed alkene hydrogenation.Diplôme : Doctorat En ligne : ../theses/chimie/LAB6834.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10126 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité LAB/6834 LAB/6834 Thèse Bibliothèque principale Thèses Disponible
Titre : étude phytochimique et pharmacologique d'une espèce de la famille Apiaceae : Anthriscus vulgaris Bernh. Type de document : texte imprimé Auteurs : Ines Sekhara, Auteur ; Ouahiba Benaissa, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2020 Importance : 180 f. Format : 30 cm. Note générale : Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique:Analyse physicochimique, contrôle de la qualité et synthèse de substances bioactives Apaiceae anthriscus vulgaris flavonaide coumarine antioxidant antibacterienne anticholinesterase flavonoid coumarin antibacterial فلافونويد كومازين مضاد للأكسدة مضاد للجراثيم مضاد الكولينستراز Index. décimale : 540 Chimie et sciences connexes Note de contenu : Annexes.
Diplôme : Doctorat En ligne : ../theses/chimie/SEK7844.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11747 étude phytochimique et pharmacologique d'une espèce de la famille Apiaceae : Anthriscus vulgaris Bernh. [texte imprimé] / Ines Sekhara, Auteur ; Ouahiba Benaissa, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2020 . - 180 f. ; 30 cm.
Doctorat 3éme CYCLE LMD.
1 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique:Analyse physicochimique, contrôle de la qualité et synthèse de substances bioactives Apaiceae anthriscus vulgaris flavonaide coumarine antioxidant antibacterienne anticholinesterase flavonoid coumarin antibacterial فلافونويد كومازين مضاد للأكسدة مضاد للجراثيم مضاد الكولينستراز Index. décimale : 540 Chimie et sciences connexes Note de contenu : Annexes.
Diplôme : Doctorat En ligne : ../theses/chimie/SEK7844.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11747 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité SEK/7844 SEK/7844 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude phytochimique et valorisation biologique des deux plantes, Genista quadriflora Munby (Fabaceae) et Convolvulus tricolor L. (Convolvulaceae) Type de document : texte imprimé Auteurs : Nassira Kacem, Auteur ; Salah Rhouati, Directeur de thèse ; Kurt Hostettmann, Directeur de thèse Editeur : constantine [Algérie] : Université Constantine 1 Année de publication : 2015 Importance : 299 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Genista Convolvulus alcaloïdes acides caféoylquiniques sesquiterpènes flavonoïdes HPLC MPLC CPC ESIMS GC/EIMS HR-MS/TOF Q-TRAP MSn RMN-2D leishmanicide antipaludique antibactérienne antifongique antiradicalaire acétylcholinestérase alkaloids caffeoylquinic acids sesquiterpenoids flavonoids antileishmanial antimalarial antibacterial antifungal antiradical acetylcholinesterase قلويدات احماض كافيولكينية سيسكويتربنات فلافونيدات مضاد للأكسدة
الضد ميكروبية الضد فطرية مضاد للإنزيم اسيتلكولنستغاز مضاد للملاريا مضاد للشمانيا،Index. décimale : 540 Chimie et sciences connexes Résumé : This work was focused on two Algerian plants, the endemic species Genista quadriflora Munby (Fabaceae) and the species Convolvulus tricolor (Convolvulaceae). The study of the alkaloid profile of G. quadriflora by GC/EIMS allowed the identification of twenty compounds, among which ten are newly registered for the genus. We indicate the presence of:
• Thirteen quinolizidine alkaloids
• Five piperidine alkaloids
• One nicotinic alkaloid, in addition to a nicotinic acid derivative.
The investigation of the G. quadriflora essential oil has lead to the identification of 222 compounds,of which 197 are reported for the first time in the genus. This oil is mainly composed of terpenoids(66.85%) with a prevalence of sesquiterpenoids (65.18%). The major compounds are cited as:
• Salvial-4 (14) - in-1-one; germacra-4 (15), 5, 10 (14) - trien-1-α-ol; amorpha-4, 9-dien-2-
ol; muurolan-4, 7-peroxide.
Also, twenty two compounds (caffeoylquinic acids, flavonoids, coumarin, phenol acid) were isolated from C. tricolor and G. quadriflora. All these compounds are reported for the first time in the studied species. The structural determination was carried out by mass spectrometry in electronic impact EIMS, by electrospray ESIMS, by high-resolution mass spectrometry HRMS, by time of flight HR-TOFMS, and by mass spectrometry high-resolution tandem MSn. In addition, we used NMR-1D and 2D spectroscopy.
The second part of our work was an in vitro evaluation of the biological activities such as:
• antileishmanial activity, antimalarial activity, antifungal and antibacterial activities, antioxidant activity against the DPPH, and the activity towards the enzyme acetylcholinesterase.
The various tests carried out during this work have leads to tracks quite interesting especially for:
• Samples of Convolvulus tricolor with inhibitions of the parasitic activity going from 89 to 99% by quite low rates of toxicity indicating their good selective activity on the parasites.
• The alkaloids extract resulting from the air parts of Genista quadriflora for which the bacteria type Pseudomonas aeruginosa had a very particular sensitivity.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/KAC6789.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9979 Etude phytochimique et valorisation biologique des deux plantes, Genista quadriflora Munby (Fabaceae) et Convolvulus tricolor L. (Convolvulaceae) [texte imprimé] / Nassira Kacem, Auteur ; Salah Rhouati, Directeur de thèse ; Kurt Hostettmann, Directeur de thèse . - constantine [Algérie] : Université Constantine 1, 2015 . - 299 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Genista Convolvulus alcaloïdes acides caféoylquiniques sesquiterpènes flavonoïdes HPLC MPLC CPC ESIMS GC/EIMS HR-MS/TOF Q-TRAP MSn RMN-2D leishmanicide antipaludique antibactérienne antifongique antiradicalaire acétylcholinestérase alkaloids caffeoylquinic acids sesquiterpenoids flavonoids antileishmanial antimalarial antibacterial antifungal antiradical acetylcholinesterase قلويدات احماض كافيولكينية سيسكويتربنات فلافونيدات مضاد للأكسدة
الضد ميكروبية الضد فطرية مضاد للإنزيم اسيتلكولنستغاز مضاد للملاريا مضاد للشمانيا،Index. décimale : 540 Chimie et sciences connexes Résumé : This work was focused on two Algerian plants, the endemic species Genista quadriflora Munby (Fabaceae) and the species Convolvulus tricolor (Convolvulaceae). The study of the alkaloid profile of G. quadriflora by GC/EIMS allowed the identification of twenty compounds, among which ten are newly registered for the genus. We indicate the presence of:
• Thirteen quinolizidine alkaloids
• Five piperidine alkaloids
• One nicotinic alkaloid, in addition to a nicotinic acid derivative.
The investigation of the G. quadriflora essential oil has lead to the identification of 222 compounds,of which 197 are reported for the first time in the genus. This oil is mainly composed of terpenoids(66.85%) with a prevalence of sesquiterpenoids (65.18%). The major compounds are cited as:
• Salvial-4 (14) - in-1-one; germacra-4 (15), 5, 10 (14) - trien-1-α-ol; amorpha-4, 9-dien-2-
ol; muurolan-4, 7-peroxide.
Also, twenty two compounds (caffeoylquinic acids, flavonoids, coumarin, phenol acid) were isolated from C. tricolor and G. quadriflora. All these compounds are reported for the first time in the studied species. The structural determination was carried out by mass spectrometry in electronic impact EIMS, by electrospray ESIMS, by high-resolution mass spectrometry HRMS, by time of flight HR-TOFMS, and by mass spectrometry high-resolution tandem MSn. In addition, we used NMR-1D and 2D spectroscopy.
The second part of our work was an in vitro evaluation of the biological activities such as:
• antileishmanial activity, antimalarial activity, antifungal and antibacterial activities, antioxidant activity against the DPPH, and the activity towards the enzyme acetylcholinesterase.
The various tests carried out during this work have leads to tracks quite interesting especially for:
• Samples of Convolvulus tricolor with inhibitions of the parasitic activity going from 89 to 99% by quite low rates of toxicity indicating their good selective activity on the parasites.
• The alkaloids extract resulting from the air parts of Genista quadriflora for which the bacteria type Pseudomonas aeruginosa had a very particular sensitivity.
Diplôme : Doctorat en sciences En ligne : ../theses/chimie/KAC6789.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=9979 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KAC/6789 KAC/6789 Thèse Bibliothèque principale Thèses Disponible
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