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Nouvelle génération de Chélatants acides phénols méthyle phosphoriques. propriétés thermodynamiques et spectroscopiques / Salah Chafaa
Titre : Nouvelle génération de Chélatants acides phénols méthyle phosphoriques. propriétés thermodynamiques et spectroscopiques Type de document : texte imprimé Auteurs : Salah Chafaa ; Univ.Louis Pasteur, Éditeur scientifique ; Marie-José Schwing, Directeur de thèse Année de publication : 1993 Importance : 155 p. Note générale : 1 disponible à la salle de recherche Langues : Français (fre) Catégories : Français - Anglais
Chimie IndustrielleTags : Acide phosphorique Phénols Liaisons hydrogène intramoléculaires Potentiomètre Spectrophotométrie d' absorption. Index. décimale : 661 Chimie Industrielle Permalink : index.php?lvl=notice_display&id=4559 Nouvelle génération de Chélatants acides phénols méthyle phosphoriques. propriétés thermodynamiques et spectroscopiques [texte imprimé] / Salah Chafaa ; Univ.Louis Pasteur, Éditeur scientifique ; Marie-José Schwing, Directeur de thèse . - 1993 . - 155 p.
1 disponible à la salle de recherche
Langues : Français (fre)
Catégories : Français - Anglais
Chimie IndustrielleTags : Acide phosphorique Phénols Liaisons hydrogène intramoléculaires Potentiomètre Spectrophotométrie d' absorption. Index. décimale : 661 Chimie Industrielle Permalink : index.php?lvl=notice_display&id=4559 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité CHA/2482 CHA/2482 Thèse Bibliothèque principale Thèses Disponible Biological activities of Vitis vinifera leaves in cardiovascular diseases induced by hyperhomocysteinemia and on tumoral process. / Selma Ferhi
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Titre : Biological activities of Vitis vinifera leaves in cardiovascular diseases induced by hyperhomocysteinemia and on tumoral process. Type de document : texte imprimé Auteurs : Selma Ferhi, Auteur ; sakina Zerizer, Directeur de thèse Mention d'édition : 17/10/2019 Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2019 Importance : 133 f. Format : 30 cm. Note générale : 1 copies imprimées disponibles
Langues : Anglais (eng) Catégories : Français - Anglais
BiologieTags : Biologie Animale: Biological Sciences and Biotechnology Feuilles de vigne Vitis vinifera HPLC phenols Homocysteine hs-CRP GSH ASE DPPH ERP MCF-7 HepG2 HUVEC Bax/Bcl-2 Grape leaves Vitis vinifera أوراق العنب ( )Vitis viniferaفينولات اليوموسستيين، hs-CRPالجموتاثيون
المختزل GSHمستخرج المذيبات المعجل( )ASEمستقر الجذور الحرة DPPHالكترون رنين مغنطيسي ) (ERP
خلبيا سرطان الثدي ( )MCF-7خلبيا سرطان الكبد ( )HepG2الخمية البطانية من الوريد السري) (HUVEC
الجنيات .Bax/Bcl-Index. décimale : 570 Sciences de la vie. Biologie Résumé : Oxidative stress is defined as an imbalance between productions of free radicals and reactive metabolites. This imbalance leads to damage of important biomolecules and cells, with potential impact on the whole organism. There is currently arenewed interest in phytochemicals as sources of natural antioxidants. Hyperhomocysteinemia is usually defined as an elevation of plasma tHcy. It is an important risk factor for premature cardiovascular disease. As a result, homocysteine metabolism abnormalities are now receiving increasing attention because of their potential role in the pathogenesis of atherosclerosis and other diseases such as venous thrombosis. In this study, we tested in vivo the antioxidant and anti-inflammatory effect of the Grape Leaves (Vitis vinifera) Algerian Variety on the cardiovascular inflammation induced by Hyperhomocysteinemia. The phenolic compounds (Anthocyanins and non anthocyanins) is identified by using HPLC-DAD/ESI-MS, total Homocysteine (t-Hcy) was estimated by competitive solid phase chemiluminescence immunoassay, the plasma hs-CRP is measured by immunoturbidimetric method and the concentration of the GSH measured by spectrophotometric method. In addition, the aorta histology examined in order to confirm the angiotoxic action of homocysteine and the reparative effect of grape leaves (Vitis vinifera) on the aorta. Results showed high levels of phenols, anthocyanins, flavonols and trans-caftaric acid in grape leaves (Vitis vinifera). The plasma hs-CRP and homocysteine levels were elevated significantly (p < 0.05) however the glutathione reduced significantly (p < 0.05) after the administration of L-methionine in high doses to mice. This was associated with the desquamation of endothelium and muscular lysis with transformation of spindle nuclei to oval nuclei; this is due to the angiotoxic action of homocysteine on the aorta. These changes were not observed in mice treated with L-methionine plus the antioxidant and anti-inflammatory extract of grape leaves (Vitis vinifera). So, the study proved the antioxidant and anti-inflammatory effects of the grape leaves (Vitis vinifera) on hyperhomocysteinemia induced inflammatory endothelial damage in cardiovascular diseases. Moreover, in the present thesis, we conducted a study in vitro to analyze the total phenols, anti-oxidative, anti-proliferative properties on MCF-7 and HepG2 Human Cancer Cell Lines and on modulate of Apoptosis-Related Gene Expression of water and ethanol crude extracts obtained by Accelerator Solvent Extractor from grape leaves (Vitis vinifera) grown in Algeria. The results revealed for the first time that accelerator solvent extraction yielded a higher extraction rate of total phenols and antioxidant activity in an extremely short time. The extract obtained from grape leaves (Vitis vinifera) grown in the Medea region (Algeria) exhibited an antiproliferative effect on MCF-7 breast cancer cells and HepG2 hepatocarcinoma cells. Moreover, considering previous reports by other authors and the present results that provides evidence for the modulation of Bax/Bcl2 mRNA levels by leaf extracts, which affects the balance between apoptosis and cell survival, it may be concluded that these extracts could be used as an easily accessible source of natural antioxidants, and as a matrix to prepare drugs counteracting distinctive cancer cells‟ proliferation.
Note de contenu : Annexes. Diplôme : Doctorat en sciences En ligne : ../theses/biologie/FER7576.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11414 Biological activities of Vitis vinifera leaves in cardiovascular diseases induced by hyperhomocysteinemia and on tumoral process. [texte imprimé] / Selma Ferhi, Auteur ; sakina Zerizer, Directeur de thèse . - 17/10/2019 . - جامعة الإخوة منتوري قسنطينة, 2019 . - 133 f. ; 30 cm.
1 copies imprimées disponibles
Langues : Anglais (eng)
Catégories : Français - Anglais
BiologieTags : Biologie Animale: Biological Sciences and Biotechnology Feuilles de vigne Vitis vinifera HPLC phenols Homocysteine hs-CRP GSH ASE DPPH ERP MCF-7 HepG2 HUVEC Bax/Bcl-2 Grape leaves Vitis vinifera أوراق العنب ( )Vitis viniferaفينولات اليوموسستيين، hs-CRPالجموتاثيون
المختزل GSHمستخرج المذيبات المعجل( )ASEمستقر الجذور الحرة DPPHالكترون رنين مغنطيسي ) (ERP
خلبيا سرطان الثدي ( )MCF-7خلبيا سرطان الكبد ( )HepG2الخمية البطانية من الوريد السري) (HUVEC
الجنيات .Bax/Bcl-Index. décimale : 570 Sciences de la vie. Biologie Résumé : Oxidative stress is defined as an imbalance between productions of free radicals and reactive metabolites. This imbalance leads to damage of important biomolecules and cells, with potential impact on the whole organism. There is currently arenewed interest in phytochemicals as sources of natural antioxidants. Hyperhomocysteinemia is usually defined as an elevation of plasma tHcy. It is an important risk factor for premature cardiovascular disease. As a result, homocysteine metabolism abnormalities are now receiving increasing attention because of their potential role in the pathogenesis of atherosclerosis and other diseases such as venous thrombosis. In this study, we tested in vivo the antioxidant and anti-inflammatory effect of the Grape Leaves (Vitis vinifera) Algerian Variety on the cardiovascular inflammation induced by Hyperhomocysteinemia. The phenolic compounds (Anthocyanins and non anthocyanins) is identified by using HPLC-DAD/ESI-MS, total Homocysteine (t-Hcy) was estimated by competitive solid phase chemiluminescence immunoassay, the plasma hs-CRP is measured by immunoturbidimetric method and the concentration of the GSH measured by spectrophotometric method. In addition, the aorta histology examined in order to confirm the angiotoxic action of homocysteine and the reparative effect of grape leaves (Vitis vinifera) on the aorta. Results showed high levels of phenols, anthocyanins, flavonols and trans-caftaric acid in grape leaves (Vitis vinifera). The plasma hs-CRP and homocysteine levels were elevated significantly (p < 0.05) however the glutathione reduced significantly (p < 0.05) after the administration of L-methionine in high doses to mice. This was associated with the desquamation of endothelium and muscular lysis with transformation of spindle nuclei to oval nuclei; this is due to the angiotoxic action of homocysteine on the aorta. These changes were not observed in mice treated with L-methionine plus the antioxidant and anti-inflammatory extract of grape leaves (Vitis vinifera). So, the study proved the antioxidant and anti-inflammatory effects of the grape leaves (Vitis vinifera) on hyperhomocysteinemia induced inflammatory endothelial damage in cardiovascular diseases. Moreover, in the present thesis, we conducted a study in vitro to analyze the total phenols, anti-oxidative, anti-proliferative properties on MCF-7 and HepG2 Human Cancer Cell Lines and on modulate of Apoptosis-Related Gene Expression of water and ethanol crude extracts obtained by Accelerator Solvent Extractor from grape leaves (Vitis vinifera) grown in Algeria. The results revealed for the first time that accelerator solvent extraction yielded a higher extraction rate of total phenols and antioxidant activity in an extremely short time. The extract obtained from grape leaves (Vitis vinifera) grown in the Medea region (Algeria) exhibited an antiproliferative effect on MCF-7 breast cancer cells and HepG2 hepatocarcinoma cells. Moreover, considering previous reports by other authors and the present results that provides evidence for the modulation of Bax/Bcl2 mRNA levels by leaf extracts, which affects the balance between apoptosis and cell survival, it may be concluded that these extracts could be used as an easily accessible source of natural antioxidants, and as a matrix to prepare drugs counteracting distinctive cancer cells‟ proliferation.
Note de contenu : Annexes. Diplôme : Doctorat en sciences En ligne : ../theses/biologie/FER7576.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=11414 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité FER/7576 FER/7576 Thèse Bibliothèque principale Thèses Disponible دراسة فيتوكيميائية لنباتات Euphorbia clementei Boiss. (Euphorbiaceae) Eryngium tricuspidatum L. (Apiaceae) Cladanthus mixtus (L.) Oberpr. & Vogt (Asteraceae) / عباس بن مرعاش
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Titre : دراسة فيتوكيميائية لنباتات Euphorbia clementei Boiss. (Euphorbiaceae) Eryngium tricuspidatum L. (Apiaceae) Cladanthus mixtus (L.) Oberpr. & Vogt (Asteraceae) Type de document : texte imprimé Auteurs : عباس بن مرعاش, Auteur ; أحمد كعبوش, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 342 ورقة. Format : 30 سم. Note générale : 2نسخ موجودة مكتبة المركزية
Langues : Arabe (ara) Catégories : Arabe
الكيمياء و العلوم ذات العلاقةTags : Euphorbia clementei Eryngium tricuspidatum Cladanthus mixtus terpenes flavonoids phenols quinic acid Cladanthus mixtus Terpènes acides phenolques acides quiniques تريبنات فلافونيدات احماض فينولية فينول غليكوزيدي مشتقات حمض الكينيك Index. décimale : 540 الكيمياء و العلوم ذات العلاقة Résumé : From the photochemical study of 3 Algerian plants Euphorbia clementei (Euphorbiaceae), Eryngium tricuspidatum (Apiaceae), Cladanthus mixtus (Asteraceae), 42 compounds from which 3 are new, have been isolated and identified by the use of chromatographic techniques of separation and purification (CC, TLC, HPLC and EPC) and by spectral techniques e.g UV, NMR 1D and 2D, MS HRESI. The latex and CHCL3 extracts of E. clementei led to the isolation of 7 compounds, one new diterpenoid, 2 monoterpenes and 4 triterpenes. 8 Compounds (3 phenols glycosyls from which two are new, 2 monoterpenes, 1 coumarin and 2 flavonoids) have been isolated from the methanol extract of E. tricuspidatum.
The phytochemical investigation of ethyl the acetate and n_butanol extracts of C. mixtus allowed the isolation and identification of 27 compounds from which 15 flavonoids, 5 phenolic acids, 5 quinic acids, 1 phenol glycoside and 1 monoterpene glycoside.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/ABEN4203.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10671 دراسة فيتوكيميائية لنباتات Euphorbia clementei Boiss. (Euphorbiaceae) Eryngium tricuspidatum L. (Apiaceae) Cladanthus mixtus (L.) Oberpr. & Vogt (Asteraceae) [texte imprimé] / عباس بن مرعاش, Auteur ; أحمد كعبوش, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2017 . - 342 ورقة. ; 30 سم.
2نسخ موجودة مكتبة المركزية
Langues : Arabe (ara)
Catégories : Arabe
الكيمياء و العلوم ذات العلاقةTags : Euphorbia clementei Eryngium tricuspidatum Cladanthus mixtus terpenes flavonoids phenols quinic acid Cladanthus mixtus Terpènes acides phenolques acides quiniques تريبنات فلافونيدات احماض فينولية فينول غليكوزيدي مشتقات حمض الكينيك Index. décimale : 540 الكيمياء و العلوم ذات العلاقة Résumé : From the photochemical study of 3 Algerian plants Euphorbia clementei (Euphorbiaceae), Eryngium tricuspidatum (Apiaceae), Cladanthus mixtus (Asteraceae), 42 compounds from which 3 are new, have been isolated and identified by the use of chromatographic techniques of separation and purification (CC, TLC, HPLC and EPC) and by spectral techniques e.g UV, NMR 1D and 2D, MS HRESI. The latex and CHCL3 extracts of E. clementei led to the isolation of 7 compounds, one new diterpenoid, 2 monoterpenes and 4 triterpenes. 8 Compounds (3 phenols glycosyls from which two are new, 2 monoterpenes, 1 coumarin and 2 flavonoids) have been isolated from the methanol extract of E. tricuspidatum.
The phytochemical investigation of ethyl the acetate and n_butanol extracts of C. mixtus allowed the isolation and identification of 27 compounds from which 15 flavonoids, 5 phenolic acids, 5 quinic acids, 1 phenol glycoside and 1 monoterpene glycoside.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/ABEN4203.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10671 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité بنم/4203 بنم/4203 Thèse Bibliothèque principale Thèses Disponible Caractérisation de l’arganier (Argania spinosa L.) en Algérie et impact de la salinité / Mohamed Seif Allah Kechebar
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Titre : Caractérisation de l’arganier (Argania spinosa L.) en Algérie et impact de la salinité Type de document : texte imprimé Auteurs : Mohamed Seif Allah Kechebar, Auteur ; Chaabane Rahmoune, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 209 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Argania spinosa Tindouf cartographie structure huile d’argan phénols mapping argan oil phenols شجرة الأركان:تندوف علم الخرائط بنية زيت الأركان فينول Index. décimale : 570 Sciences de la vie. Biologie Résumé : Through this work, we mapped the range of the argan tree in Algeria, studied stand structure, characterized argan oil and assess the impact of soil salinity on secondary metabolites (phenolic compounds). The main results showed that the argan tree covers an area of 96940 ha spread over two main perimeters where the altitude ranging from 315 to 630 m.
Stands are widely dispersed with an average height of 3 to 6 m and a surface crown between
24 and 68m2. Argan oil is a fine virgin oil, rich in linoleic acid (35%) and β-sitosterol (64%), characterized by low chlorophyll content (1.3 mg Pheophytin / kg oil) and low specific
extinction coefficient (K232 = 1.15). Results also showed that the argan tree can support very
salty soils (4.35 to 8.5 millimhos / cm) with an important accumulation of phenolic compounds (77.28 mg GAE g-1MS) as an adaptive response to salt stress. Qualitative analysis by LC-ESI-MS of phenolic compounds found that certain molecules appear under the effect of salt and other disappears when salinity becomes extreme. The study of antioxidant activities confirmed all these results and we have noted the best activities for the plant extracts from very salty soil. The present work has provided scientific information about the argan which inciting to preserve, develop and promote it in a vision of sustainable development.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/KEC6896.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10225 Caractérisation de l’arganier (Argania spinosa L.) en Algérie et impact de la salinité [texte imprimé] / Mohamed Seif Allah Kechebar, Auteur ; Chaabane Rahmoune, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 209 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Argania spinosa Tindouf cartographie structure huile d’argan phénols mapping argan oil phenols شجرة الأركان:تندوف علم الخرائط بنية زيت الأركان فينول Index. décimale : 570 Sciences de la vie. Biologie Résumé : Through this work, we mapped the range of the argan tree in Algeria, studied stand structure, characterized argan oil and assess the impact of soil salinity on secondary metabolites (phenolic compounds). The main results showed that the argan tree covers an area of 96940 ha spread over two main perimeters where the altitude ranging from 315 to 630 m.
Stands are widely dispersed with an average height of 3 to 6 m and a surface crown between
24 and 68m2. Argan oil is a fine virgin oil, rich in linoleic acid (35%) and β-sitosterol (64%), characterized by low chlorophyll content (1.3 mg Pheophytin / kg oil) and low specific
extinction coefficient (K232 = 1.15). Results also showed that the argan tree can support very
salty soils (4.35 to 8.5 millimhos / cm) with an important accumulation of phenolic compounds (77.28 mg GAE g-1MS) as an adaptive response to salt stress. Qualitative analysis by LC-ESI-MS of phenolic compounds found that certain molecules appear under the effect of salt and other disappears when salinity becomes extreme. The study of antioxidant activities confirmed all these results and we have noted the best activities for the plant extracts from very salty soil. The present work has provided scientific information about the argan which inciting to preserve, develop and promote it in a vision of sustainable development.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/KEC6896.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10225 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEC/6896 KEC/6896 Thèse Bibliothèque principale Thèses Disponible Etude écophysiologique, développement et importance des plantes médicinales du genre Mentha dans le Parc National d’El-Kala (Nord-Est Algérie). / Amina Benabdallah
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Titre : Etude écophysiologique, développement et importance des plantes médicinales du genre Mentha dans le Parc National d’El-Kala (Nord-Est Algérie). Type de document : texte imprimé Auteurs : Amina Benabdallah, Auteur ; Chaabane Rahmoune, Directeur de thèse Importance : 152 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : M. aquatica M. arvensis Mx piperita M.pulegium M. rotundifolia M. x villosa NPEK ElKala RAMSAR phenols flavonoids tannins essential oil antioxidant acetylcholinesterase PNEK phénols, flavonoïdes, huile essentielle antioxydant acétylcholinestérase Index. décimale : 570 Sciences de la vie. Biologie Résumé : Mentha species are widely used by native habitants of El-Tarf region, as condiment, flavor or
herb in culinary preparations but also used for therapeutic properties as carminative, sedative,
antispasmodic and well known to treat stomach pain.
The aim of this work was first to inventory and geolocalisate Mentha species of the National
Park of El-Kala and then to investigate the total phenolics, flavonoids and tannins content and
the in-vitro antioxidant activities of methanolic extracts and essential oils, then to evaluate the
chemical composition of essential oils obtained from aerial parts of six wildMentha species:
M. aquatica, M. arvensis, M x piperita, M. pulegium, M. rotundifolia and M x villosa.
Chemical composition was analyzed by GC-MS method and biological activities investigated
by DPPH, B-carotene bleaching and ion chelating assays for the antioxidant activity, as well
as the inhibition of acetycholinesterase. The methanol extracts of mints were rich in phenolic
compounds and exhibited a powerful antioxidant activity ranged from7.5µg/mlto44.66
µg/ml,which varied significantly among species. M. aquatica stands out with an efficient
antioxidant ability which is correlated to the high total phenolics contents, followed by M.
arvensis and M. piperita with very close values, comparing to M. pulegium, M. rotundifolia
and M. villosa with lowest values. Qualitative and quantitative variations were observed
among species. The highest yield of oils, obtained by hydrodistillation, was recorded for M.
pulegium with 1.8%. A total of 27 compounds were identified with the predominance of
oxygenated monoterpenes such as menthofurane (73.38%), rotundifolone (65.99%), pulegone
(59.12%), menthol (49.89%), menthone (20.84%), neomenthol (20.76%), 1.8-cineol (18.16%)
and β-caryophyllene (12.55%). In general, M. aquatica exhibited the strongest antioxidant
level with IC50 of 0.69±0.06 mg/ml assessed by DPPH assay, 0.16±0.02 mg/ml by β-Carotene
bleaching and 1.73±0.17 mg/ml by ferrous ion chelating method. Whereas M. arvensisstood
out with IC50 of 27.5mg/ml for acetylcholinesterase inhibitory.These results show that Mentha
species from NPEK have a great potential of polyphenols which can be used as a natural food
preservative and antioxidant source. Moreover, mints could be exploited for their
pharmacological application in order to prevent induced diseases relied to oxidative stress.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BEN7087.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10514 Etude écophysiologique, développement et importance des plantes médicinales du genre Mentha dans le Parc National d’El-Kala (Nord-Est Algérie). [texte imprimé] / Amina Benabdallah, Auteur ; Chaabane Rahmoune, Directeur de thèse . - [s.d.] . - 152 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : M. aquatica M. arvensis Mx piperita M.pulegium M. rotundifolia M. x villosa NPEK ElKala RAMSAR phenols flavonoids tannins essential oil antioxidant acetylcholinesterase PNEK phénols, flavonoïdes, huile essentielle antioxydant acétylcholinestérase Index. décimale : 570 Sciences de la vie. Biologie Résumé : Mentha species are widely used by native habitants of El-Tarf region, as condiment, flavor or
herb in culinary preparations but also used for therapeutic properties as carminative, sedative,
antispasmodic and well known to treat stomach pain.
The aim of this work was first to inventory and geolocalisate Mentha species of the National
Park of El-Kala and then to investigate the total phenolics, flavonoids and tannins content and
the in-vitro antioxidant activities of methanolic extracts and essential oils, then to evaluate the
chemical composition of essential oils obtained from aerial parts of six wildMentha species:
M. aquatica, M. arvensis, M x piperita, M. pulegium, M. rotundifolia and M x villosa.
Chemical composition was analyzed by GC-MS method and biological activities investigated
by DPPH, B-carotene bleaching and ion chelating assays for the antioxidant activity, as well
as the inhibition of acetycholinesterase. The methanol extracts of mints were rich in phenolic
compounds and exhibited a powerful antioxidant activity ranged from7.5µg/mlto44.66
µg/ml,which varied significantly among species. M. aquatica stands out with an efficient
antioxidant ability which is correlated to the high total phenolics contents, followed by M.
arvensis and M. piperita with very close values, comparing to M. pulegium, M. rotundifolia
and M. villosa with lowest values. Qualitative and quantitative variations were observed
among species. The highest yield of oils, obtained by hydrodistillation, was recorded for M.
pulegium with 1.8%. A total of 27 compounds were identified with the predominance of
oxygenated monoterpenes such as menthofurane (73.38%), rotundifolone (65.99%), pulegone
(59.12%), menthol (49.89%), menthone (20.84%), neomenthol (20.76%), 1.8-cineol (18.16%)
and β-caryophyllene (12.55%). In general, M. aquatica exhibited the strongest antioxidant
level with IC50 of 0.69±0.06 mg/ml assessed by DPPH assay, 0.16±0.02 mg/ml by β-Carotene
bleaching and 1.73±0.17 mg/ml by ferrous ion chelating method. Whereas M. arvensisstood
out with IC50 of 27.5mg/ml for acetylcholinesterase inhibitory.These results show that Mentha
species from NPEK have a great potential of polyphenols which can be used as a natural food
preservative and antioxidant source. Moreover, mints could be exploited for their
pharmacological application in order to prevent induced diseases relied to oxidative stress.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BEN7087.pdf Format de la ressource électronique : Permalink : index.php?lvl=notice_display&id=10514 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEN/7087 BEN/7087 Thèse Bibliothèque principale Thèses Disponible تقييم الأثر الوقائي و/أو التعديلي للمنتجات الطبيعية النشطة بيولوجيا اثر الإصابة النفرونية المحرضة بالزئبق in vivo و in vitro / نادية دكدوك
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