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Partager le résultat de cette recherche Interroger des sources externesÉlaboration de nouvelles voies catalytiques dans la synthese de molécules hétérocycliques / Faiza Boukezzoula
Titre : Élaboration de nouvelles voies catalytiques dans la synthese de molécules hétérocycliques Type de document : texte imprimé Auteurs : Faiza Boukezzoula, Auteur ; Taoues Boumoud, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 196 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : hétérocycles synthèse convergente réactions à composants multiples catalyse
organique molécules chirales et achirales synthèse asymétrique liquides ioniques pyrazolopyranopyrimidines pyranopyrazoles spirooxindoles heterocyclic compounds convergent strategy MCRs Organocatalysis asymmetrical and symmetrical molecules asymmetric synthesis ionic liquids ???????? ??????? ????? ??????? ????????? ????????? ???????? ?????????? ???????? ??????? ???????? ????????? ?????????? ??????? ???????? ??????????????????????? ????????????? ?????? ???????Index. décimale : 540 Chimie et sciences connexes Résumé : The subject that we developed "Elaboration of novel catalytic methods for the synthesis of
heterocyclic molecules " summarizes:
- Through a bibliographical study which puts forward the heterocyclic compounds, the advantage of the reactions making their synthesis possible, in occurrence MCRs and the privilege of organic catalysis.
- Through a study of the catalytic properties of two molecules asymmetrical (DMAP and DABCO) and two symmetrical (L-Proline and Cinchonine) with respect to the synthesis of
pyrazolpyrnopyrimidindiones/ones and pyranopyrazoles, via multicomponent reactions
- Through a study of catalytic properties of two ionic liquids [MePPh3][Br] and [OPPh3][Br] in the synthesis of the spirooxindoles and the pyranopyrazoles. The results with [OPPh3][Br] are not as good as those obtained with [MePPh3][Br], which certainly due to its cumbersome properties.
- This study reinforced the idea of the organic catalysis in MCRs giving the
pyrazolopyranopyrimidindiones/ones the pyranopyrazoles and the spirooxindoles
heterocyclic compoundsDiplôme : Doctorat En ligne : ../theses/chimie/BOU6898.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10228 Élaboration de nouvelles voies catalytiques dans la synthese de molécules hétérocycliques [texte imprimé] / Faiza Boukezzoula, Auteur ; Taoues Boumoud, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2016 . - 196 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : hétérocycles synthèse convergente réactions à composants multiples catalyse
organique molécules chirales et achirales synthèse asymétrique liquides ioniques pyrazolopyranopyrimidines pyranopyrazoles spirooxindoles heterocyclic compounds convergent strategy MCRs Organocatalysis asymmetrical and symmetrical molecules asymmetric synthesis ionic liquids ???????? ??????? ????? ??????? ????????? ????????? ???????? ?????????? ???????? ??????? ???????? ????????? ?????????? ??????? ???????? ??????????????????????? ????????????? ?????? ???????Index. décimale : 540 Chimie et sciences connexes Résumé : The subject that we developed "Elaboration of novel catalytic methods for the synthesis of
heterocyclic molecules " summarizes:
- Through a bibliographical study which puts forward the heterocyclic compounds, the advantage of the reactions making their synthesis possible, in occurrence MCRs and the privilege of organic catalysis.
- Through a study of the catalytic properties of two molecules asymmetrical (DMAP and DABCO) and two symmetrical (L-Proline and Cinchonine) with respect to the synthesis of
pyrazolpyrnopyrimidindiones/ones and pyranopyrazoles, via multicomponent reactions
- Through a study of catalytic properties of two ionic liquids [MePPh3][Br] and [OPPh3][Br] in the synthesis of the spirooxindoles and the pyranopyrazoles. The results with [OPPh3][Br] are not as good as those obtained with [MePPh3][Br], which certainly due to its cumbersome properties.
- This study reinforced the idea of the organic catalysis in MCRs giving the
pyrazolopyranopyrimidindiones/ones the pyranopyrazoles and the spirooxindoles
heterocyclic compoundsDiplôme : Doctorat En ligne : ../theses/chimie/BOU6898.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10228 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BOU/6898 BOU/6898 Thèse Bibliothèque principale Thèses Disponible
Titre : Synthèse et caractérisation de poly-hétérocycles bioactifs Type de document : texte imprimé Auteurs : Chamseddine Derabli, Auteur ; Raouf Boulcina, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 217 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Quinolones cyclisation d’aza-Michael liquides ioniques quinazolines quinazolinones quinoléines pyranopyrazoles pyrimidines Tacrine Maladie d’Alzheimer aza-Michael cyclization ionic liquids quinolines Alzheimer's disease ??????????? ???? ???-??????? ?????? ??????? ????????????? ??????? ????????? ?????? ???
??????????Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript includes three main parts:
In the first chapter, we described a new method for preparation of 2-aryl-2,3-dihydro-4-quinolonesby the use of the cyclization of the corresponding 2-aminochalconesvia an azaMichael reaction. This method was catalyzed by a DABCO’s ionic liquid which allowed us to obtain quantitatively our intended products in a single step.
In the second chapter, we synthesized a series of new 1,2-dihydroquinazoline derivatives by a one pot reaction, from benzaldehyde derivatives, ammonium acetate and 2-aminobenzophenones in the presence of DMAP. Similarly, we described the synthesis of new hybrid quinazoline-quinoline compounds from raw materials and other easily accessible key intermediates.
Finally, the study that we have undertaken in this final chapter of the thesis has as main objective, the preparation of novel heterocyclic analogues of Tacrine (used in the treatment of Alzheimer's disease) based pyranopyrazole and pyrimidine structures.
Diplôme : Doctorat Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10221 Synthèse et caractérisation de poly-hétérocycles bioactifs [texte imprimé] / Chamseddine Derabli, Auteur ; Raouf Boulcina, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2016 . - 217 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Quinolones cyclisation d’aza-Michael liquides ioniques quinazolines quinazolinones quinoléines pyranopyrazoles pyrimidines Tacrine Maladie d’Alzheimer aza-Michael cyclization ionic liquids quinolines Alzheimer's disease ??????????? ???? ???-??????? ?????? ??????? ????????????? ??????? ????????? ?????? ???
??????????Index. décimale : 540 Chimie et sciences connexes Résumé : This manuscript includes three main parts:
In the first chapter, we described a new method for preparation of 2-aryl-2,3-dihydro-4-quinolonesby the use of the cyclization of the corresponding 2-aminochalconesvia an azaMichael reaction. This method was catalyzed by a DABCO’s ionic liquid which allowed us to obtain quantitatively our intended products in a single step.
In the second chapter, we synthesized a series of new 1,2-dihydroquinazoline derivatives by a one pot reaction, from benzaldehyde derivatives, ammonium acetate and 2-aminobenzophenones in the presence of DMAP. Similarly, we described the synthesis of new hybrid quinazoline-quinoline compounds from raw materials and other easily accessible key intermediates.
Finally, the study that we have undertaken in this final chapter of the thesis has as main objective, the preparation of novel heterocyclic analogues of Tacrine (used in the treatment of Alzheimer's disease) based pyranopyrazole and pyrimidine structures.
Diplôme : Doctorat Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10221 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité DER/6892 DER/6892 Thèse Bibliothèque principale Thèses Disponible
