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Partager le résultat de cette recherche Interroger des sources externesCaractérisation de l’arganier (Argania spinosa L.) en Algérie et impact de la salinité / Mohamed Seif Allah Kechebar
Titre : Caractérisation de l’arganier (Argania spinosa L.) en Algérie et impact de la salinité Type de document : texte imprimé Auteurs : Mohamed Seif Allah Kechebar, Auteur ; Chaabane Rahmoune, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 209 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Argania spinosa Tindouf cartographie structure huile d’argan phénols mapping argan oil phenols شجرة الأركان:تندوف علم الخرائط بنية زيت الأركان فينول Index. décimale : 570 Sciences de la vie. Biologie Résumé : Through this work, we mapped the range of the argan tree in Algeria, studied stand structure, characterized argan oil and assess the impact of soil salinity on secondary metabolites (phenolic compounds). The main results showed that the argan tree covers an area of 96940 ha spread over two main perimeters where the altitude ranging from 315 to 630 m.
Stands are widely dispersed with an average height of 3 to 6 m and a surface crown between
24 and 68m2. Argan oil is a fine virgin oil, rich in linoleic acid (35%) and β-sitosterol (64%), characterized by low chlorophyll content (1.3 mg Pheophytin / kg oil) and low specific
extinction coefficient (K232 = 1.15). Results also showed that the argan tree can support very
salty soils (4.35 to 8.5 millimhos / cm) with an important accumulation of phenolic compounds (77.28 mg GAE g-1MS) as an adaptive response to salt stress. Qualitative analysis by LC-ESI-MS of phenolic compounds found that certain molecules appear under the effect of salt and other disappears when salinity becomes extreme. The study of antioxidant activities confirmed all these results and we have noted the best activities for the plant extracts from very salty soil. The present work has provided scientific information about the argan which inciting to preserve, develop and promote it in a vision of sustainable development.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/KEC6896.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10225 Caractérisation de l’arganier (Argania spinosa L.) en Algérie et impact de la salinité [texte imprimé] / Mohamed Seif Allah Kechebar, Auteur ; Chaabane Rahmoune, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 209 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Argania spinosa Tindouf cartographie structure huile d’argan phénols mapping argan oil phenols شجرة الأركان:تندوف علم الخرائط بنية زيت الأركان فينول Index. décimale : 570 Sciences de la vie. Biologie Résumé : Through this work, we mapped the range of the argan tree in Algeria, studied stand structure, characterized argan oil and assess the impact of soil salinity on secondary metabolites (phenolic compounds). The main results showed that the argan tree covers an area of 96940 ha spread over two main perimeters where the altitude ranging from 315 to 630 m.
Stands are widely dispersed with an average height of 3 to 6 m and a surface crown between
24 and 68m2. Argan oil is a fine virgin oil, rich in linoleic acid (35%) and β-sitosterol (64%), characterized by low chlorophyll content (1.3 mg Pheophytin / kg oil) and low specific
extinction coefficient (K232 = 1.15). Results also showed that the argan tree can support very
salty soils (4.35 to 8.5 millimhos / cm) with an important accumulation of phenolic compounds (77.28 mg GAE g-1MS) as an adaptive response to salt stress. Qualitative analysis by LC-ESI-MS of phenolic compounds found that certain molecules appear under the effect of salt and other disappears when salinity becomes extreme. The study of antioxidant activities confirmed all these results and we have noted the best activities for the plant extracts from very salty soil. The present work has provided scientific information about the argan which inciting to preserve, develop and promote it in a vision of sustainable development.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/KEC6896.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10225 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité KEC/6896 KEC/6896 Thèse Bibliothèque principale Thèses Disponible
Titre : The effect of Argania spinosa on plasma Homocysteine, Lipids, Antioxidant enzymes and Aortas Sections in Methionine induced Hyperhomocysteinemia in mice Type de document : texte imprimé Auteurs : Badiaa Aklil, Auteur ; Z. Kabouche, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 150 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Homocystéine Argania spinosa Antioxydant Méthionine Stress oxydant Maladies ardiovasculaires Biofilm Homocysteine Antioxidant enzymes Methionine Oxidative
stress Cardiovascular diseases الهوموسيستيين Argania spinosaالإنزيمات المضادة للأكسدة ميثيونين الإجهاد التأكسدي أمراض القلب والأوعية الدموية البيوفيلمIndex. décimale : 570 Sciences de la vie. Biologie Résumé : Hyperhomocysteinemia (HHcy), oxidative stress and decreased antioxidant capacities lead to several clinical manifestations and particularly, cardiovascular and liver diseases. In this study, we evaluated the protective and the preventive effect of the crude extract of Argania spinosa against HHcy ,hyperlipidemia, oxidant status and damages in the aorta, heart and liver induced by high L-methionine intake in mice. After 3 weeks of treatments, Hcy concentrations, lipid parameters, liver enzyme activities, hepatic antioxidant status and histological sections of aorta, liver and heart were determined. Our results showed that consumption of high L-methionine diet (500mg/Kg)
led to an increase in plasma Hcy, CHO, LDL-c, TG, AST, corresponding with decrease of HDL-c, reduced GSH, and catalase activity. These were associated with the loss and degeneration of endothelium, fenestration and formation of foam cells in the media of the aorta, also the alteration of the cardiac muscle and liver tissue. However, the administration of the crude extract of A. spinosa (150mg/Kg) in combination with L-methionine ameliorated all these changes.
Moreover, in the present thesis, we conducted a study in vitro to evaluate the antibacterial effect of Argan oil on biofilm formation. The results showed that there was a trend of increasing inhibition of 4 species of bacteria (Streptococcus mutans, Streptococcus anginosus, Streptococcus intermedius, and staphylococcus haemolyticus), that belong to gram positive strain as the Argan oil was getting more concentrated.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/AKL7340.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10990 The effect of Argania spinosa on plasma Homocysteine, Lipids, Antioxidant enzymes and Aortas Sections in Methionine induced Hyperhomocysteinemia in mice [texte imprimé] / Badiaa Aklil, Auteur ; Z. Kabouche, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2018 . - 150 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Homocystéine Argania spinosa Antioxydant Méthionine Stress oxydant Maladies ardiovasculaires Biofilm Homocysteine Antioxidant enzymes Methionine Oxidative
stress Cardiovascular diseases الهوموسيستيين Argania spinosaالإنزيمات المضادة للأكسدة ميثيونين الإجهاد التأكسدي أمراض القلب والأوعية الدموية البيوفيلمIndex. décimale : 570 Sciences de la vie. Biologie Résumé : Hyperhomocysteinemia (HHcy), oxidative stress and decreased antioxidant capacities lead to several clinical manifestations and particularly, cardiovascular and liver diseases. In this study, we evaluated the protective and the preventive effect of the crude extract of Argania spinosa against HHcy ,hyperlipidemia, oxidant status and damages in the aorta, heart and liver induced by high L-methionine intake in mice. After 3 weeks of treatments, Hcy concentrations, lipid parameters, liver enzyme activities, hepatic antioxidant status and histological sections of aorta, liver and heart were determined. Our results showed that consumption of high L-methionine diet (500mg/Kg)
led to an increase in plasma Hcy, CHO, LDL-c, TG, AST, corresponding with decrease of HDL-c, reduced GSH, and catalase activity. These were associated with the loss and degeneration of endothelium, fenestration and formation of foam cells in the media of the aorta, also the alteration of the cardiac muscle and liver tissue. However, the administration of the crude extract of A. spinosa (150mg/Kg) in combination with L-methionine ameliorated all these changes.
Moreover, in the present thesis, we conducted a study in vitro to evaluate the antibacterial effect of Argan oil on biofilm formation. The results showed that there was a trend of increasing inhibition of 4 species of bacteria (Streptococcus mutans, Streptococcus anginosus, Streptococcus intermedius, and staphylococcus haemolyticus), that belong to gram positive strain as the Argan oil was getting more concentrated.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/AKL7340.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10990 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité AKL/7340 AKL/7340 Thèse Bibliothèque principale Thèses Disponible
Titre : L’effet protecteur des antioxydants naturels dans l’intoxication du mercure chez le rat Albinos Wistar : (Aspects biochimiques, immunologiques et histologiques). Type de document : texte imprimé Auteurs : Ahlem Bahi, Auteur ; Youcef Necib, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 158 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Biochimie appliquee Mercure Huile d’argan Sélénium Stress oxydatif Argania Spinosa antioxydants Mercury Argan Oil Selenium Oxidative Stress antioxidants السلينيوم الإجهاد التاكسدي زيت الأركان الزئبق Index. décimale : 570 Sciences de la vie. Biologie Résumé : The present study aimed to evaluate the protective effect of argan oil and selenium against oxidative stress induced by mercury. For this reason, a phytochemical study of antioxidant tested in vitro was performed on argan oil to estimate its expected effect. The results showed the presence of phenolic compounds in a very high concentration. The evaluation of power scavenger argan oil is more active with IC50 = 13.33 ± 1.3, and in vivo on Albino Wistar rats were treated with mercury alone or combined with argan oil and selenium, for a period of three weeks, the blood is then withdrawn and the rats are sacrificed the various parameters are determined. From the analysis of our results, we observed a significant reduction in weight gain during treatment with mercury alone or combined with argan oil and selenium, but no clear change in the relative weight of liver, kidney or spleen was obtained. The results also showed significant changes in biochemical parameters, immunological and haematological. Characterized primarily by a significant increase in serum glucose, urea, creatinine, uric acid, total and direct bilirubin, total lipids, cholesterol, triglyceride, conjugated diene and the enzymatic activity of AST, ALT, LDH and PAL .dropoff window Whereas serum concentrations of albumin and total protein were reduced in treated rats compared to mercury control animals. Results also show immunological and haematological toxicity especially among the treated groups the pure mercury, an increase in serum IL-1, IL-6 and TNF and elevated white blood cell count, decreased red blood cell levels, hemoglobin concentration the percentage of hematocrit and phagocytic activity during treatment with mercury. Thus the treatment of the rats with the mercury causes a reduction in the plasma antioxidant capacity characterized by decrease in the serum concentration of vitamin E and C and rate of DPPH and thiols. We also observed that the results obtained highlight the detoxifier potential expressed by the decrease in erythrocyte glutathione levels, liver and kidney, metallothionein, the enzymatic activity of the antioxidant system SOD, GPx, GST and catalase and increased in lipid peroxidation expressed by the high levels of plasma MDA, erythrocyte, liver and kidney. Also the results clearly showed substantive alterations of tissue studies in comparison with the control, with hepatocyte cytolysis, hepatic necrosis and tubular degeneration with necrosis of the kidneys. Furthermore supplementation argan oil and selenium changed the toxic effects of mercury and decreased histological alterations and showed that both antioxidants are effective against oxidative stress induced by mercury
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BAH6696.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9928 L’effet protecteur des antioxydants naturels dans l’intoxication du mercure chez le rat Albinos Wistar : (Aspects biochimiques, immunologiques et histologiques). [texte imprimé] / Ahlem Bahi, Auteur ; Youcef Necib, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2015 . - 158 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Biochimie appliquee Mercure Huile d’argan Sélénium Stress oxydatif Argania Spinosa antioxydants Mercury Argan Oil Selenium Oxidative Stress antioxidants السلينيوم الإجهاد التاكسدي زيت الأركان الزئبق Index. décimale : 570 Sciences de la vie. Biologie Résumé : The present study aimed to evaluate the protective effect of argan oil and selenium against oxidative stress induced by mercury. For this reason, a phytochemical study of antioxidant tested in vitro was performed on argan oil to estimate its expected effect. The results showed the presence of phenolic compounds in a very high concentration. The evaluation of power scavenger argan oil is more active with IC50 = 13.33 ± 1.3, and in vivo on Albino Wistar rats were treated with mercury alone or combined with argan oil and selenium, for a period of three weeks, the blood is then withdrawn and the rats are sacrificed the various parameters are determined. From the analysis of our results, we observed a significant reduction in weight gain during treatment with mercury alone or combined with argan oil and selenium, but no clear change in the relative weight of liver, kidney or spleen was obtained. The results also showed significant changes in biochemical parameters, immunological and haematological. Characterized primarily by a significant increase in serum glucose, urea, creatinine, uric acid, total and direct bilirubin, total lipids, cholesterol, triglyceride, conjugated diene and the enzymatic activity of AST, ALT, LDH and PAL .dropoff window Whereas serum concentrations of albumin and total protein were reduced in treated rats compared to mercury control animals. Results also show immunological and haematological toxicity especially among the treated groups the pure mercury, an increase in serum IL-1, IL-6 and TNF and elevated white blood cell count, decreased red blood cell levels, hemoglobin concentration the percentage of hematocrit and phagocytic activity during treatment with mercury. Thus the treatment of the rats with the mercury causes a reduction in the plasma antioxidant capacity characterized by decrease in the serum concentration of vitamin E and C and rate of DPPH and thiols. We also observed that the results obtained highlight the detoxifier potential expressed by the decrease in erythrocyte glutathione levels, liver and kidney, metallothionein, the enzymatic activity of the antioxidant system SOD, GPx, GST and catalase and increased in lipid peroxidation expressed by the high levels of plasma MDA, erythrocyte, liver and kidney. Also the results clearly showed substantive alterations of tissue studies in comparison with the control, with hepatocyte cytolysis, hepatic necrosis and tubular degeneration with necrosis of the kidneys. Furthermore supplementation argan oil and selenium changed the toxic effects of mercury and decreased histological alterations and showed that both antioxidants are effective against oxidative stress induced by mercury
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BAH6696.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=9928 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BAH/6696 BAH/6696 Thèse Bibliothèque principale Thèses Disponible
Titre : Exploration des potentialites therapeutiques de la phytopharmacopee traditionnelle algerienne : Etude de quelques plantes a activite cicatrisante. Type de document : texte imprimé Auteurs : Ahmed Boukeloua, Auteur ; Abdelmalik Belkhiri, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 158 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Biologie et écologie végétale:Biotechnologie Végétale Argania spinosa Opuntia ficus-indica Pistacia lentiscus préparation huileuse composition effet cicatrisant plaies d’excision lapins oily préparation wound heaking effet excised wound rabbits لمستحضرات الزيتية التركيب فعالية التئام الجروح الأرنب Index. décimale : 570 Sciences de la vie. Biologie Résumé : The wound healing potentialities of traditional Algerian phyto-pharmacopeia lie usually in some oily preparations, that their nutritional and pharmacological properties are related to an overall and synergic action of their bioactive constituents. This study resets on measuring of some physico-chemical and phytochemical parameters (chromatography HPlC, GC-MS and LC-MS/MS) of argane oil (HAS), of lipophylic extracts obtained from lentiscus fruits (EHPL) and Barbary fig seeds (EHOFI), and alcoholic extracts (EA) from the three plants, as well as a toxico-pharmacological evaluation of three oily preparations in animal (mousse, rabbit).
Obtained hysico-chemical parameters for the three oily preparations are comparable to those
published for similar preparation. The phytochemical tests showed the relative high contents
In these three plants of lipophylic extracting material; of proteins (EHOFI 28.39, HAS 26.21
and EHPL 23.85%), of unsaturated fatty acids (HAS 88, EHOFI 81.2 and EHPL 74.15%), of
unsaponifiable [α-tocophérol (EHOFI 21.34, EHPL 15.8 et HAS 7.44mg/100g) ; et phytostérols (EHPL 261, EHOFI 146, et HAS 134 mg/100g)], of total phenols for EAAS (35.57mg/g) and high total flavonoïds for the three alcoholic extract. The quantification of main constituents showed that EHOFI is riche on -linolénic ac. (57 %), while the fatty acids oleic and linoleic are presents in high quantities in HAS (44.4 et 36,69 %) and EHPL (48.91 et 21,86 %) respectively. -sitostérol is the main constituent for the three oily preparations. EAPL extract showed a dominant presence of gallic ac. (2092,39µg/g), quinic ac. (1519,84 µg/g), while EAOFI showed the presence of quinic ac. (83,57 µg/g) and chlorogénic ac. (16,37µg/g), as high polyphénols contents. On the toxicological part, the three oily products tested on rabbits, are considered non irritant neither on eye and skin, nor on anal mucosa. Their acute toxicity study on mice showed an absence or low down toxicity of the three oily preparations, by oral and intraperitonel routes. The evaluation of wound healing activity of the three oily preparations on excised wounds on rabbits showed less convincing results for EHPL than those obtained for EHOFI and HAS. These two latter treatments promote significantly (p≤0.05*) wound healing process on rabbits wounds during all treatment period.
Note de contenu :
Article 1:Acute toxicity of Opuntia ficus indica and Pistacia lentiscusseed
oils in mice.A. Boukelouaa,e, A. Belkhirib, Z. Djerroua, L. Bahric, N. Boulebdad, Y. Hamdi Pachaa.
Article 2:Chemical profiling and total thickness-excised wound-healing activity of Pistacia lentiscus L. fruits growing in Algeria.Ahmed Boukeloua1*, Abdelmalik Belkhiri2, Mustafa Abdullah Yilmaz3 and Hamdi Temel4Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BOU6978.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=11124 Exploration des potentialites therapeutiques de la phytopharmacopee traditionnelle algerienne : Etude de quelques plantes a activite cicatrisante. [texte imprimé] / Ahmed Boukeloua, Auteur ; Abdelmalik Belkhiri, Directeur de thèse . - جامعة الإخوة منتوري قسنطينة, 2016 . - 158 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Biologie et écologie végétale:Biotechnologie Végétale Argania spinosa Opuntia ficus-indica Pistacia lentiscus préparation huileuse composition effet cicatrisant plaies d’excision lapins oily préparation wound heaking effet excised wound rabbits لمستحضرات الزيتية التركيب فعالية التئام الجروح الأرنب Index. décimale : 570 Sciences de la vie. Biologie Résumé : The wound healing potentialities of traditional Algerian phyto-pharmacopeia lie usually in some oily preparations, that their nutritional and pharmacological properties are related to an overall and synergic action of their bioactive constituents. This study resets on measuring of some physico-chemical and phytochemical parameters (chromatography HPlC, GC-MS and LC-MS/MS) of argane oil (HAS), of lipophylic extracts obtained from lentiscus fruits (EHPL) and Barbary fig seeds (EHOFI), and alcoholic extracts (EA) from the three plants, as well as a toxico-pharmacological evaluation of three oily preparations in animal (mousse, rabbit).
Obtained hysico-chemical parameters for the three oily preparations are comparable to those
published for similar preparation. The phytochemical tests showed the relative high contents
In these three plants of lipophylic extracting material; of proteins (EHOFI 28.39, HAS 26.21
and EHPL 23.85%), of unsaturated fatty acids (HAS 88, EHOFI 81.2 and EHPL 74.15%), of
unsaponifiable [α-tocophérol (EHOFI 21.34, EHPL 15.8 et HAS 7.44mg/100g) ; et phytostérols (EHPL 261, EHOFI 146, et HAS 134 mg/100g)], of total phenols for EAAS (35.57mg/g) and high total flavonoïds for the three alcoholic extract. The quantification of main constituents showed that EHOFI is riche on -linolénic ac. (57 %), while the fatty acids oleic and linoleic are presents in high quantities in HAS (44.4 et 36,69 %) and EHPL (48.91 et 21,86 %) respectively. -sitostérol is the main constituent for the three oily preparations. EAPL extract showed a dominant presence of gallic ac. (2092,39µg/g), quinic ac. (1519,84 µg/g), while EAOFI showed the presence of quinic ac. (83,57 µg/g) and chlorogénic ac. (16,37µg/g), as high polyphénols contents. On the toxicological part, the three oily products tested on rabbits, are considered non irritant neither on eye and skin, nor on anal mucosa. Their acute toxicity study on mice showed an absence or low down toxicity of the three oily preparations, by oral and intraperitonel routes. The evaluation of wound healing activity of the three oily preparations on excised wounds on rabbits showed less convincing results for EHPL than those obtained for EHOFI and HAS. These two latter treatments promote significantly (p≤0.05*) wound healing process on rabbits wounds during all treatment period.
Note de contenu :
Article 1:Acute toxicity of Opuntia ficus indica and Pistacia lentiscusseed
oils in mice.A. Boukelouaa,e, A. Belkhirib, Z. Djerroua, L. Bahric, N. Boulebdad, Y. Hamdi Pachaa.
Article 2:Chemical profiling and total thickness-excised wound-healing activity of Pistacia lentiscus L. fruits growing in Algeria.Ahmed Boukeloua1*, Abdelmalik Belkhiri2, Mustafa Abdullah Yilmaz3 and Hamdi Temel4Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BOU6978.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=11124 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BOU/6978 BOU/6978 Thèse Bibliothèque principale Thèses Disponible
