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Partager le résultat de cette recherche Interroger des sources externesComportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. / Sara Himour ép Cherrier
Titre : Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. Type de document : texte imprimé Auteurs : Sara Himour ép Cherrier, Auteur ; Abdelouahab Yahia, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2018 Importance : 209 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Olea europaea L. morphologie physiologie HPLC Oleuropéine activité biologique antioxydante anticoagulante antibactérienne morphology physiology Oleuropein biological activity antioxidant anticoagulant antibacterial ???????????? L??????????? ?????????? HPLC?????????? ?????? ????????? ?????? ??????? ???? ?????? ????
?????????Index. décimale : 570 Sciences de la vie. Biologie Résumé : The present study focuses on the biological, physiological and biochemical behavior of the cultivated olive tree, Olea europaea L., represented by four varieties sampled at the Maazouzi Lakhdar station, Mila: Sigoise, Rougette, Chemlel and Dathier. The morphological characterizations (quantitative and qualitative), relating to the leaves, fruits and cores, described in the descriptors of the International Olive Council (IOC, 2003), revealed differences between the varieties. The set of morphological traits assessed during the three years of study (2013-2014- 2015) revealed a significant difference between the varieties studied confirmed by coefficients of
variation ranging from 2.81% to 39.14%. Positive correlations between mean precipitation, duration of insolations and morphological characters ranged from r = 0.839 to 0.946, and negative for fruit width and nuclei with temperature.
The results of the analysis of the biochemical characterization data revealed a great difference between the varieties. The most important lipid content was recorded in Sigoise leaf and fruit, Rougette gave the best sugar content in the leaves, as well as in Chemlel fruits. The qualitative analysis performed by phytochemical screening revealed the presence of several families of natural compounds in both organs. Rougette has been the dominant variety for total leaf and fruit phenol and flavonoid content, and Dathier for tannins. Quantitative analyzes of the phenolic compounds identified in the hydromethanol extracts by HPLC identified four
compounds: fumaric acid, gallic acid, oleuropein and caffeic acid, seven compounds in the leaves: fumaric acid, gallic acid, oleuropein, 4-hydroxybenzoic acid acid, caffeic acid, ellagic acid and t-3 hydroxyroamic acid, with a significant dominance of Oleuropein.
The evaluation of the biological potential of leaf and fruit extracts, revealed a significant anticoagulant activity in Chemlel for both organs and an antioxidant power of interest in Rougette leaves and Sigois fruits. All extracts have an important antibacterial power, extracts of leaf at Rougette gave a better zone of inhibition against S. aureus.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HIM7315.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10931 Comportements biologique, physiologique, biochimique et l’activité biologique de quatre variétés d’olivier (Olea europeae L.) dans l’Est Algérien. [texte imprimé] / Sara Himour ép Cherrier, Auteur ; Abdelouahab Yahia, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2018 . - 209 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Olea europaea L. morphologie physiologie HPLC Oleuropéine activité biologique antioxydante anticoagulante antibactérienne morphology physiology Oleuropein biological activity antioxidant anticoagulant antibacterial ???????????? L??????????? ?????????? HPLC?????????? ?????? ????????? ?????? ??????? ???? ?????? ????
?????????Index. décimale : 570 Sciences de la vie. Biologie Résumé : The present study focuses on the biological, physiological and biochemical behavior of the cultivated olive tree, Olea europaea L., represented by four varieties sampled at the Maazouzi Lakhdar station, Mila: Sigoise, Rougette, Chemlel and Dathier. The morphological characterizations (quantitative and qualitative), relating to the leaves, fruits and cores, described in the descriptors of the International Olive Council (IOC, 2003), revealed differences between the varieties. The set of morphological traits assessed during the three years of study (2013-2014- 2015) revealed a significant difference between the varieties studied confirmed by coefficients of
variation ranging from 2.81% to 39.14%. Positive correlations between mean precipitation, duration of insolations and morphological characters ranged from r = 0.839 to 0.946, and negative for fruit width and nuclei with temperature.
The results of the analysis of the biochemical characterization data revealed a great difference between the varieties. The most important lipid content was recorded in Sigoise leaf and fruit, Rougette gave the best sugar content in the leaves, as well as in Chemlel fruits. The qualitative analysis performed by phytochemical screening revealed the presence of several families of natural compounds in both organs. Rougette has been the dominant variety for total leaf and fruit phenol and flavonoid content, and Dathier for tannins. Quantitative analyzes of the phenolic compounds identified in the hydromethanol extracts by HPLC identified four
compounds: fumaric acid, gallic acid, oleuropein and caffeic acid, seven compounds in the leaves: fumaric acid, gallic acid, oleuropein, 4-hydroxybenzoic acid acid, caffeic acid, ellagic acid and t-3 hydroxyroamic acid, with a significant dominance of Oleuropein.
The evaluation of the biological potential of leaf and fruit extracts, revealed a significant anticoagulant activity in Chemlel for both organs and an antioxidant power of interest in Rougette leaves and Sigois fruits. All extracts have an important antibacterial power, extracts of leaf at Rougette gave a better zone of inhibition against S. aureus.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/HIM7315.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10931 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité HIM/7315 HIM/7315 Thèse Bibliothèque principale Thèses Disponible
Titre : Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques Type de document : texte imprimé Auteurs : Ilhem Labed ep Zouad, Auteur ; Zahia Kabouche, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2015 Importance : 211 f. Format : 30 cm. Note générale : 2 copies imprimes disponibles Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique Ferula vesceritensis Coss. & Dur. antioxydante anticholinestérase antibactérienne couplage oxydant énamides pipéridines hydroboration hydrogénation Pistacia atlantica Desf. antioxidant anticholinesterase antibacterial oxidative coupling enamides hydrogenation hydrobration piperidines Index. décimale : 540 Chimie et sciences connexes Résumé : In a first part we studied the chemical composition and biological activities of Pistacia
atlantica Desf. and Ferula vesceritensis Coss. & Dur. The GC and GC-MS analyses
showed that the essential oils of P. atlantica are rich in α-pinene, limonene and spatulenol,
while β-phellandrene, α-terpinene, β-elemene, γ-gurjunene and germacrene-B were found
as major components, for the first time for the essential oils of the genus Pistacia .
α-Pinene and β- pinene were predominant in the essential oils of Ferula vesceritensis;
however the first time that α-phellandrene, fenchylacetate, elixene, l'aristolene and cartol
were found as main components in the essential oils of the genus Ferula . The both essential
oils of P. atlantica . and F. vesceritensis exhibited a good antibacterial activity against
clinical isolated bacteria and food borne pathogens. The essential oils of P. atlantica
possess an important antioxidant effect which were determined using β-carotene-linoleic
acid, DPPH- and ABTS•+ -scavenging activities, metal chelating effect and CUPRAC
assays. The essential oils showed a moderate anticholinestérase activity compared with
galantamin for the inhibitory activity of principal enzymes of Alzheimer’s disease AChE
and BChE.
In a second part, we synthesized 12 new piperidine derivatives, which have been achieved
through [Cp*Ru]-catalyzed intermolecular coupling of allylic alcohols and propargylic
amides with water as the only side product, and demonstrated that the selective
oxidativecoupling cinnamyl alcohol derivatives and 2-substituted allylic alcohols. This
methodology allows the access to 3,4- and 3,5-disubstituted enamides as valuable
scaffolds for the preparation of 3-methylpiperidine derivatives through selective [Cp*Ru]
catalyzed alkene hydrogenation.Diplôme : Doctorat En ligne : ../theses/chimie/LAB6834.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10126 Composition chimique et évaluation des activites biologiques des huiles essentielles de Pistacia atlantica Desf.et de Ferula vesceritensis Coss. & Dur. et synthese catalytique de nouveaux dérivés pipéridiniques [texte imprimé] / Ilhem Labed ep Zouad, Auteur ; Zahia Kabouche, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2015 . - 211 f. ; 30 cm.
2 copies imprimes disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Chimie pharmaceutique Ferula vesceritensis Coss. & Dur. antioxydante anticholinestérase antibactérienne couplage oxydant énamides pipéridines hydroboration hydrogénation Pistacia atlantica Desf. antioxidant anticholinesterase antibacterial oxidative coupling enamides hydrogenation hydrobration piperidines Index. décimale : 540 Chimie et sciences connexes Résumé : In a first part we studied the chemical composition and biological activities of Pistacia
atlantica Desf. and Ferula vesceritensis Coss. & Dur. The GC and GC-MS analyses
showed that the essential oils of P. atlantica are rich in α-pinene, limonene and spatulenol,
while β-phellandrene, α-terpinene, β-elemene, γ-gurjunene and germacrene-B were found
as major components, for the first time for the essential oils of the genus Pistacia .
α-Pinene and β- pinene were predominant in the essential oils of Ferula vesceritensis;
however the first time that α-phellandrene, fenchylacetate, elixene, l'aristolene and cartol
were found as main components in the essential oils of the genus Ferula . The both essential
oils of P. atlantica . and F. vesceritensis exhibited a good antibacterial activity against
clinical isolated bacteria and food borne pathogens. The essential oils of P. atlantica
possess an important antioxidant effect which were determined using β-carotene-linoleic
acid, DPPH- and ABTS•+ -scavenging activities, metal chelating effect and CUPRAC
assays. The essential oils showed a moderate anticholinestérase activity compared with
galantamin for the inhibitory activity of principal enzymes of Alzheimer’s disease AChE
and BChE.
In a second part, we synthesized 12 new piperidine derivatives, which have been achieved
through [Cp*Ru]-catalyzed intermolecular coupling of allylic alcohols and propargylic
amides with water as the only side product, and demonstrated that the selective
oxidativecoupling cinnamyl alcohol derivatives and 2-substituted allylic alcohols. This
methodology allows the access to 3,4- and 3,5-disubstituted enamides as valuable
scaffolds for the preparation of 3-methylpiperidine derivatives through selective [Cp*Ru]
catalyzed alkene hydrogenation.Diplôme : Doctorat En ligne : ../theses/chimie/LAB6834.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10126 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité LAB/6834 LAB/6834 Thèse Bibliothèque principale Thèses Disponible
Titre : Effet des extraits de la plante médicinale Ruta montana) (الفيجلsur la cardiotoxicité induite par la doxorubicine et sur la multi-drug résistances (MDR) des cellules cancéreuses ovarien (A2780) Type de document : texte imprimé Auteurs : Wahiba Kara Ali, Auteur ; N. Abidli, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2017 Importance : 160 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : Ruta montana Doxorubicine Cardiotoxicité Multi-drug résistance Stress oxydant Antioxydant Flavonoides Cardiotoxicity Multidrug resistance Oxidative
stress Antioxidant Flavonoids ????????????? ?????? ??????? ???????? ???????? ??????? ??????? ???????? ?????? ?????? ???????Index. décimale : 570 Sciences de la vie. Biologie Résumé : This study was conducted to search for the preventive effect of medicinal plant Ruta montana
extract on oxidative stress induced by doxorubicine (DOX) and its properties to reverse
doxorubicin resistance in ovarian cancer cell line (A2780). Organic extracts were obtained by
maceration with three solvents: petroleum ether, ethyl acetate and butanol. The yields were:
15,04%, 3,55% and 25,14%.respectively. A phytochemical screening in methanol extract
revealed that the plant contain the flavonoids, saponins, tannins, coumarins, reducing component
and the alkaloids. The quantitative study showed that the butanolic extract (BERM) has
significant amount of flavonoids (80.85±0.78mg EQ / g dry extract), followed by ethyl acetate
extract (AEERM) (15.27 ±0.62 EQ / g dry extract) and petroleum ether extract has the lowest
flavonoids content (PEERM) (9.71±1.13 mgEQ/g dry extract). When the total phenolic contents
was: 687.5, 595.83 and 146.33 mg EGA / g dry extract, in the BERM, AEERM and PEERM
respectively. The qualitative analysis of the three methanolic crude extract via thin layer
chromatography (TLC) has shown the presence of the anthocyanidin 3-glycosids, flavons et
flavonols glycosids (hétérosids), flavonols avec 3-OH libre, flavonons ou aurons, isoflavons, the
phénolic acids, Flavonols et 4-OH chalcons. The évaluation of antioxidant activity by the
reduction of free radical DPPH method showed that The highest DPPH radical scavenging
activity was observed with AEERM (IC50 = 0.126 ± 0.002 mg/ ml), followed by BERM (0.135
± 0.0006 mg/ ml) and PEERM (IC50 =0.185± 0.002 mg/ ml). The study of preventive effect of
AEERM on oxidative stress induced by DOX in wistar rats clearly show that DOX (15 mg/kg
i.p) induced animal cardiotoxicity characterized by an increase of cardiac enzyme activity
(CKMB, LDH, l’ALAT et l’ASAT) in serum, the increase in the concentration of
malondialdéhyde (MDA), antioxydant enzyme activity, catalase (CAT) and Glutathion- Stransférase (GST) and a decrease of cardiac cytosolic reduced glutathione (GSH) with a different
pathological changes in the heart. However pretreated animals with EAERM (100 mg/kg orally
during 15 days), showed a decrease of cardiac enzymes activities 24 %, 35, 69%, 21,25 % et
8,10 % respectively to CKMB, LDH, l’ALAT and l’ASAT. The preatretment with the extract
improved antioxidant status in the heart by a decrease in the cardiac MDA concentration by 29,7
% and activity of antioxydants enzymes by 17,91% et 29,78% respectively to CAT et la GST.
In addition, the pretreated rats by the extract showed an increase of GSH level (83,76 %)
compared with DOX-treated animals. Histological study shows that the extract resulted in a
reduction of severe cardiac damages observed in DOX-treated animals. The reversal of
multidrug resistance for DOX in human ovarian adenocarcinoma, cell lines (A2780 DX3) using
MTT assay showed that AEERM was very effective at reversing the resistant in dose dependent
manner with the Reversion Factor (RF =8.62, 05.77 and 02.30 respectively for the
concentrations 40, 10 and 2.5 mg/ml) followed by BERM (FR=05.07 and 02.43 for the
concentrations 40 and 10 mg/ml respectively), then the PEERM had the lowest reversal
resistance effect (RF betwen 1.01 to 1.08). The present study suggests that AEERM can
ameliorate the oxidative stress involved in the pathogenesis of doxorubicine- induced
cardiotoxicity and can reverse the multidrug resistance for DOX.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/KAR7158.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10435 Effet des extraits de la plante médicinale Ruta montana) (الفيجلsur la cardiotoxicité induite par la doxorubicine et sur la multi-drug résistances (MDR) des cellules cancéreuses ovarien (A2780) [texte imprimé] / Wahiba Kara Ali, Auteur ; N. Abidli, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2017 . - 160 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : Ruta montana Doxorubicine Cardiotoxicité Multi-drug résistance Stress oxydant Antioxydant Flavonoides Cardiotoxicity Multidrug resistance Oxidative
stress Antioxidant Flavonoids ????????????? ?????? ??????? ???????? ???????? ??????? ??????? ???????? ?????? ?????? ???????Index. décimale : 570 Sciences de la vie. Biologie Résumé : This study was conducted to search for the preventive effect of medicinal plant Ruta montana
extract on oxidative stress induced by doxorubicine (DOX) and its properties to reverse
doxorubicin resistance in ovarian cancer cell line (A2780). Organic extracts were obtained by
maceration with three solvents: petroleum ether, ethyl acetate and butanol. The yields were:
15,04%, 3,55% and 25,14%.respectively. A phytochemical screening in methanol extract
revealed that the plant contain the flavonoids, saponins, tannins, coumarins, reducing component
and the alkaloids. The quantitative study showed that the butanolic extract (BERM) has
significant amount of flavonoids (80.85±0.78mg EQ / g dry extract), followed by ethyl acetate
extract (AEERM) (15.27 ±0.62 EQ / g dry extract) and petroleum ether extract has the lowest
flavonoids content (PEERM) (9.71±1.13 mgEQ/g dry extract). When the total phenolic contents
was: 687.5, 595.83 and 146.33 mg EGA / g dry extract, in the BERM, AEERM and PEERM
respectively. The qualitative analysis of the three methanolic crude extract via thin layer
chromatography (TLC) has shown the presence of the anthocyanidin 3-glycosids, flavons et
flavonols glycosids (hétérosids), flavonols avec 3-OH libre, flavonons ou aurons, isoflavons, the
phénolic acids, Flavonols et 4-OH chalcons. The évaluation of antioxidant activity by the
reduction of free radical DPPH method showed that The highest DPPH radical scavenging
activity was observed with AEERM (IC50 = 0.126 ± 0.002 mg/ ml), followed by BERM (0.135
± 0.0006 mg/ ml) and PEERM (IC50 =0.185± 0.002 mg/ ml). The study of preventive effect of
AEERM on oxidative stress induced by DOX in wistar rats clearly show that DOX (15 mg/kg
i.p) induced animal cardiotoxicity characterized by an increase of cardiac enzyme activity
(CKMB, LDH, l’ALAT et l’ASAT) in serum, the increase in the concentration of
malondialdéhyde (MDA), antioxydant enzyme activity, catalase (CAT) and Glutathion- Stransférase (GST) and a decrease of cardiac cytosolic reduced glutathione (GSH) with a different
pathological changes in the heart. However pretreated animals with EAERM (100 mg/kg orally
during 15 days), showed a decrease of cardiac enzymes activities 24 %, 35, 69%, 21,25 % et
8,10 % respectively to CKMB, LDH, l’ALAT and l’ASAT. The preatretment with the extract
improved antioxidant status in the heart by a decrease in the cardiac MDA concentration by 29,7
% and activity of antioxydants enzymes by 17,91% et 29,78% respectively to CAT et la GST.
In addition, the pretreated rats by the extract showed an increase of GSH level (83,76 %)
compared with DOX-treated animals. Histological study shows that the extract resulted in a
reduction of severe cardiac damages observed in DOX-treated animals. The reversal of
multidrug resistance for DOX in human ovarian adenocarcinoma, cell lines (A2780 DX3) using
MTT assay showed that AEERM was very effective at reversing the resistant in dose dependent
manner with the Reversion Factor (RF =8.62, 05.77 and 02.30 respectively for the
concentrations 40, 10 and 2.5 mg/ml) followed by BERM (FR=05.07 and 02.43 for the
concentrations 40 and 10 mg/ml respectively), then the PEERM had the lowest reversal
resistance effect (RF betwen 1.01 to 1.08). The present study suggests that AEERM can
ameliorate the oxidative stress involved in the pathogenesis of doxorubicine- induced
cardiotoxicity and can reverse the multidrug resistance for DOX.
Diplôme : Doctorat en sciences En ligne : ../theses/biologie/KAR7158.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10435 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire
Titre : Etude écophysiologique, développement et importance des plantes médicinales du genre Mentha dans le Parc National d’El-Kala (Nord-Est Algérie). Type de document : texte imprimé Auteurs : Amina Benabdallah, Auteur ; Chaabane Rahmoune, Directeur de thèse Importance : 152 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
BiologieTags : M. aquatica M. arvensis Mx piperita M.pulegium M. rotundifolia M. x villosa NPEK ElKala RAMSAR phenols flavonoids tannins essential oil antioxidant acetylcholinesterase PNEK phénols, flavonoïdes, huile essentielle antioxydant acétylcholinestérase Index. décimale : 570 Sciences de la vie. Biologie Résumé : Mentha species are widely used by native habitants of El-Tarf region, as condiment, flavor or
herb in culinary preparations but also used for therapeutic properties as carminative, sedative,
antispasmodic and well known to treat stomach pain.
The aim of this work was first to inventory and geolocalisate Mentha species of the National
Park of El-Kala and then to investigate the total phenolics, flavonoids and tannins content and
the in-vitro antioxidant activities of methanolic extracts and essential oils, then to evaluate the
chemical composition of essential oils obtained from aerial parts of six wildMentha species:
M. aquatica, M. arvensis, M x piperita, M. pulegium, M. rotundifolia and M x villosa.
Chemical composition was analyzed by GC-MS method and biological activities investigated
by DPPH, B-carotene bleaching and ion chelating assays for the antioxidant activity, as well
as the inhibition of acetycholinesterase. The methanol extracts of mints were rich in phenolic
compounds and exhibited a powerful antioxidant activity ranged from7.5µg/mlto44.66
µg/ml,which varied significantly among species. M. aquatica stands out with an efficient
antioxidant ability which is correlated to the high total phenolics contents, followed by M.
arvensis and M. piperita with very close values, comparing to M. pulegium, M. rotundifolia
and M. villosa with lowest values. Qualitative and quantitative variations were observed
among species. The highest yield of oils, obtained by hydrodistillation, was recorded for M.
pulegium with 1.8%. A total of 27 compounds were identified with the predominance of
oxygenated monoterpenes such as menthofurane (73.38%), rotundifolone (65.99%), pulegone
(59.12%), menthol (49.89%), menthone (20.84%), neomenthol (20.76%), 1.8-cineol (18.16%)
and β-caryophyllene (12.55%). In general, M. aquatica exhibited the strongest antioxidant
level with IC50 of 0.69±0.06 mg/ml assessed by DPPH assay, 0.16±0.02 mg/ml by β-Carotene
bleaching and 1.73±0.17 mg/ml by ferrous ion chelating method. Whereas M. arvensisstood
out with IC50 of 27.5mg/ml for acetylcholinesterase inhibitory.These results show that Mentha
species from NPEK have a great potential of polyphenols which can be used as a natural food
preservative and antioxidant source. Moreover, mints could be exploited for their
pharmacological application in order to prevent induced diseases relied to oxidative stress.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BEN7087.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10514 Etude écophysiologique, développement et importance des plantes médicinales du genre Mentha dans le Parc National d’El-Kala (Nord-Est Algérie). [texte imprimé] / Amina Benabdallah, Auteur ; Chaabane Rahmoune, Directeur de thèse . - [s.d.] . - 152 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
BiologieTags : M. aquatica M. arvensis Mx piperita M.pulegium M. rotundifolia M. x villosa NPEK ElKala RAMSAR phenols flavonoids tannins essential oil antioxidant acetylcholinesterase PNEK phénols, flavonoïdes, huile essentielle antioxydant acétylcholinestérase Index. décimale : 570 Sciences de la vie. Biologie Résumé : Mentha species are widely used by native habitants of El-Tarf region, as condiment, flavor or
herb in culinary preparations but also used for therapeutic properties as carminative, sedative,
antispasmodic and well known to treat stomach pain.
The aim of this work was first to inventory and geolocalisate Mentha species of the National
Park of El-Kala and then to investigate the total phenolics, flavonoids and tannins content and
the in-vitro antioxidant activities of methanolic extracts and essential oils, then to evaluate the
chemical composition of essential oils obtained from aerial parts of six wildMentha species:
M. aquatica, M. arvensis, M x piperita, M. pulegium, M. rotundifolia and M x villosa.
Chemical composition was analyzed by GC-MS method and biological activities investigated
by DPPH, B-carotene bleaching and ion chelating assays for the antioxidant activity, as well
as the inhibition of acetycholinesterase. The methanol extracts of mints were rich in phenolic
compounds and exhibited a powerful antioxidant activity ranged from7.5µg/mlto44.66
µg/ml,which varied significantly among species. M. aquatica stands out with an efficient
antioxidant ability which is correlated to the high total phenolics contents, followed by M.
arvensis and M. piperita with very close values, comparing to M. pulegium, M. rotundifolia
and M. villosa with lowest values. Qualitative and quantitative variations were observed
among species. The highest yield of oils, obtained by hydrodistillation, was recorded for M.
pulegium with 1.8%. A total of 27 compounds were identified with the predominance of
oxygenated monoterpenes such as menthofurane (73.38%), rotundifolone (65.99%), pulegone
(59.12%), menthol (49.89%), menthone (20.84%), neomenthol (20.76%), 1.8-cineol (18.16%)
and β-caryophyllene (12.55%). In general, M. aquatica exhibited the strongest antioxidant
level with IC50 of 0.69±0.06 mg/ml assessed by DPPH assay, 0.16±0.02 mg/ml by β-Carotene
bleaching and 1.73±0.17 mg/ml by ferrous ion chelating method. Whereas M. arvensisstood
out with IC50 of 27.5mg/ml for acetylcholinesterase inhibitory.These results show that Mentha
species from NPEK have a great potential of polyphenols which can be used as a natural food
preservative and antioxidant source. Moreover, mints could be exploited for their
pharmacological application in order to prevent induced diseases relied to oxidative stress.Diplôme : Doctorat en sciences En ligne : ../theses/biologie/BEN7087.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10514 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité BEN/7087 BEN/7087 Thèse Bibliothèque principale Thèses Disponible
Titre : Etude phytochimique et biologique de Bituminaria bituminosa(L.)C.H.Stirton (Fabaceae) et Centaaurea dimorphaViv. (Asteraceae) Type de document : texte imprimé Auteurs : Salima Azzouzi ep Ouchtati, Auteur ; Kamel Medjroubi, Directeur de thèse Editeur : جامعة الإخوة منتوري قسنطينة Année de publication : 2016 Importance : 135 f. Format : 30 cm. Note générale : 2 copies imprimées disponibles
Langues : Français (fre) Catégories : Français - Anglais
ChimieTags : Fabaceae Asteracea Bituminaria bituminosa Centaurea dimorpha antioxydante activité antibactérienne antioxidant antibacterial activity ??????? ????????? ??????? ??????? ????? ??????? ?????? ????? ????????? Index. décimale : 540 Chimie et sciences connexes Résumé : Our research includes the stady of the phytochemical and biological aspects of the two presented species Bituminaria bituminosa(L.) C.H.Stirton. which belongs to Fabaceae family and Centaurea dimorpha Viv. which belongs to Asteraceae family.
Several chromatographic methods were used in our work. Thes methods allowed us to isolate four products from B.bituminosa plant (only three have been identified), and five products from C.dimorpha plant (only four have been identified).
The identification of structures has been realised by combining the different spectrometric and spectroscopic methods (SMES, UV, RMN-1D,2D).
Butanolic extract of B.bituminosa species showed a weak antioxidant capacity. The various extracts of the two studied plants have shown a good antibacterial activity.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/AZZ6871.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10185 Etude phytochimique et biologique de Bituminaria bituminosa(L.)C.H.Stirton (Fabaceae) et Centaaurea dimorphaViv. (Asteraceae) [texte imprimé] / Salima Azzouzi ep Ouchtati, Auteur ; Kamel Medjroubi, Directeur de thèse . - [S.l.] : جامعة الإخوة منتوري قسنطينة, 2016 . - 135 f. ; 30 cm.
2 copies imprimées disponibles
Langues : Français (fre)
Catégories : Français - Anglais
ChimieTags : Fabaceae Asteracea Bituminaria bituminosa Centaurea dimorpha antioxydante activité antibactérienne antioxidant antibacterial activity ??????? ????????? ??????? ??????? ????? ??????? ?????? ????? ????????? Index. décimale : 540 Chimie et sciences connexes Résumé : Our research includes the stady of the phytochemical and biological aspects of the two presented species Bituminaria bituminosa(L.) C.H.Stirton. which belongs to Fabaceae family and Centaurea dimorpha Viv. which belongs to Asteraceae family.
Several chromatographic methods were used in our work. Thes methods allowed us to isolate four products from B.bituminosa plant (only three have been identified), and five products from C.dimorpha plant (only four have been identified).
The identification of structures has been realised by combining the different spectrometric and spectroscopic methods (SMES, UV, RMN-1D,2D).
Butanolic extract of B.bituminosa species showed a weak antioxidant capacity. The various extracts of the two studied plants have shown a good antibacterial activity.Diplôme : Doctorat en sciences En ligne : ../theses/chimie/AZZ6871.pdf Format de la ressource électronique : Permalink : https://bu.umc.edu.dz/md/index.php?lvl=notice_display&id=10185 Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité AZZ/6871 AZZ/6871 Thèse Bibliothèque principale Thèses Disponible
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